相关论文: First in-vivo human magnetic particle imaging

We show that a single atomic magnetometer in a magnetically unshielded environment can be used to perform magnetic particle spectroscopy (MPS) and AC susceptometry (ACS) on liquid-suspended magnetic nanoparticles. We demonstrate methods…

Various imaging modalities allow for time-dependent image reconstructions from measurements where its acquisition also has a time-dependent nature. Magnetic particle imaging (MPI) falls into this class of imaging modalities and it thus also…

In recent years, sensors based on hot atomic vapor cells have emerged as a compact and highly sensitive means of measuring magnetic fields. Such sensors have been deployed in the field for the measurement of, e.g. biological systems,…

We demonstrate a new computational illumination technique that achieves large space-bandwidth-time product, for quantitative phase imaging of unstained live samples in vitro. Microscope lenses can have either large field of view (FOV) or…

Oblique plane microscopy (OPM) enables high speed, volumetric fluorescence imaging through a single-objective geometry. While these advantages have positioned OPM as a valuable tool to probe biological questions in animal models, its…

Microscopy enables detailed visualization and understanding of minute structures or processes. While cameras have significantly advanced optical, infrared, and electron microscopy, imaging nuclear magnetic resonance (NMR) signals on a…

The magnetorotational instability (MRI) is a crucial mechanism of angular momentum transport in a variety of astrophysical accretion disks. In systems accreting at well below the Eddington rate, such as the central black hole in the Milky…

We demonstrate an experimental method for direct 2D and 3D imaging of magnetic radio-frequency (rf) field distribution in metal-dielectric structures based on traveling wave (TW) magnetic resonance imaging (MRI) at ultra-high field (> 7T).…

A "heart attack" or myocardial infarction (MI), occurs when an artery supplying blood to the heart is abruptly occluded. The "gold standard" method for imaging MI is Cardiovascular Magnetic Resonance Imaging (MRI), with intravenously…

Currently, connectomes (e.g., functional or structural brain graphs) can be estimated in humans at $\approx 1~mm^3$ scale using a combination of diffusion weighted magnetic resonance imaging, functional magnetic resonance imaging and…

Magnetic particle imaging (MPI) offers exceptional contrast for magnetic nanoparticles (MNP) at high spatio-temporal resolution. A common procedure in MPI starts with a calibration scan to measure the system matrix (SM), which is then used…

Delivering sub-micrometer particles to an intense x-ray focus is a crucial aspect of single-particle diffractive-imaging experiments at x-ray free-electron lasers. Enabling direct visualization of sub-micrometer aerosol particle streams…

Magnetic Resonance Imaging (MRI) is the primary imaging modality used in the diagnosis, assessment, and treatment planning for brain pathologies. However, most automated MRI analysis tools, such as segmentation and registration pipelines,…

Single-photon emission computed tomography for myocardial perfusion imaging (MPI SPECT) is a widely used diagnostic tool for coronary artery disease. However, the procedure requires considerable scanning time, leading to patient discomfort…

Optical pumping of He-3 produces large (hyper) nuclear-spin polarizations independent of the magnetic resonance imaging (MRI) field strength. This allows lung MRI to be performed at reduced fields with many associated benefits, such as…

SPECT systems using pinhole apertures permit radiolabeled molecular distributions to be imaged in vivo in small animals. Nevertheless studying cardiovascular diseases by means of small animal models is very challenging. Specifically,…

Magnetic Resonance Imaging (MRI) is a well-established modality for pre-operative planning and is also explored for intra-operative guidance of procedures such as intravascular interventions. Among the experimental robot-assisted…

Magnetic resonance imaging (MRI) is a widely used biomedical imaging modality that derives much of its contrast from microscale magnetic field gradients in biological tissues. However, the connection between these sub-voxel field patterns…

Magnetic Particle Imaging (MPI) is an emerging imaging modality based on the magnetic response of superparamagnetic iron oxide nanoparticles to achieve high-resolution and real-time imaging without harmful radiation. One key challenge in…

A mathematical model is presented for predicting magnetic targeting of multifunctional carrier particles that are designed to deliver therapeutic agents to malignant tissue in vivo. These particles consist of a nonmagnetic core material…