相关论文: Harmonization mitigates diffusion MRI scanner effe…
Multi-site structural MRI is increasingly used in neuroimaging studies to diversify subject cohorts. However, combining MR images acquired from various sites/centers may introduce site-related non-biological variations. Retrospective image…
Diffusion-weighted magnetic resonance imaging (DW-MRI) derived scalar maps are effective for assessing neurodegenerative diseases and microstructural properties of white matter in large number of brain conditions. However, DW-MRI inherently…
Diffusion imaging is an important method in the field of neuroscience, as it is sensitive to changes within the tissue microstructure of the human brain. However, a major challenge when using MRI to derive quantitative measures is that the…
Diffusion magnetic resonance imaging is a noninvasive imaging technique that can indirectly infer the microstructure of tissues and provide metrics which are subject to normal variability across subjects. Potentially abnormal values or…
Pooling publicly-available MRI data from multiple sites allows to assemble extensive groups of subjects, increase statistical power, and promote data reuse with machine learning techniques. The harmonization of multicenter data is necessary…
Harmonization methods such as ComBat and its variants are widely used to mitigate diffusion MRI (dMRI) site-specific biases. However, ComBat assumes that subject distributions exhibit a Gaussian profile. In practice, patients with…
Connectivity matrices derived from diffusion MRI (dMRI) provide an interpretable and generalizable way of understanding the human brain connectome. However, dMRI suffers from inter-site and between-scanner variation, which impedes analysis…
A major data pre-processing step for large, multi-site studies is to handle site effects by harmonizing data, generating a dataset that enables more powerful analyses and more robust algorithms. There is a wide variety of data harmonization…
Magnetic resonance (MR) images from multiple sources often show differences in image contrast related to acquisition settings or the used scanner type. For long-term studies, longitudinal comparability is essential but can be impaired by…
Over the years, ComBAT has become the standard method for harmonizing MRI-derived measurements, with its ability to compensate for site-related additive and multiplicative biases while preserving biological variability. However, ComBAT…
Multi-center neuroimaging studies face technical variability due to batch differences across sites, which potentially hinders data aggregation and impacts study reliability.Recent efforts in neuroimaging harmonization have aimed to minimize…
Removing the bias and variance of multicentre data has always been a challenge in large scale digital healthcare studies, which requires the ability to integrate clinical features extracted from data acquired by different scanners and…
In MRI, variations in scan parameters, sequence, or hardware can lead to discrepancies in image appearance, even for the same subject. These inconsistencies, known as domain shifts, can hinder image analysis and degrade the performance of…
White matter alterations are increasingly implicated in neurological diseases and their progression. International-scale studies use diffusion-weighted magnetic resonance imaging (DW-MRI) to qualitatively identify changes in white matter…
Magnetic resonance imaging (MRI) is an invaluable tool for clinical and research applications. Yet, variations in scanners and acquisition parameters cause inconsistencies in image contrast, hindering data comparability and reproducibility…
Purpose: In the present work we describe the correction of diffusion-weighted MRI for site and scanner biases using a novel method based on invariant representation. Theory and Methods: Pooled imaging data from multiple sources are subject…
Independent and identically distributed (i.i.d.) data is essential to many data analysis and modeling techniques. In the medical domain, collecting data from multiple sites or institutions is a common strategy that guarantees sufficient…
Magnetic resonance imaging (MRI) has greatly advanced neuroscience research and clinical diagnostics. However, imaging data collected across different scanners, acquisition protocols, or imaging sites often exhibit substantial…
Purpose: Combining multi-site diffusion MRI (dMRI) data is hindered by inter-scanner variability, which confounds subsequent analysis. Previous harmonization methods require large, matched or traveling human subjects from multiple sites,…
The ability to combine data across scanners and studies is vital for neuroimaging, to increase both statistical power and the representation of biological variability. However, combining datasets across sites leads to two challenges: first,…