相关论文: In Search of Lost DNA Sequence Pretraining

Recent analyses suggest that encoders pretrained for language modeling capture certain morpho-syntactic structure. However, probing frameworks for word vectors still do not report results on standard setups such as constituent and…

Neural network pretraining is gaining attention due to its outstanding performance in natural language processing applications. However, pretraining usually leverages predefined task sequences to learn general linguistic clues. The lack of…

Deep Learning (DL) techniques for Natural Language Processing have been evolving remarkably fast. Recently, the DL advances in language modeling, machine translation and paragraph understanding are so prominent that the potential of DL in…

Protein representation learning plays a crucial role in understanding the structure and function of proteins, which are essential biomolecules involved in various biological processes. In recent years, deep learning has emerged as a…

Reliable training of generative adversarial networks (GANs) typically require massive datasets in order to model complicated distributions. However, in several applications, training samples obey invariances that are \textit{a priori}…

Many important problems involving molecular property prediction from 3D structures have limited data, posing a generalization challenge for neural networks. In this paper, we describe a pre-training technique based on denoising that…

DNA-based storage is an emerging storage technology that provides high information density and long duration. Due to the physical constraints in the reading and writing processes, error correction in DNA storage poses several interesting…

Purpose: The aim of this work is to develop a neural network training framework for continual training of small amounts of medical imaging data and create heuristics to assess training in the absence of a hold-out validation or test set.…

Motivation. Large language models (LLMs) have exhibited remarkable proficiency in diverse software engineering (SE) tasks. Handling such tasks typically involves acquiring foundational coding knowledge on large, general-purpose datasets…

DNA is subject to large deformations in a wide range of biological processes. Two key examples illustrate how such deformations influence the readout of the genetic information: the sequestering of eukaryotic genes by nucleosomes, and DNA…

In the face of rapidly accumulating genomic data, our understanding of the RNA regulatory code remains incomplete. Recent self-supervised methods in other domains have demonstrated the ability to learn rules underlying the data-generating…

Gene essentiality refers to the degree to which a gene is necessary for the survival and reproductive efficacy of a living organism. Although the essentiality of non-coding genes has been documented, there are still aspects of non-coding…

Contrastive learning has become a popular technique to pre-train image encoders, which could be used to build various downstream classification models in an efficient way. This process requires a large amount of data and computation…

This paper investigates the critical problem of representation similarity evolution during cross-domain transfer learning, with particular focus on understanding why pre-trained models maintain effectiveness when adapted to medical imaging…

The literature has proposed several methods to finetune pretrained GANs on new datasets, which typically results in higher performance compared to training from scratch, especially in the limited-data regime. However, despite the apparent…

Graph neural networks (GNNs) are shown to be successful in modeling applications with graph structures. However, training an accurate GNN model requires a large collection of labeled data and expressive features, which might be inaccessible…

Language model pretraining involves training on extensive corpora, where data quality plays a pivotal role. In this work, we aim to directly estimate the contribution of data during pretraining and select pretraining data in an efficient…

What is the best way to learn a universal face representation? Recent work on Deep Learning in the area of face analysis has focused on supervised learning for specific tasks of interest (e.g. face recognition, facial landmark localization…

The study of correlation structure in the primary sequences of DNA is reviewed. The issues reviewed include: symmetries among 16 base-base correlation functions, accurate estimation of correlation measures, the relationship between $1/f$…

Deep convolutional neural networks (CNNs) have achieved remarkable success in various fields. However, training an excellent CNN is practically a trial-and-error process that consumes a tremendous amount of time and computer resources. To…