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Increasingly complex applications involve large datasets in combination with non-linear and high dimensional mathematical models. In this context, statistical inference is a challenging issue that calls for pragmatic approaches that take…

数据分析、统计与概率 · 物理学 2013-01-31 Andreas Raue , Clemens Kreutz , Fabian Joachim Theis , Jens Timmer

This paper presents an efficient Bayesian framework for solving nonlinear, high-dimensional model calibration problems. It is based on a Variational Bayesian formulation that aims at approximating the exact posterior by means of solving an…

应用统计 · 统计学 2015-11-02 Isabell M. Franck , P. S. Koutsourelakis

Bayesian statistics has gained popularity in psychological research due to its intuitive uncertainty quantification and convenient information-updating rules. In many applications, however, prior distributions are introduced merely as…

统计方法学 · 统计学 2026-03-10 Yang Liu , Jonathan P. Williams , Jan Hannig

Variational Bayesian Inference is a popular methodology for approximating posterior distributions over Bayesian neural network weights. Recent work developing this class of methods has explored ever richer parameterizations of the…

We develop a fast and accurate grouped penalized credible region approach for variable selection and prediction in Bayesian high-dimensional linear regression. Most existing Bayesian methods either are subject to high computational costs…

统计方法学 · 统计学 2026-01-26 Weichang Yu , Khue-Dung Dang

To adopt neural networks in safety critical domains, knowing whether we can trust their predictions is crucial. Bayesian neural networks (BNNs) provide uncertainty estimates by averaging predictions with respect to the posterior weight…

机器学习 · 计算机科学 2021-03-17 Jannik Schmitt , Stefan Roth

Bayesian neural network models (BNN) have re-surged in recent years due to the advancement of scalable computations and its utility in solving complex prediction problems in a wide variety of applications. Despite the popularity and…

机器学习 · 统计学 2020-11-20 Shrijita Bhattacharya , Zihuan Liu , Tapabrata Maiti

Genetic association tests involving copy-number variants (CNVs) are complicated by the fact that CNVs span multiple markers at which measurements are taken. The power of an association test at a single marker is typically low, and it is…

统计方法学 · 统计学 2016-07-20 Yinglei Li , Patrick Breheny

Observational healthcare data offer the potential to estimate causal effects of medical products on a large scale. However, the confidence intervals and p-values produced by observational studies only account for random error and fail to…

应用统计 · 统计学 2024-05-02 Jami J. Mulgrave , David Madigan , George Hripcsak

Oral cancer ranks among the most prevalent cancers globally, with a particularly high mortality rate in regions lacking adequate healthcare access. Early diagnosis is crucial for reducing mortality; however, challenges persist due to…

计算机视觉与模式识别 · 计算机科学 2025-10-03 Akshay Bhagwan Sonawane , Lena D. Swamikannan , Lakshman Tamil

Bayesian entity resolution merges together multiple, noisy databases and returns the minimal collection of unique individuals represented, together with their true, latent record values. Bayesian methods allow flexible generative models…

统计方法学 · 统计学 2014-10-20 Tamara Broderick , Rebecca C. Steorts

Bayesian inference in deep neural networks is challenging due to the high-dimensional, strongly multi-modal parameter posterior density landscape. Markov chain Monte Carlo approaches asymptotically recover the true posterior but are…

A new method is proposed for the correction of confidence intervals when the original interval does not have the correct nominal coverage probabilities in the frequentist sense. The proposed method is general and does not require any…

统计计算 · 统计学 2013-08-30 P. Menendez , Y. Fan , P. H. Garthwaite , S. A. Sisson

Copy number variations in cancer cells and volatility fluctuations in stock prices are commonly manifested as changepoints occurring at the same positions across related data sequences. We introduce a Bayesian modeling framework, BASIC,…

统计方法学 · 统计学 2017-04-17 Zhou Fan , Lester Mackey

Estimation of the allele frequency at genetic markers is a key ingredient in biological and biomedical research, such as studies of human genetic variation or of the genetic etiology of heritable traits. As genetic data becomes increasingly…

应用统计 · 统计学 2007-12-18 Marc Coram , Hua Tang

In this paper, we address the fundamental problem of line spectral estimation in a Bayesian framework. We target model order and parameter estimation via variational inference in a probabilistic model in which the frequencies are…

信息论 · 计算机科学 2017-04-05 Mihai-Alin Badiu , Thomas Lundgaard Hansen , Bernard Henri Fleury

\noindent Hyper-parameter selection is a central practical problem in modern machine learning, governing regularization strength, model capacity, and robustness choices. Cross-validation is often computationally prohibitive at scale, while…

机器学习 · 统计学 2025-12-24 Hedibert Lopes , Nick Polson , Vadim Sokolov

Few Bayesian methods for analyzing high-dimensional sparse survival data provide scalable variable selection, effect estimation and uncertainty quantification. Such methods often either sacrifice uncertainty quantification by computing…

统计方法学 · 统计学 2022-07-06 Michael Komodromos , Eric Aboagye , Marina Evangelou , Sarah Filippi , Kolyan Ray

Bayesian Neural Networks (BNNs) offer a principled and natural framework for proper uncertainty quantification in the context of deep learning. They address the typical challenges associated with conventional deep learning methods, such as…

统计计算 · 统计学 2024-11-13 Zahra Moslemi , Yang Meng , Shiwei Lan , Babak Shahbaba

Integrative analyses based on statistically relevant associations between genomics and a wealth of intermediary phenotypes (such as imaging) provide vital insights into their clinical relevance in terms of the disease mechanisms. Estimates…