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Multiple Instance Learning (MIL) represents the predominant framework in Whole Slide Image (WSI) classification, covering aspects such as sub-typing, diagnosis, and beyond. Current MIL models predominantly rely on instance-level features…

计算机视觉与模式识别 · 计算机科学 2024-07-26 Heng Fang , Sheng Huang , Wenhao Tang , Luwen Huangfu , Bo Liu

State space models (SSMs) with selection mechanisms and hardware-aware architectures, namely Mamba, have recently demonstrated significant promise in long-sequence modeling. Since the self-attention mechanism in transformers has quadratic…

计算机视觉与模式识别 · 计算机科学 2024-04-29 Hanwei Zhang , Ying Zhu , Dan Wang , Lijun Zhang , Tianxiang Chen , Zi Ye

Whole slide images (WSIs) are gigapixel-scale digital images of H\&E-stained tissue samples widely used in pathology. The substantial size and complexity of WSIs pose unique analytical challenges. Multiple Instance Learning (MIL) has…

计算机视觉与模式识别 · 计算机科学 2024-08-20 Jun Wang , Yu Mao , Nan Guan , Chun Jason Xue

Multi-modal medical image synthesis involves nonlinear transformation of tissue signals between source and target modalities, where tissues exhibit contextual interactions across diverse spatial distances. As such, the utility of a network…

图像与视频处理 · 电气工程与系统科学 2025-10-21 Omer F. Atli , Bilal Kabas , Fuat Arslan , Arda C. Demirtas , Mahmut Yurt , Onat Dalmaz , Tolga Çukur

Hyperspectral Imaging (HSI) has proven to be a powerful tool for capturing detailed spectral and spatial information across diverse applications. Despite the advancements in Deep Learning (DL) and Transformer architectures for HSI…

计算机视觉与模式识别 · 计算机科学 2024-12-02 Muhammad Ahmad , Muhammad Usama , Manuel Mazzara , Salvatore Distefano

Pathological diagnosis is highly reliant on image analysis, where Regions of Interest (ROIs) serve as the primary basis for diagnostic evidence, while whole-slide image (WSI)-level tasks primarily capture aggregated patterns. To extract…

计算机视觉与模式识别 · 计算机科学 2026-05-08 Enhui Chai , Sicheng Chen , Tianyi Zhang , Xingyu Li , Tianxiang Cui

Representation learning from Gigapixel Whole Slide Images (WSI) poses a significant challenge in computational pathology due to the complicated nature of tissue structures and the scarcity of labeled data. Multi-instance learning methods…

图像与视频处理 · 电气工程与系统科学 2024-05-28 Ali Nasiri-Sarvi , Vincent Quoc-Huy Trinh , Hassan Rivaz , Mahdi S. Hosseini

In recent years, deep learning has shown near-expert performance in segmenting complex medical tissues and tumors. However, existing models are often task-specific, with performance varying across modalities and anatomical regions.…

计算机视觉与模式识别 · 计算机科学 2025-10-30 T-Mai Bui , Fares Bougourzi , Fadi Dornaika , Vinh Truong Hoang

Medical Hyperspectral Imaging (MHSI) offers potential for computational pathology and precision medicine. However, existing CNN and Transformer struggle to balance segmentation accuracy and speed due to high spatial-spectral dimensionality.…

图像与视频处理 · 电气工程与系统科学 2025-02-25 Shijie Lin , Boxiang Yun , Wei Shen , Qingli Li , Anqiang Yang , Yan Wang

Nuclei segmentation and classification provide an essential basis for tumor immune microenvironment analysis. The previous nuclei segmentation and classification models require splitting large images into smaller patches for training,…

计算机视觉与模式识别 · 计算机科学 2025-03-17 Ye Zhang , Zijie Fang , Yifeng Wang , Lingbo Zhang , Xianchao Guan , Yongbing Zhang

The field of neuromorphic computing has gained significant attention in recent years, aiming to bridge the gap between the efficiency of biological neural networks and the performance of artificial intelligence systems. This paper…

神经与进化计算 · 计算机科学 2024-08-23 Jiahao Qin , Feng Liu

Whole-slide image (WSI) classification in computational pathology is commonly formulated as slide-level Multiple Instance Learning (MIL) with a single global bag representation. However, slide-level MIL is fundamentally underconstrained:…

We address the challenging problem of whole slide image (WSI) classification. WSIs have very high resolutions and usually lack localized annotations. WSI classification can be cast as a multiple instance learning (MIL) problem when only…

计算机视觉与模式识别 · 计算机科学 2021-04-05 Bin Li , Yin Li , Kevin W. Eliceiri

State-space models (SSMs), exemplified by S4, have introduced a novel context modeling method by integrating state-space techniques into deep learning. However, they struggle with global context modeling due to their data-independent…

计算机视觉与模式识别 · 计算机科学 2025-03-28 Hamid Suleman , Syed Talal Wasim , Muzammal Naseer , Juergen Gall

Widely used traditional pipelines for subcortical brain segmentation are often inefficient and slow, particularly when processing large datasets. Furthermore, deep learning models face challenges due to the high resolution of MRI images and…

图像与视频处理 · 电气工程与系统科学 2024-10-15 Aaron Cao , Zongyu Li , Jordan Jomsky , Andrew F. Laine , Jia Guo

Medical image segmentation plays an important role in various clinical applications; however, existing deep learning models face trade-offs between efficiency and accuracy. Convolutional Neural Networks (CNNs) capture local details well but…

图像与视频处理 · 电气工程与系统科学 2025-10-20 Saqib Qamar , Mohd Fazil , Parvez Ahmad , Shakir Khan , Abu Taha Zamani

Transformers have become foundational for visual tasks such as object detection, semantic segmentation, and video understanding, but their quadratic complexity in attention mechanisms presents scalability challenges. To address these…

计算机视觉与模式识别 · 计算机科学 2025-02-12 Fady Ibrahim , Guangjun Liu , Guanghui Wang

Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…

计算机视觉与模式识别 · 计算机科学 2022-09-28 Jingwei Zhang , Xin Zhang , Ke Ma , Rajarsi Gupta , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Recent advances in multimodal learning have significantly improved cancer survival risk prediction. However, the joint prognostic potential of protein markers and histopathology images remains underexplored, largely due to the high cost and…

计算机视觉与模式识别 · 计算机科学 2026-03-19 Jing Dai , Chen Wu , Ming Wu , Qibin Zhang , Zexi Wu , Jingdong Zhang , Hongming Xu

State Space Models (SSMs), especially recent Mamba architecture, have achieved remarkable success in sequence modeling tasks. However, extending SSMs to computer vision remains challenging due to the non-sequential structure of visual data…

计算机视觉与模式识别 · 计算机科学 2026-03-23 Puskal Khadka , KC Santosh