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How does the human brain encode complex visual information? While previous research has characterized individual dimensions of visual representation in cortex, we still lack a comprehensive understanding of how visual information is…

神经元与认知 · 定量生物学 2026-04-08 Raj Magesh Gauthaman , Brice Ménard , Michael F. Bonner

Brain foundation models (BFMs) have emerged as a transformative paradigm in computational neuroscience, offering a revolutionary framework for processing diverse neural signals across different brain-related tasks. These models leverage…

机器学习 · 计算机科学 2025-07-22 Xinliang Zhou , Chenyu Liu , Zhisheng Chen , Kun Wang , Yi Ding , Ziyu Jia , Qingsong Wen

Foundation models have transformed vision and language by learning general-purpose representations from large-scale unlabeled data, yet 3D medical imaging lacks analogous approaches. Existing self-supervised methods rely on low-level…

计算机视觉与模式识别 · 计算机科学 2026-03-17 Yunhe Gao , Yabin Zhang , Chong Wang , Jiaming Liu , Maya Varma , Jean-Benoit Delbrouck , Akshay Chaudhari , Curtis Langlotz

If we are ever to unravel the mysteries of brain function at its most fundamental level, we will need a precise understanding of how its component neurons connect to each other. Electron Microscopes (EM) can now provide the nanometer…

计算机视觉与模式识别 · 计算机科学 2016-09-28 Pascal Fua , Graham Knott

Whole-brain neural connectivity data are now available from viral tracing experiments, which reveal the connections between a source injection site and elsewhere in the brain. These hold the promise of revealing spatial patterns of…

神经元与认知 · 定量生物学 2016-10-27 Kameron Decker Harris , Stefan Mihalas , Eric Shea-Brown

Recent neuroimaging studies that focus on predicting brain disorders via modern machine learning approaches commonly include a single modality and rely on supervised over-parameterized models.However, a single modality provides only a…

Transformers have demonstrated remarkable performance in natural language processing and computer vision. However, existing vision Transformers struggle to learn from limited medical data and are unable to generalize on diverse medical…

图像与视频处理 · 电气工程与系统科学 2023-04-06 Yunhe Gao , Mu Zhou , Di Liu , Zhennan Yan , Shaoting Zhang , Dimitris N. Metaxas

Optical imaging of the brain has expanded dramatically in the past two decades. New optics, indicators, and experimental paradigms are now enabling in-vivo imaging from the synaptic to the cortex-wide scales. To match the resulting flood of…

图像与视频处理 · 电气工程与系统科学 2024-02-15 Gal Mishne , Adam Charles

Learning meaningful and interpretable representations from high-dimensional volumetric magnetic resonance (MR) images is essential for advancing personalized medicine. While Vision Transformers (ViTs) have shown promise in handling image…

计算机视觉与模式识别 · 计算机科学 2024-09-13 Qingqiao Hu , Daoan Zhang , Jiebo Luo , Zhenyu Gong , Benedikt Wiestler , Jianguo Zhang , Hongwei Bran Li

A central problem in neuroscience is reconstructing neuronal circuits on the synapse level. Due to a wide range of scales in brain architecture such reconstruction requires imaging that is both high-resolution and high-throughput. Existing…

计算机视觉与模式识别 · 计算机科学 2012-10-03 Tao Hu , Juan Nunez-Iglesias , Shiv Vitaladevuni , Lou Scheffer , Shan Xu , Mehdi Bolorizadeh , Harald Hess , Richard Fetter , Dmitri Chklovskii

Deep neural networks have brought remarkable breakthroughs in medical image analysis. However, due to their data-hungry nature, the modest dataset sizes in medical imaging projects might be hindering their full potential. Generating…

Whole brain segmentation with magnetic resonance imaging (MRI) enables the non-invasive measurement of brain regions, including total intracranial volume (TICV) and posterior fossa volume (PFV). Enhancing the existing whole brain…

图像与视频处理 · 电气工程与系统科学 2024-04-24 Xin Yu , Yucheng Tang , Qi Yang , Ho Hin Lee , Shunxing Bao , Yuankai Huo , Bennett A. Landman

Neuroimaging data, particularly from techniques like MRI or PET, offer rich but complex information about brain structure and activity. To manage this complexity, latent representation models - such as Autoencoders, Generative Adversarial…

计算机视觉与模式识别 · 计算机科学 2024-12-31 C. Vázquez-García , F. J. Martínez-Murcia , F. Segovia Román , Juan M. Górriz

Contemporary computational neuroscience features two prominent modeling traditions. Bottom-up whole-brain modeling (WBM) builds biophysically detailed simulations of brain structure and dynamics, whereas top-down neuroconnectionism…

神经元与认知 · 定量生物学 2026-05-19 Mario Senden , Leonardo Dalla Porta , Jan Fousek , Jorge F. Mejias , Gorka Zamora-López

This paper presents an annotated dataset of brain MRI images designed to advance the field of brain symmetry study. Magnetic resonance imaging (MRI) has gained interest in analyzing brain symmetry in neonatal infants, and challenges remain…

计算机视觉与模式识别 · 计算机科学 2024-01-23 Arnaud Gucciardi , Safouane El Ghazouali , Francesca Venturini , Vida Groznik , Umberto Michelucci

The rapid development in information technology has immensely contributed to the use of modern approaches for visualizing volumetric data. Consequently, medical volume visualization is increasingly attracting attention towards achieving an…

计算几何 · 计算机科学 2012-11-27 A. M. Adeshina , R. Hashim , N. E. A. Khalid , Siti Z. Z. Abidin

Reconstructing human vision from brain activities has been an appealing task that helps to understand our cognitive process. Even though recent research has seen great success in reconstructing static images from non-invasive brain…

计算机视觉与模式识别 · 计算机科学 2023-05-22 Zijiao Chen , Jiaxin Qing , Juan Helen Zhou

Foundation models (FMs) are transforming computational pathology by offering new ways to analyze histopathology images. However, FMs typically require weeks of training on large databases, making their creation a resource-intensive process.…

图像与视频处理 · 电气工程与系统科学 2026-01-27 Till Nicke , Daniela Schacherer , Jan Raphael Schäfer , Natalia Artysh , Antje Prasse , André Homeyer , Andrea Schenk , Henning Höfener , Johannes Lotz

Tensor-based morphometry (TBM) aims at showing local differences in brain volumes with respect to a common template. TBM images are smooth but they exhibit (especially in diseased groups) higher values in some brain regions called lateral…

The connectome, a map of the structural and/or functional connections in the brain, provides a complex representation of the neurobiological phenotypes on which it supervenes. This information-rich data modality has the potential to…