中文
相关论文

相关论文: Multimodal Model for Computational Pathology:Repre…

200 篇论文

Recent advances in whole slide imaging (WSI) technology have led to the development of a myriad of computer vision and artificial intelligence (AI) based diagnostic, prognostic, and predictive algorithms. Computational Pathology (CPath)…

Diagnosing diseases through histopathology whole slide images (WSIs) is fundamental in modern pathology but is challenged by the gigapixel scale and complexity of WSIs. Trained histopathologists overcome this challenge by navigating the…

Multiple Instance Learning (MIL) methods allow for gigapixel Whole-Slide Image (WSI) analysis with only slide-level annotations. Interpretability is crucial for safely deploying such algorithms in high-stakes medical domains. Traditional…

计算机视觉与模式识别 · 计算机科学 2025-01-07 Susu Sun , Leslie Tessier , Frédérique Meeuwsen , Clément Grisi , Dominique van Midden , Geert Litjens , Christian F. Baumgartner

The interpretation of histopathology cases underlies many important diagnostic and treatment decisions in medicine. Notably, this process typically requires pathologists to integrate and summarize findings across multiple slides per case.…

Representation learning of pathology whole-slide images (WSIs) has been has primarily relied on weak supervision with Multiple Instance Learning (MIL). However, the slide representations resulting from this approach are highly tailored to…

计算机视觉与模式识别 · 计算机科学 2024-05-21 Andrew H. Song , Richard J. Chen , Tong Ding , Drew F. K. Williamson , Guillaume Jaume , Faisal Mahmood

Despite remarkable efforts been made, the classification of gigapixels whole-slide image (WSI) is severely restrained from either the constrained computing resources for the whole slides, or limited utilizing of the knowledge from different…

计算机视觉与模式识别 · 计算机科学 2022-07-13 Ming Feng , Kele Xu , Nanhui Wu , Weiquan Huang , Yan Bai , Changjian Wang , Huaimin Wang

Developing self-supervised learning (SSL) models that can learn universal and transferable representations of H&E gigapixel whole-slide images (WSIs) is becoming increasingly valuable in computational pathology. These models hold the…

图像与视频处理 · 电气工程与系统科学 2024-08-07 Guillaume Jaume , Anurag Vaidya , Andrew Zhang , Andrew H. Song , Richard J. Chen , Sharifa Sahai , Dandan Mo , Emilio Madrigal , Long Phi Le , Faisal Mahmood

Tissue phenotyping is a fundamental task in learning objective characterizations of histopathologic biomarkers within the tumor-immune microenvironment in cancer pathology. However, whole-slide imaging (WSI) is a complex computer vision in…

计算机视觉与模式识别 · 计算机科学 2022-03-02 Richard J. Chen , Rahul G. Krishnan

Accurate survival prediction from histopathology whole-slide images (WSIs) remains challenging due to their gigapixel resolution, strong spatial heterogeneity, and complex survival distributions. We introduce a comprehensive computational…

计算机视觉与模式识别 · 计算机科学 2025-11-18 Ardhendu Sekhar , Vasu Soni , Keshav Aske , Shivam Madnoorkar , Pranav Jeevan , Amit Sethi

Traditional whole slide image (WSI) analysis methods typically rely on the multiple instance learning (MIL) paradigm, which extracts patch-level features at high magnification and aggregates them for slide-level prediction. However, such…

Multimodal machine learning integrating histopathology and molecular data shows promise for cancer prognostication. We systematically reviewed studies combining whole slide images (WSIs) and high-throughput omics to predict overall…

定量方法 · 定量生物学 2025-07-30 Charlotte Jennings , Andrew Broad , Lucy Godson , Emily Clarke , David Westhead , Darren Treanor

Non-invasive brain imaging techniques allow understanding the behavior and macro changes in the brain to determine the progress of a disease. However, computational pathology provides a deeper understanding of brain disorders at cellular…

图像与视频处理 · 电气工程与系统科学 2023-01-18 Gabriel Jimenez , Daniel Racoceanu

A Whole Slide Image (WSI) is a high-resolution digital image created by scanning an entire glass slide containing a biological specimen, such as tissue sections or cell samples, at multiple magnifications. These images are digitally…

Recent advancements in Digital Pathology (DP), particularly through artificial intelligence and Foundation Models, have underscored the importance of large-scale, diverse, and richly annotated datasets. Despite their critical role, publicly…

图像与视频处理 · 电气工程与系统科学 2025-05-20 Dmitry Nechaev , Alexey Pchelnikov , Ekaterina Ivanova

Multiple Instance Learning (MIL) and transformers are increasingly popular in histopathology Whole Slide Image (WSI) classification. However, unlike human pathologists who selectively observe specific regions of histopathology tissues under…

计算机视觉与模式识别 · 计算机科学 2023-07-18 Conghao Xiong , Hao Chen , Joseph J. Y. Sung , Irwin King

Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…

计算机视觉与模式识别 · 计算机科学 2022-09-28 Jingwei Zhang , Xin Zhang , Ke Ma , Rajarsi Gupta , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

We developed a software pipeline for quality control (QC) of histopathology whole slide images (WSIs) that segments various regions, such as blurs of different levels, tissue regions, tissue folds, and pen marks. Given the necessity and…

图像与视频处理 · 电气工程与系统科学 2025-06-17 Abhijeet Patil , Garima Jain , Harsh Diwakar , Jay Sawant , Tripti Bameta , Swapnil Rane , Amit Sethi

Accurate prediction of placental diseases via whole slide images (WSIs) is critical for preventing severe maternal and fetal complications. However, WSI analysis presents significant computational challenges due to the massive data volume.…

计算机视觉与模式识别 · 计算机科学 2025-08-06 Hang Guo , Qing Zhang , Zixuan Gao , Siyuan Yang , Shulin Peng , Xiang Tao , Ting Yu , Yan Wang , Qingli Li

Integrating whole-slide images (WSIs) and bulk transcriptomics for predicting patient survival can improve our understanding of patient prognosis. However, this multimodal task is particularly challenging due to the different nature of…

计算机视觉与模式识别 · 计算机科学 2024-04-16 Guillaume Jaume , Anurag Vaidya , Richard Chen , Drew Williamson , Paul Liang , Faisal Mahmood

Histopathology images; microscopy images of stained tissue biopsies contain fundamental prognostic information that forms the foundation of pathological analysis and diagnostic medicine. However, diagnostics from histopathology images…

计算机视觉与模式识别 · 计算机科学 2019-10-30 Aïcha BenTaieb , Ghassan Hamarneh