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In this paper, we propose a novel variational generator framework for conditional GANs to catch semantic details for improving the generation quality and diversity. Traditional generators in conditional GANs simply concatenate the…

计算机视觉与模式识别 · 计算机科学 2019-09-24 Mingqi Hu , Deyu Zhou , Yulan He

Single-cell RNA sequencing (scRNA-seq) provides high-dimensional profiles of cellular states, enabling data-driven modeling of cellular dynamics over time. In practice, time-resolved scRNA-seq is collected at only a few discrete time points…

机器学习 · 计算机科学 2026-05-22 Siyu Pu , Qingqing Long , Xiaohan Huang , Haotian Chen , Jiajia Wang , Meng Xiao , Xiao Luo , Hengshu Zhu , Yuanchun Zhou , Xuezhi Wang

Background: Classifications in meta-research enable researchers to cope with an increasing body of scientific knowledge. They provide a framework for, e.g., distinguishing methods, reports, reproducibility, and evaluation in a knowledge…

软件工程 · 计算机科学 2022-09-22 Angelika Kaplan , Thomas Kühn , Ralf Reussner

Domain generalization for semantic segmentation aims to mitigate the degradation in model performance caused by domain shifts. However, in many real-world scenarios, we are unable to access the model parameters and architectural details due…

计算机视觉与模式识别 · 计算机科学 2026-03-31 Qingmei Li , Yang Zhang , Peifeng Zhang , Haohuan Fu , Juepeng Zheng

Consider learning a generative model for time-series data. The sequential setting poses a unique challenge: Not only should the generator capture the conditional dynamics of (stepwise) transitions, but its open-loop rollouts should also…

机器学习 · 统计学 2023-11-03 Daniel Jarrett , Ioana Bica , Mihaela van der Schaar

Probabilistic forecasting of multivariate time series is challenging due to non-stationarity, inter-variable dependencies, and distribution shifts. While recent diffusion and flow matching models have shown promise, they often ignore…

Large language models (LLMs) have achieved remarkable progress, yet their internal mechanisms remain largely opaque, posing a significant challenge to their safe and reliable deployment. Sparse autoencoders (SAEs) have emerged as a…

计算与语言 · 计算机科学 2026-02-11 Jiaojiao Han , Wujiang Xu , Mingyu Jin , Mengnan Du

In recent years, there has been an explosion of machine learning techniques for turbulence closure modeling, though many rely on augmenting existing models. While this has proven successful in single-phase flows, it breaks down for…

流体动力学 · 物理学 2021-06-22 S. Beetham , J. Capecelatro

Conditional generative models have achieved considerable success in the past few years, but usually require a lot of labeled data. Recently, ClusterGAN combines GAN with an encoder to achieve remarkable clustering performance via…

机器学习 · 计算机科学 2021-04-06 Fei Ding , Feng Luo , Yin Yang

Research in scene graph generation (SGG) usually considers two-stage models, that is, detecting a set of entities, followed by combining them and labeling all possible relationships. While showing promising results, the pipeline structure…

计算机视觉与模式识别 · 计算机科学 2023-06-12 Alakh Desai , Tz-Ying Wu , Subarna Tripathi , Nuno Vasconcelos

Here we propose the Reweighted Autoencoded Variational Bayes for Enhanced Sampling (RAVE) method, a new iterative scheme that uses the deep learning framework of variational autoencoders to enhance sampling in molecular simulations. RAVE…

化学物理 · 物理学 2018-02-13 Joao Marcelo Lamim Ribeiro , Pablo Bravo Collado , Yihang Wang , Pratyush Tiwary

Self-supervised learning excels at learning representations from large amounts of data. At the same time, generative models offer the complementary property of learning information about the underlying data generation process. In this…

机器学习 · 计算机科学 2025-08-15 Emanuele Sansone , Robin Manhaeve

Survival analysis stands as a pivotal process in cancer treatment research, crucial for predicting patient survival rates accurately. Recent advancements in data collection techniques have paved the way for enhancing survival predictions by…

机器学习 · 计算机科学 2024-07-26 Linhao Qu , Dan Huang , Shaoting Zhang , Xiaosong Wang

Stable diffusion models represent the state-of-the-art in data synthesis across diverse domains and hold transformative potential for applications in science and engineering, e.g., by facilitating the discovery of novel solutions and…

机器学习 · 计算机科学 2025-10-23 Stefano Zampini , Jacob K. Christopher , Luca Oneto , Davide Anguita , Ferdinando Fioretto

Grid-scale battery degradation unfolds over multi-year timescales under coupled electrochemical, thermal, and operational feedbacks difficult to capture using laboratory data or proprietary field datasets. This scarcity limits the…

应用物理 · 物理学 2026-03-17 Paolo Esquivel , Mark A. Harris , Stephen J. Harris

One of the major shortcomings of variational autoencoders is the inability to produce generations from the individual modalities of data originating from mixture distributions. This is primarily due to the use of a simple isotropic Gaussian…

机器学习 · 计算机科学 2019-12-02 Frantzeska Lavda , Magda Gregorová , Alexandros Kalousis

Gene regulation is a dynamic process that connects genotype and phenotype. Given the difficulty of physically mapping mammalian gene circuitry, we require new computational methods to learn regulatory rules. Natural language is a valuable…

定量方法 · 定量生物学 2022-10-27 William Connell , Umair Khan , Michael J. Keiser

Cellular differentiation is governed by gene regulatory networks, the high-dimensional stochastic biochemical systems that determine the transcriptional landscape and mediate cellular responses to signals and perturbations. Although…

分子网络 · 定量生物学 2026-04-29 Suryanarayana Maddu , Victor Chardès , Michael J. Shelley

Gene-gene interactions play a crucial role in the manifestation of complex human diseases. Uncovering significant gene-gene interactions is a challenging task. Here, we present an innovative approach utilizing data-driven computational…

人工智能 · 计算机科学 2024-10-22 Yifan Wu , Yuntao Yang , Zirui Liu , Zhao Li , Khushbu Pahwa , Rongbin Li , Wenjin Zheng , Xia Hu , Zhaozhuo Xu

Deep generative models for audio synthesis have recently been significantly improved. However, the task of modeling raw-waveforms remains a difficult problem, especially for audio waveforms and music signals. Recently, the realtime audio…

声音 · 计算机科学 2022-11-17 Seokjin Lee , Minhan Kim , Seunghyeon Shin , Daeho Lee , Inseon Jang , Wootaek Lim