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One of the hallmarks of Alzheimer's disease (AD) is the accumulation and spread of toxic aggregates of tau protein. The progression of AD tau pathology is thought to be highly stereotyped, which is in part due to the fact that tau can…

偏微分方程分析 · 数学 2024-01-09 Veronica Tora , Justin Torok , Michiel Bertsch , Ashish Raj

This work introduces a neural operator based surrogate modeling framework for neutron transport computation. Two architectures, the Deep Operator Network (DeepONet) and the Fourier Neural Operator (FNO), were trained for fixed source…

计算物理 · 物理学 2026-02-19 Md Hossain Sahadath , Qiyun Cheng , Shaowu Pan , Wei Ji

Neural Operators (NOs) are machine learning models designed to solve partial differential equations (PDEs) by learning to map between function spaces. Neural Operators such as the Deep Operator Network (DeepONet) and the Fourier Neural…

机器学习 · 计算机科学 2025-04-30 W. Diab , M. Al-Kobaisi

Continuum robots enable dexterous manipulation in constrained environments, but require accurate and efficient models for real-time manipulation and control. Traditional physics-based models can be computationally expensive and may suffer…

机器人学 · 计算机科学 2026-05-20 Branden Frieden , James M. Ferguson , Alan Kuntz , Varun Shankar

Neural Operators (NOs) are a powerful deep learning framework designed to learn the solution operator that arise from partial differential equations. This study investigates NOs ability to capture the stiff spatio-temporal dynamics of the…

机器学习 · 计算机科学 2026-03-19 Luca Pellegrini

Background: Traumatic brain injury modeling requires integrating volumetric neuroimaging, demographic parameters, and acquisition metadata. Finite element solvers are too computationally expensive for clinical settings. Neural operators…

机器学习 · 计算机科学 2026-04-27 Anusha Agarwal , Dibakar Roy Sarkar , Somdatta Goswami

Computationally efficient surrogates for parametrized physical models play a crucial role in science and engineering. Operator learning provides data-driven surrogates that map between function spaces. However, instead of full-field…

机器学习 · 计算机科学 2024-12-31 Daniel Zhengyu Huang , Nicholas H. Nelsen , Margaret Trautner

Neural operators, which aim to approximate mappings between infinite-dimensional function spaces, have been widely applied in the simulation and prediction of physical systems. However, the limited representational capacity of network…

机器学习 · 计算机科学 2025-06-03 Jin Song , Kenji Kawaguchi , Zhenya Yan

Neural operators aim to approximate the solution operator of a system of differential equations purely from data. They have shown immense success in modeling complex dynamical systems across various domains. However, the occurrence of…

机器学习 · 计算机科学 2025-04-01 Christopher Bülte , Philipp Scholl , Gitta Kutyniok

We present a graph neural network (GNN) based surrogate framework for molecular dynamics simulations that directly predicts atomic displacements and learns the underlying evolution operator of an atomistic system. Unlike conventional…

材料科学 · 物理学 2025-12-29 Judah Immanuel , Avik Mahata , Aniruddha Maiti

Alzheimer's disease involves progressive tau accumulation and spread, leading to regional brain atrophy and disruption of large-scale functional networks. While tau propagation and tissue degeneration have been widely modeled, how atrophy…

We propose a mathematical model for the onset and progression of Alzheimer's disease based on transport and diffusion equations. We treat brain neurons as a continuous medium and structure them by their degree of malfunctioning. Three…

生物物理 · 物理学 2020-12-29 Michiel Bertsch , Bruno Franchi , Valentina Meschini , Maria Carla Tesi , Andrea Tosin

Alzheimer's disease is the most common neurodegenerative disorder. Its pathological development is connected with the misfolding and accumulation of two toxic proteins: amyloid-beta and tau proteins. Mathematical models provide a valuable…

数值分析 · 数学 2026-04-21 Beatrice Caon , Mattia Corti , Francesca Bonizzoni , Paola F. Antonietti

We construct efficient surrogate models for parametric forward operators arising in brain tumor growth simulations, governed by coupled semilinear parabolic reaction-diffusion systems on heterogeneous two- and three-dimensional domains. We…

数值分析 · 数学 2026-03-17 Asikul Islam , Md Rezwan Bin Mizan , Maxim Olshanskii , Andreas Mang

Alzheimer's disease is characterised by the spreading of misfolded proteins and progressive structural changes in the brain. Despite significant clinical research, understanding how microscopic protein dynamics translate into macroscopic…

计算工程、金融与科学 · 计算机科学 2026-03-23 A. Vazquez-Palomo , C. Betegón , J. Weickenmeier , E. Martínez-Pañeda

We integrate neural operators with diffusion models to address the spectral limitations of neural operators in surrogate modeling of turbulent flows. While neural operators offer computational efficiency, they exhibit deficiencies in…

机器学习 · 计算机科学 2025-02-14 Vivek Oommen , Aniruddha Bora , Zhen Zhang , George Em Karniadakis

Trajectory planning is a fundamental problem in robotics. It facilitates a wide range of applications in navigation and motion planning, control, and multi-agent coordination. Trajectory planning is a difficult problem due to its…

机器人学 · 计算机科学 2024-02-13 Zihan Yu , Yuqing Tang

Neural operators have emerged as powerful surrogates for dynamical systems due to their grid-invariant properties and computational efficiency. However, the Fourier-based neural operator framework inherently truncates high-frequency…

机器学习 · 计算机科学 2026-04-09 Tianyue Yang , Xiao Xue

Event-Based Models (EBMs) infer biomarker progression from cross-sectional data but typically only as ordinal sequences and rely on rigid model assumptions. We propose \textsc{Tempo}, a Transformer architecture that learns both ordinal and…

机器学习 · 计算机科学 2026-04-28 Hongtao Hao , Joseph L. Austerweil

Topic models have been widely used to learn text representations and gain insight into document corpora. To perform topic discovery, most existing neural models either take document bag-of-words (BoW) or sequence of tokens as input followed…

计算与语言 · 计算机科学 2021-07-12 Madhur Panwar , Shashank Shailabh , Milan Aggarwal , Balaji Krishnamurthy
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