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The Banff Classification provides the global standard for evaluating renal transplant biopsies, yet its semi-quantitative nature, complex criteria, and inter-observer variability present significant challenges for computational replication.…

计算机视觉与模式识别 · 计算机科学 2025-11-03 Yanfan Zhu , Juming Xiong , Ruining Deng , Yu Wang , Yaohong Wang , Shilin Zhao , Mengmeng Yin , Yuqing Liu , Haichun Yang , Yuankai Huo

Constructing a multi-modal automatic classification model based on three types of renal biopsy images can assist pathologists in glomerular multi-disease identification. However, the substantial scale difference between transmission…

计算机视觉与模式识别 · 计算机科学 2025-12-18 Kaixing Long , Danyi Weng , Yun Mi , Zhentai Zhang , Yanmeng Lu , Jian Geng , Zhitao Zhou , Liming Zhong , Qianjin Feng , Wei Yang , Lei Cao

Multiple sclerosis is an inflammatory autoimmune demyelinating disease that is characterized by lesions in the central nervous system. Typically, magnetic resonance imaging (MRI) is used for tracking disease progression. Automatic image…

图像与视频处理 · 电气工程与系统科学 2020-08-06 Nils Gessert , Julia Krüger , Roland Opfer , Ann-Christin Ostwaldt , Praveena Manogaran , Hagen H. Kitzler , Sven Schippling , Alexander Schlaefer

Whole Slide Images (WSIs) present a challenging computer vision task due to their gigapixel size and presence of numerous artefacts. Yet they are a valuable resource for patient diagnosis and stratification, often representing the gold…

计算机视觉与模式识别 · 计算机科学 2023-10-05 Amaya Gallagher-Syed , Luca Rossi , Felice Rivellese , Costantino Pitzalis , Myles Lewis , Michael Barnes , Gregory Slabaugh

Considerable morphological phenotyping studies in nephrology have emerged in the past few years, aiming to discover hidden regularities between clinical and imaging phenotypes. Such studies have been largely enabled by deep learning based…

图像与视频处理 · 电气工程与系统科学 2020-07-29 Zheyu Zhu , Yuzhe Lu , Ruining Deng , Haichun Yang , Agnes B. Fogo , Yuankai Huo

Systemic lupus erythematosus (SLE) is an autoimmune disease in which the immune system of the patient starts attacking healthy tissues of the body. Lupus Nephritis (LN) refers to the inflammation of kidney tissues resulting in renal failure…

图像与视频处理 · 电气工程与系统科学 2021-12-15 Akash Gupta , Anirudh Reddy , CV Jawahar , PK Vinod

Stain variations often decrease the generalization ability of deep learning based approaches in digital histopathology analysis. Two separate proposals, namely stain normalization (SN) and stain augmentation (SA), have been spotlighted to…

计算机视觉与模式识别 · 计算机科学 2023-03-03 Yiqing Shen , Yulin Luo , Dinggang Shen , Jing Ke

Deep neural networks frequently exploit shortcut features, defined as incidental correlations between inputs and labels without causal meaning. Shortcut features undermine robustness and reduce reliability under distribution shifts. In…

机器学习 · 计算机科学 2025-10-02 Kai Gu , Weishi Shi

The evaluation of white matter lesion progression is an important biomarker in the follow-up of MS patients and plays a crucial role when deciding the course of treatment. Current automated lesion segmentation algorithms are susceptible to…

图像与视频处理 · 电气工程与系统科学 2020-10-28 Mattias Billast , Maria Ines Meyer , Diana M. Sima , David Robben

Segmenting healthy tissue structures alongside lesions in brain Magnetic Resonance Images (MRI) remains a challenge for today's algorithms due to lesion-caused disruption of the anatomy and lack of jointly labeled training datasets, where…

图像与视频处理 · 电气工程与系统科学 2025-03-26 Meva Himmetoglu , Ilja Ciernik , Ender Konukoglu

Recent research has revealed that deep neural networks often take dataset biases as a shortcut to make decisions rather than understand tasks, leading to failures in real-world applications. In this study, we focus on the spurious…

计算与语言 · 计算机科学 2023-06-23 Yanrui Du , Jing Yan , Yan Chen , Jing Liu , Sendong Zhao , Qiaoqiao She , Hua Wu , Haifeng Wang , Bing Qin

The ability of machine learning (ML) classification models to resist small, targeted input perturbations -- known as adversarial attacks -- is a key measure of their safety and reliability. We show that floating-point non-associativity…

Histopathology relies on the analysis of microscopic tissue images to diagnose disease. A crucial part of tissue preparation is staining whereby a dye is used to make the salient tissue components more distinguishable. However, differences…

图像与视频处理 · 电气工程与系统科学 2022-08-03 Haseeb Nazki , Ognjen Arandjelović , InHwa Um , David Harrison

Two DL models were developed using radiograph-level annotations (yes or no disease) and fine-grained lesion-level annotations (lesion bounding boxes), respectively named CheXNet and CheXDet. The models' internal classification performance…

State-of-the-art neural networks are vulnerable to adversarial examples; they can easily misclassify inputs that are imperceptibly different than their training and test data. In this work, we establish that the use of cross-entropy loss…

机器学习 · 计算机科学 2019-01-25 Kamil Nar , Orhan Ocal , S. Shankar Sastry , Kannan Ramchandran

Multimodal contrastive learning methods like CLIP train on noisy and uncurated training datasets. This is cheaper than labeling datasets manually, and even improves out-of-distribution robustness. We show that this practice makes backdoor…

机器学习 · 计算机科学 2022-03-29 Nicholas Carlini , Andreas Terzis

Membranous nephropathy (MN) is a frequent type of adult nephrotic syndrome, which has a high clinical incidence and can cause various complications. In the biopsy microscope slide of membranous nephropathy, spikelike projections on the…

计算机视觉与模式识别 · 计算机科学 2020-07-21 Yilin Chen , Ming Li , Yongfei Wu , Xueyu Liu , Fang Hao , Daoxiang Zhou , Xiaoshuang Zhou , Chen Wang

Histopathological image classification is an important task in medical image analysis. Recent approaches generally rely on weakly supervised learning due to the ease of acquiring case-level labels from pathology reports. However,…

计算机视觉与模式识别 · 计算机科学 2024-11-14 Bodong Zhang , Hamid Manoochehri , Man Minh Ho , Fahimeh Fooladgar , Yosep Chong , Beatrice S. Knudsen , Deepika Sirohi , Tolga Tasdizen

Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…

Ischaemic stroke is a medical condition caused by occlusion of blood supply to the brain tissue thus forming a lesion. A lesion is zoned into a core associated with irreversible necrosis typically located at the center of the lesion, while…

图像与视频处理 · 电气工程与系统科学 2019-08-06 Rachana Sathish , Ronnie Rajan , Anusha Vupputuri , Nirmalya Ghosh , Debdoot Sheet