相关论文: AbLWR:A Context-Aware Listwise Ranking Framework f…

Accurate prediction of antibody-antigen (Ab-Ag) binding affinity is essential for therapeutic design and vaccine development, yet the performance of current models is limited by noisy experimental labels, heterogeneous assay conditions, and…

We introduce AbBiBench (Antibody Binding Benchmarking), a benchmarking framework for antibody binding affinity maturation and design. Unlike previous strategies that evaluate antibodies in isolation, typically by comparing them to natural…

The goal of unbiased learning to rank (ULTR) is to leverage implicit user feedback for optimizing learning-to-rank systems. Among existing solutions, automatic ULTR algorithms that jointly learn user bias models (i.e., propensity models)…

List-wise learning to rank methods are considered to be the state-of-the-art. One of the major problems with these methods is that the ambiguous nature of relevance labels in learning to rank data is ignored. Ambiguity of relevance labels…

To obtain a large amount of training labels inexpensively, researchers have recently adopted the weak supervision (WS) paradigm, which leverages labeling rules to synthesize training labels rather than using individual annotations to…

Positive-Unlabeled (PU) learning addresses classification problems where only a subset of positive examples is labeled and the remaining data is unlabeled, making explicit negative supervision unavailable. Existing PU methods often rely on…

Domain shift poses a significant challenge in Cross-Domain Facial Expression Recognition (CD-FER) due to the distribution variation across different domains. Current works mainly focus on learning domain-invariant features through global…

Deep neural networks are highly susceptible to overfitting noisy labels, which leads to degraded performance. Existing methods address this issue by employing manually defined criteria, aiming to achieve optimal partitioning in each…

Antibody-facilitated immune responses are central to the body's defense against pathogens, viruses, and other foreign invaders. The ability of antibodies to specifically bind and neutralize antigens is vital for maintaining immunity. Over…

Pretext Invariant Representation Learning (PIRL) followed by Supervised Fine-Tuning (SFT) has become a standard paradigm for learning with limited labels. We extend this approach to the Positive Unlabeled (PU) setting, where only a small…

Complex data mining has wide application value in many fields, especially in the feature extraction and classification tasks of unlabeled data. This paper proposes an algorithm based on self-supervised learning and verifies its…

Recent strides in large language models (LLMs) have yielded remarkable performance, leveraging reinforcement learning from human feedback (RLHF) to significantly enhance generation and alignment capabilities. However, RLHF encounters…

The primary objective of most lead optimization campaigns is to enhance the binding affinity of ligands. For large molecules such as antibodies, identifying mutations that enhance antibody affinity is particularly challenging due to the…

Unbiased Learning to Rank (ULTR) that learns to rank documents with biased user feedback data is a well-known challenge in information retrieval. Existing methods in unbiased learning to rank typically rely on click modeling or inverse…

Listwise reranking with large language models (LLMs) enhances top-ranked results in retrieval-based applications. Due to the limit in context size and high inference cost of long context, reranking is typically performed over a fixed size…

Document-level relation extraction (RE) aims to identify relations between entities across multiple sentences. Most previous methods focused on document-level RE under full supervision. However, in real-world scenario, it is expensive and…

Alleviating noisy pseudo labels remains a key challenge in Semi-Supervised Temporal Action Localization (SS-TAL). Existing methods often filter pseudo labels based on strict conditions, but they typically assess classification and…

The positive-unlabeled (PU) classification is a common scenario in real-world applications such as healthcare, text classification, and bioinformatics, in which we only observe a few samples labeled as "positive" together with a large…

Self-supervised pretraining on unlabeled data followed by supervised fine-tuning on labeled data is a popular paradigm for learning from limited labeled examples. We extend this paradigm to the classical positive unlabeled (PU) setting,…

Systematic literature reviews (SLRs) are fundamental to evidence-based research, but manual screening is an increasing bottleneck as scientific output grows. Screening features low prevalence of relevant studies and scarce, costly expert…