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Learning electronic health records (EHRs) has received emerging attention because of its capability to facilitate accurate medical diagnosis. Since the EHRs contain enriched information specifying complex interactions between entities,…

机器学习 · 计算机科学 2024-08-15 Tsai Hor Chan , Guosheng Yin , Kyongtae Bae , Lequan Yu

We propose RareGraph-Synth, a knowledge-guided, continuous-time diffusion framework that generates realistic yet privacy-preserving synthetic electronic-health-record (EHR) trajectories for ultra-rare diseases. RareGraph-Synth unifies five…

机器学习 · 计算机科学 2025-10-09 Khartik Uppalapati , Shakeel Abdulkareem , Bora Yimenicioglu

The integration of multimodal Electronic Health Records (EHR) data has significantly advanced clinical predictive capabilities. Existing models, which utilize clinical notes and multivariate time-series EHR data, often fall short of…

计算与语言 · 计算机科学 2025-02-27 Yinghao Zhu , Changyu Ren , Zixiang Wang , Xiaochen Zheng , Shiyun Xie , Junlan Feng , Xi Zhu , Zhoujun Li , Liantao Ma , Chengwei Pan

The introduction of electronic personal health records (EHR) enables nationwide information exchange and curation among different health care systems. However, the current EHR systems do not provide transparent means for diagnosis support,…

分布式、并行与集群计算 · 计算机科学 2022-10-04 Dragi Kimovski , Sasko Ristov , Radu Prodan

Electronic Health Records (EHRs) contain extensive patient information that can inform downstream clinical decisions, such as mortality prediction, disease phenotyping, and disease onset prediction. A key challenge in EHR data analysis is…

应用统计 · 统计学 2026-01-01 Xin Gai , Shiyi Jiang , Anru R. Zhang

Longitudinal multimodal data, including electronic health records (EHR) and sequential chest X-rays (CXRs), is critical for modeling disease progression, yet remains underutilized due to two key challenges: (1) redundancy in consecutive CXR…

计算机视觉与模式识别 · 计算机科学 2025-10-14 Chen Liu , Wenfang Yao , Kejing Yin , William K. Cheung , Jing Qin

Analysis of longitudinal Electronic Health Record (EHR) data is an important goal for precision medicine. Difficulty in applying Machine Learning (ML) methods, either predictive or unsupervised, stems in part from the heterogeneity and…

In electronic health records (EHRs), clustering patients and distinguishing disease subtypes are key tasks to elucidate pathophysiology and aid clinical decision-making. However, clustering in healthcare informatics is still based on…

机器学习 · 计算机科学 2026-04-09 Manar D. Samad , Yina Hou , Shrabani Ghosh

Integrating multimodal Electronic Health Records (EHR) data, such as numerical time series and free-text clinical reports, has great potential in predicting clinical outcomes. However, prior work has primarily focused on capturing temporal…

机器学习 · 计算机科学 2025-11-10 Fuying Wang , Feng Wu , Yihan Tang , Lequan Yu

Chest X-ray (CXR) is an important diagnostic tool widely used in hospitals to assess patient conditions and monitor changes over time. Recently, generative models, specifically diffusion-based models, have shown promise in generating…

图像与视频处理 · 电气工程与系统科学 2025-05-07 Daeun Kyung , Junu Kim , Tackeun Kim , Edward Choi

Deep learning in cardiac MRI (CMR) is fundamentally constrained by both data scarcity and privacy regulations. This study systematically benchmarks three generative architectures: Denoising Diffusion Probabilistic Models (DDPM), Latent…

计算机视觉与模式识别 · 计算机科学 2026-03-05 Madhura Edirisooriya , Dasuni Kawya , Ishan Kumarasinghe , Isuri Devindi , Mary M. Maleckar , Roshan Ragel , Isuru Nawinne , Vajira Thambawita

Healthcare is becoming a more and more important research topic recently. With the growing data in the healthcare domain, it offers a great opportunity for deep learning to improve the quality of medical service. However, the complexity of…

计算与语言 · 计算机科学 2021-11-01 Bo Yang , Lijun Wu

The present study introduces an innovative approach to the synthesis of Electroencephalogram (EEG) signals by integrating diffusion models with reinforcement learning. This integration addresses key challenges associated with traditional…

信号处理 · 电气工程与系统科学 2024-10-02 Yang An , Yuhao Tong , Weikai Wang , Steven W. Su

Clinical time series derived from electronic health records (EHRs) are inherently irregular, with asynchronous sampling, missing values, and heterogeneous feature dynamics. While numerical laboratory measurements are highly informative,…

人工智能 · 计算机科学 2025-11-13 Yi-Hsien Hsieh , Ta-Jung Chien , Chun-Kai Huang , Shao-Hua Sun , Che Lin

Data scarcity in the brain-computer interface field can be alleviated through the use of generative models, specifically diffusion models. While diffusion models have previously been successfully applied to electroencephalogram (EEG) data,…

机器学习 · 计算机科学 2024-11-05 Guido Klein , Pierre Guetschel , Gianluigi Silvestri , Michael Tangermann

The wide adoption of Electronic Health Records (EHR) has resulted in large amounts of clinical data becoming available, which promises to support service delivery and advance clinical and informatics research. Deep learning techniques have…

机器学习 · 计算机科学 2022-02-14 Thanh Nguyen-Duc , Natasha Mulligan , Gurdeep S. Mannu , Joao H. Bettencourt-Silva

The limited data availability due to strict privacy regulations and significant resource demands severely constrains biomedical time-series AI development, which creates a critical gap between data requirements and accessibility. Synthetic…

机器学习 · 计算机科学 2025-11-25 Youngjoon Lee , Seongmin Cho , Yehhyun Jo , Jinu Gong , Hyunjoo Jenny Lee , Joonhyuk Kang

This study proposes a Transformer-based longitudinal modeling method to address challenges in clinical risk classification with heterogeneous Electronic Health Record (EHR) data, including irregular temporal patterns, large modality…

机器学习 · 计算机科学 2025-11-07 Anzhuo Xie , Wei-Chen Chang

This study proposes a risk prediction method based on a Multi-Scale Temporal Alignment Network (MSTAN) to address the challenges of temporal irregularity, sampling interval differences, and multi-scale dynamic dependencies in Electronic…

机器学习 · 计算机科学 2025-11-27 Wei-Chen Chang , Lu Dai , Ting Xu

Research is a tertiary priority in the EHR, where the priorities are patient care and billing. Because of this, the data is not standardized or formatted in a manner easily adapted to machine learning approaches. Data may be missing for a…

机器学习 · 计算机科学 2017-07-25 Brett K. Beaulieu-Jones