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We propose a mesh-based technique to aid in the classification of Alzheimer's disease dementia (ADD) using mesh representations of the cortex and subcortical structures. Deep learning methods for classification tasks that utilize structural…

图像与视频处理 · 电气工程与系统科学 2022-03-14 Emanuel A. Azcona , Pierre Besson , Yunan Wu , Arjun Punjabi , Adam Martersteck , Amil Dravid , Todd B. Parrish , S. Kathleen Bandt , Aggelos K. Katsaggelos

Early diagnosis of Alzheimer's disease (AD) is essential in preventing the disease's progression. Therefore, detecting AD from neuroimaging data such as structural magnetic resonance imaging (sMRI) has been a topic of intense investigation…

计算机视觉与模式识别 · 计算机科学 2023-02-01 Maha M. Alwuthaynani , Zahraa S. Abdallah , Raul Santos-Rodriguez

Background: Dementia, marked by cognitive decline, is a global health challenge. Alzheimer's disease (AD), the leading type, accounts for ~70% of cases. Electroencephalography (EEG) measures show promise in identifying AD risk, but…

信号处理 · 电气工程与系统科学 2024-11-28 Veronica Henao Isaza , David Aguillon , Carlos Andres Tobon Quintero , Francisco Lopera , John Fredy Ochoa Gomez

This Signal Processing Grand Challenge (SPGC) targets a difficult automatic prediction problem of societal and medical relevance, namely, the detection of Alzheimer's Dementia (AD). Participants were invited to employ signal processing and…

音频与语音处理 · 电气工程与系统科学 2023-01-16 Saturnino Luz , Fasih Haider , Davida Fromm , Ioulietta Lazarou , Ioannis Kompatsiaris , Brian MacWhinney

Progressive cognitive decline spanning across decades is characteristic of Alzheimer's disease (AD). Various predictive models have been designed to realize its early onset and study the long-term trajectories of cognitive test scores…

Alzheimer's disease (AD) is a common form of dementia that severely impacts patient health. As AD impairs the patient's language understanding and expression ability, the speech of AD patients can serve as an indicator of this disease. This…

音频与语音处理 · 电气工程与系统科学 2023-07-07 Hongmin Cai , Xiaoke Huang , Zhengliang Liu , Wenxiong Liao , Haixing Dai , Zihao Wu , Dajiang Zhu , Hui Ren , Quanzheng Li , Tianming Liu , Xiang Li

Understanding the distinction between causation and correlation is critical in Alzheimer's disease (AD) research, as it impacts diagnosis, treatment, and the identification of true disease drivers. This experiment investigates the…

人工智能 · 计算机科学 2025-06-13 Hamzah Dabool , Raghad Mustafa

Alzheimer's disease (AD) is one of the most common neurodegenerative diseases, with around 50 million patients worldwide. Accessible and non-invasive methods of diagnosing and characterising AD are therefore urgently required.…

神经元与认知 · 定量生物学 2021-07-14 Dominik Klepl , Fei He , Min Wu , Matteo De Marco , Daniel J. Blackburn , Ptolemaios Sarrigiannis

Early diagnosis, playing an important role in preventing progress and treating the Alzheimer\{'}s disease (AD), is based on classification of features extracted from brain images. The features have to accurately capture main AD-related…

机器学习 · 计算机科学 2016-11-15 Ehsan Hosseini-Asl , Robert Keynto , Ayman El-Baz

Early diagnosis, playing an important role in preventing progress and treating the Alzheimer's disease (AD), is based on classification of features extracted from brain images. The features have to accurately capture main AD-related…

机器学习 · 计算机科学 2016-07-05 Ehsan Hosseini-Asl , Georgy Gimel'farb , Ayman El-Baz

Alzheimer's disease is a common cognitive disorder in the elderly. Early and accurate diagnosis of Alzheimer's disease (AD) has a major impact on the progress of research on dementia. At present, researchers have used machine learning…

声音 · 计算机科学 2024-02-20 Xiaohui Zhang , Wenjie Fu , Mangui Liang

MEG are non invasive neuroimaging techniques with excellent temporal and spatial resolution, crucial for studying brain function in dementia and Alzheimer Disease. They identify changes in brain activity at various Alzheimer stages,…

Neuroimaging biomarkers that distinguish between typical brain aging and Alzheimer's disease (AD) are valuable for determining how much each contributes to cognitive decline. Machine learning models can derive multi-variate brain change…

Alzheimer's disease (AD) is the most prevalent form of dementia, and its early diagnosis is essential for slowing disease progression. Recent studies on multimodal neuroimaging fusion using MRI and PET have achieved promising results by…

计算机视觉与模式识别 · 计算机科学 2025-11-05 Delin Ma , Menghui Zhou , Jun Qi , Yun Yang , Po Yang

Alzheimer's Disease (AD) is an irreversible neurodegenerative disorder affecting millions of individuals today. The prognosis of the disease solely depends on treating symptoms as they arise and proper caregiving, as there are no current…

图像与视频处理 · 电气工程与系统科学 2024-12-17 Prayas Sanyal , Srinjay Mukherjee , Arkapravo Das , Anindya Sen

Deep Learning and DRUG-seq (Digital RNA with perturbation of genes) have attracted attention in drug discovery. However, the public DRUG-seq dataset is too small to be used for directly training a deep learning neural network from scratch.…

定量方法 · 定量生物学 2022-10-28 Yetao Wu , Han Liu , Jie Yan , Xiaolin Hu

The average life expectancy is increasing globally due to advancements in medical technology, preventive health care, and a growing emphasis on gerontological health. Therefore, developing technologies that detect and track aging-associated…

计算工程、金融与科学 · 计算机科学 2022-09-14 Saurav K. Aryal , Howard Prioleau , Legand Burge

We employ the Hopfield model as a simplified framework to explore both the memory deficits and the biochemical processes characteristic of Alzheimer's disease. By simulating neuronal death and synaptic degradation through increasing the…

神经元与认知 · 定量生物学 2024-10-11 Sai Nag Anurag Nangunoori , Akshara Karthic Mahadevan

Alzheimer disease (AD) is considered one of the leading causes of death in the United States, and there is no effective cure for it. Understanding the neuropathological mechanisms underlying AD is essential for identifying early, reliable…

This paper is a submission to the Alzheimer's Dementia Recognition through Spontaneous Speech (ADReSS) challenge, which aims to develop methods that can assist in the automated prediction of severity of Alzheimer's Disease from speech data.…

机器学习 · 计算机科学 2021-06-18 Morteza Rohanian , Julian Hough , Matthew Purver
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