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Magnetic Resonance Spectroscopic Imaging (MRSI) is a valuable tool for studying metabolic activities in the human body, but the current applications are limited to low spatial resolutions. The existing deep learning-based MRSI…

图像与视频处理 · 电气工程与系统科学 2022-06-22 Siyuan Dong , Gilbert Hangel , Wolfgang Bogner , Georg Widhalm , Karl Rössler , Siegfried Trattnig , Chenyu You , Robin de Graaf , John Onofrey , James Duncan

Magnetic resonance spectroscopic imaging (MRSI) enables the simultaneous non-invasive acquisition of MR spectra from multiple spatial locations inside the brain. While 1H-MRSI is increasingly used in the human brain, it is not yet widely…

Magnetic Resonance Spectroscopic Imaging (MRSI) is a clinical imaging modality for measuring tissue metabolite levels in-vivo. An accurate estimation of spectral parameters allows for better assessment of spectral quality and metabolite…

计算机视觉与模式识别 · 计算机科学 2018-05-28 Dhritiman Das , Eduardo Coello , Rolf F Schulte , Bjoern H Menze

Whole-brain proton magnetic resonance spectroscopic imaging (1H-MRSI) is a non-invasive technique for assessing neurochemical distribution in the brain, offering valuable insights into brain functions and neural diseases. It greatly…

医学物理 · 物理学 2024-10-08 Zhiwei Huang , Uzay Emir , Andre Doring , Antoine Klauser , Ying Xiao , Mark Widmaier , Lijing Xin

Purpose: Magnetic Resonance Spectroscopic Imaging (MRSI) maps endogenous brain metabolism while suppressing the overwhelming water signal. Water-unsuppressed MRSI (wu-MRSI) allows simultaneous imaging of water and metabolites, but large…

图像与视频处理 · 电气工程与系统科学 2025-12-18 Paul J. Weiser , Jiye Kim , Jongho Lee , Amirmohammad Shamaei , Gulnur Ungan , Malte Hoffmann , Antoine Klauser , Berkin Bilgic , Ovidiu C. Andronesi

Magnetic resonance spectroscopy (MRS) is an important technique in biomedical research and it has the unique capability to give a non-invasive access to the biochemical content (metabolites) of scanned organs. In the literature, the…

计算机视觉与模式识别 · 计算机科学 2018-06-20 Nima Hatami , Michaël Sdika , Hélène Ratiney

Purpose. Proton Magnetic Resonance Spectroscopic Imaging (1H-MRSI) provides non-invasive spectral-spatial mapping of metabolism. However, long-standing problems in whole-brain 1H-MRSI are spectral overlap of metabolite peaks with large…

图像与视频处理 · 电气工程与系统科学 2025-12-16 Paul Weiser , Georg Langs , Stanislav Motyka , Wolfgang Bogner , Sébastien Courvoisier , Malte Hoffmann , Antoine Klauser , Ovidiu C. Andronesi

Introduction: Altered neurometabolism is an important pathological mechanism in many neurological diseases and brain cancer, which can be mapped non-invasively by Magnetic Resonance Spectroscopic Imaging (MRSI). Advanced MRSI using…

Objective: Magnetic Resonance Spectroscopy (MRS) is an important technique for biomedical detection. However, it is challenging to accurately quantify metabolites with proton MRS due to serious overlaps of metabolite signals, imperfections…

Biophysical model fitting plays a key role in obtaining quantitative parameters from physiological signals and images. However, the model complexity for molecular magnetic resonance imaging (MRI) often translates into excessive computation…

医学物理 · 物理学 2025-04-18 Alex Finkelstein , Nikita Vladimirov , Moritz Zaiss , Or Perlman

MR experiments are essential for studying brain metabolism, yet preclinical 1H-MRSI remains underdeveloped, with significant limitations in SNR, acquisition speed, and automated data processing. Although recent advances-such as accelerated…

Many diseases cause significant changes to the concentrations of small molecules (aka metabolites) that appear in a person's biofluids, which means such diseases can often be readily detected from a person's "metabolic profile". This…

Overfitting is defined as the fact that the current model fits a specific data set perfectly, resulting in weakened generalization, and ultimately may affect the accuracy in predicting future data. In this research we used an EHR dataset…

机器学习 · 计算机科学 2022-08-04 Chuhan Xu , Pablo Coen-Pirani , Xia Jiang

Quantification of metabolites from magnetic resonance spectra (MRS) has many applications in medicine and psychology, but remains a challenging task despite considerable research efforts. For example, the neurotransmitter…

图像与视频处理 · 电气工程与系统科学 2019-09-10 M. Chandler , C. Jenkins , S. M. Shermer , F. C. Langbein

Model compression is vital to the deployment of deep learning on edge devices. Low precision representations, achieved via quantization of weights and activations, can reduce inference time and memory requirements. However, quantifying and…

机器学习 · 计算机科学 2022-10-18 Ben Zandonati , Adrian Alan Pol , Maurizio Pierini , Olya Sirkin , Tal Kopetz

Magnetic Resonance Spectroscopy (MRS) is a noninvasive tool to reveal metabolic information. One challenge of 1H-MRS is the low Signal-Noise Ratio (SNR). To improve the SNR, a typical approach is to perform Signal Averaging (SA) with M…

Since the publication of our review article Hyperspectral imaging solutions for brain tissue metabolic and hemodynamic monitoring: past, current and future developments in 2018, the technological and applicational landscape of the use of…

医学物理 · 物理学 2026-03-24 Luca Giannoni , Frédéric Lange , Ilias Tachtsidis

High-spatial-resolution hyperspectral images (HSI) are essential for applications such as remote sensing and medical imaging, yet HSI sensors inherently trade spatial detail for spectral richness. Fusing high-spatial-resolution…

图像与视频处理 · 电气工程与系统科学 2026-05-22 Ritik Shah , Marco F. Duarte

Hypernetworks, neural networks that predict the parameters of another neural network, are powerful models that have been successfully used in diverse applications from image generation to multi-task learning. Unfortunately, existing…

机器学习 · 计算机科学 2023-06-30 Jose Javier Gonzalez Ortiz , John Guttag , Adrian Dalca

Untargeted metabolomics using LC-MS/MS offers the potential to comprehensively profile the chemical diversity of biological samples. However, the process is fundamentally limited by the "identification bottleneck," where only a small…

定量方法 · 定量生物学 2025-10-14 Hansol Hong , Sangwon Lee , Jang-Ho Ha , Sung-June Chu , So-Hee An , Woo-Hyun Paek , Gyuhwa Chung , Kyoung Tai No
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