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LLMs for clinical decision support often fail under small but clinically meaningful input shifts such as masking a symptom or negating a finding, despite high performance on static benchmarks. These reasoning failures frequently go…

机器学习 · 计算机科学 2025-07-30 Raj Krishnan Vijayaraj

The development of large language models (LLMs) has brought unprecedented possibilities for artificial intelligence (AI) based medical diagnosis. However, the application perspective of LLMs in real diagnostic scenarios is still unclear…

计算与语言 · 计算机科学 2024-05-21 Zhoujian Sun , Cheng Luo , Ziyi Liu , Zhengxing Huang

Automatic diagnosis is a significant application of AI in healthcare, where diagnoses are generated based on the symptom description of patients. Previous works have approached this task directly by modeling the relationship between the…

计算与语言 · 计算机科学 2024-01-30 Haochun Wang , Sendong Zhao , Zewen Qiang , Nuwa Xi , Bing Qin , Ting Liu

Cognitive Diagnosis Models (CDMs) are a special family of discrete latent variable models that are widely used in modern educational, psychological, social and biological sciences. A key component of CDMs is a binary $Q$-matrix…

统计方法学 · 统计学 2025-01-08 Chenchen Ma , Gongjun Xu

Machine reasoning has made great progress in recent years owing to large language models (LLMs). In the clinical domain, however, most NLP-driven projects mainly focus on clinical classification or reading comprehension, and under-explore…

Recently computer-aided diagnosis has demonstrated promising performance, effectively alleviating the workload of clinicians. However, the inherent sample imbalance among different diseases leads algorithms biased to the majority…

计算机视觉与模式识别 · 计算机科学 2025-02-10 Li Pan , Yupei Zhang , Qiushi Yang , Tan Li , Zhen Chen

The existing methods for evaluating the medical knowledge of Large Language Models (LLMs) are largely based on atemporal examination-style benchmarks, while in reality, medical knowledge is inherently dynamic and continuously evolves as new…

机器学习 · 计算机科学 2026-05-14 Zihan Guan , Qiao Jin , Guangzhi Xiong , Fangyuan Chen , Mengxuan Hu , Qingyu Chen , Yifan Peng , Zhiyong Lu , Anil Vullikanti

We propose a clinical decision support system (CDSS) for mental health diagnosis that combines the strengths of large language models (LLMs) and constraint logic programming (CLP). Having a CDSS is important because of the high complexity…

人工智能 · 计算机科学 2025-02-24 Brian Hyeongseok Kim , Chao Wang

Label Distribution Learning (LDL) is an effective approach for handling label ambiguity, as it can analyze all labels at once and indicate the extent to which each label describes a given sample. Most existing LDL methods consider the…

机器学习 · 计算机科学 2024-11-21 Ziqi Jia , Xiaoyang Qu , Chenghao Liu , Jianzong Wang

The complexity and heterogeneity of data in many real-world applications pose significant challenges for traditional machine learning and signal processing techniques. For instance, in medicine, effective analysis of diverse physiological…

机器学习 · 计算机科学 2024-08-16 Nimeesha Chan , Felix Parker , William Bennett , Tianyi Wu , Mung Yao Jia , James Fackler , Kimia Ghobadi

Large language models (LLMs) show promise for extracting clinically meaningful information from unstructured health records, yet their translation into real-world settings is constrained by the lack of scalable and trustworthy validation…

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

LLM-based agents have emerged as transformative tools capable of executing complex tasks through iterative planning and action, achieving significant advancements in understanding and addressing user needs. Yet, their effectiveness remains…

人机交互 · 计算机科学 2025-08-26 Mithat Can Ozgun , Jiahuan Pei , Koen Hindriks , Lucia Donatelli , Qingzhi Liu , Junxiao Wang

Label distribution learning (LDL) is a general learning framework, which assigns to an instance a distribution over a set of labels rather than a single label or multiple labels. Current LDL methods have either restricted assumptions on the…

机器学习 · 计算机科学 2017-10-18 Wei Shen , Kai Zhao , Yilu Guo , Alan Yuille

Large language models (LLMs) show promise for diagnostic reasoning but often lack reliable, knowledge grounded inference. Knowledge graphs (KGs), such as the Unified Medical Language System (UMLS), offer structured biomedical knowledge that…

计算与语言 · 计算机科学 2025-09-24 Saksham Khatwani , He Cheng , Majid Afshar , Dmitriy Dligach , Yanjun Gao

This paper focuses on extending the success of large language models (LLMs) to sequential decision making. Existing efforts either (i) re-train or finetune LLMs for decision making, or (ii) design prompts for pretrained LLMs. The former…

机器学习 · 计算机科学 2025-06-17 Dingyang Chen , Qi Zhang , Yinglun Zhu

Large language models (LLMs) often achieve impressive predictive accuracy, yet correctness alone does not imply genuine understanding. True LLM understanding, analogous to human expertise, requires making consistent, well-founded decisions…

计算与语言 · 计算机科学 2025-11-17 Sichao Li , Xinyue Xu , Xiaomeng Li

Diffusion Language Models (DLMs) offer a promising parallel generation paradigm but suffer from slow inference due to numerous refinement steps and the inability to use standard KV caching. We introduce CDLM (Consistency Diffusion Language…

机器学习 · 计算机科学 2026-02-23 Minseo Kim , Chenfeng Xu , Coleman Hooper , Harman Singh , Ben Athiwaratkun , Ce Zhang , Kurt Keutzer , Amir Gholami

Despite the wide adoption of Large Language Models (LLM)s, clinical decision support systems face a critical challenge: achieving high predictive accuracy while generating explanations aligned with the predictions. Current approaches suffer…

人工智能 · 计算机科学 2026-05-07 H M Quamran Hasan , Housam Khalifa Bashier , Jiayi Dai , Mi-Young Kim , Randy Goebel

The field of lung nodule detection and cancer prediction has been rapidly developing with the support of large public data archives. Previous studies have largely focused on cross-sectional (single) CT data. Herein, we consider longitudinal…