相关论文: Hippocampus mediates conceptual generalization of …
EEG-based analysis of pain perception, enhanced by machine learning, reveals how the brain encodes pain by identifying neural patterns evoked by noxious stimulation. However, a major challenge that remains is the generalization of machine…
Pain is a multidimensional process, which can be modulated by emotions, however, the mechanisms underlying this modulation are unknown. We used pictures with different emotional valence (negative, positive, neutral) as primes and applied…
Neuroimaging data allows researchers to model the relationship between multivariate patterns of brain activity and outcomes related to mental states and behaviors. However, the existence of outlying participants can potentially undermine…
Pain is among the most salient of experiences while also, curiously, being among the most malleable. A large body of research has revealed that a multitude of explicit strategies can be used to effectively alter the attention-demanding…
Chronic pain is recognized as a major health problem, with impacts not only at the economic, but also at the social, and individual levels. Being a private and subjective experience, it is impossible to externally and impartially…
The focus of the efforts for defining and modelling emotion is broadly shifting from classical definite marker theory to statistically context situated conceptual theory. However, the role of context processing and its interaction with the…
Chronic pain is a multi-dimensional experience, and pain intensity plays an important part, impacting the patients emotional balance, psychology, and behaviour. Standard self-reporting tools, such as the Visual Analogue Scale for pain, fail…
Understanding how neural dynamics shape cognitive experiences remains a central challenge in neuroscience and psychiatry. Here, we present a novel framework leveraging state-to-output controllability from dynamical systems theory to model…
Psychological studies observe that emotions are rarely expressed in isolation and are typically influenced by the surrounding context. While recent studies effectively harness uni- and multimodal cues for emotion inference, hardly any study…
Studying psychiatric illness has often been limited by difficulties in connecting symptoms and behavior to neurobiology. Computational psychiatry approaches promise to bridge this gap by providing formal accounts of the latent information…
The neural implementation of operant conditioning with few trials is unclear. We propose a Hippocampus-Inspired Cognitive Architecture (HICA) as a neural mechanism for operant conditioning. HICA explains a learning mechanism in which agents…
Chronic pain affects about 100 million adults in the US. Despite their great need, neuropharmacology and neurostimulation therapies for chronic pain have been associated with suboptimal efficacy and limited long-term success, as their…
The ability to modulate brain states using targeted stimulation is increasingly being employed to treat neurological disorders and to enhance human performance. Despite the growing interest in brain stimulation as a form of neuromodulation,…
Humans readily generalize, applying prior knowledge to novel situations and stimuli. Advances in machine learning and artificial intelligence have begun to approximate and even surpass human performance, but machine systems reliably…
To study information processing in the brain, neuroscientists manipulate experimental stimuli while recording participant brain activity. They can then use encoding models to find out which brain "zone" (e.g. which region of interest,…
Background: Studies have shown the potential adverse health effects, ranging from headaches to cardiovascular disease, associated with long-term negative emotions and chronic stress. Since many indicators of stress are imperceptible to…
Social and affective relations may shape empathy to others' affective states. Previous studies also revealed that people tend to form very different mental representations of stimuli on the basis of their physical distance. In this regard,…
Animals learn to predict external contingencies from experience through a process of conditioning. A natural mechanism for conditioning is stimulus substitution, whereby the neuronal response to a stimulus with no prior behavioral…
Many tasks require flexibly modifying perception and behavior based on current goals. Humans can retrieve episodic memories from days to years ago, using them to contextualize and generalize behaviors across novel but structurally related…
Pain is an inherent part of human existence, manifesting as both physical and emotional experiences, and can be categorized as either acute or chronic. Over the years, extensive research has been conducted to understand the causes of pain…