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Objective. As proton arc therapy (PAT) approaches clinical implementation, optimizing treatment plans for this innovative delivery modality remains challenging, especially in addressing arc delivery time. Existing algorithms for minimizing…

医学物理 · 物理学 2024-10-11 S. Wuyckens , G. Janssens , M. Chocan Vera , J. Sundstrom , D. Di Perri , E. Sterpin , K. Souris , J. A. Lee

Today, intensity-modulated radiation therapy (IMRT) is one of the methods used to treat brain tumors. In conventional treatment planning methods, after identifying planning target volume (PTV), and organs at risk (OARs), and determining the…

定量方法 · 定量生物学 2023-05-15 Mobina Naeemi , Mohamad Reza Esmaeili , Iraj Abedi

Radiotherapy inverse planning often requires planners to modify parameters in the treatment planning system's objective function to produce clinically acceptable plans. Due to the manual steps in this process, plan quality can vary…

医学物理 · 物理学 2022-05-11 Kelsey Maass , Aleksandr Aravkin , Minsun Kim

Whole-brain radiotherapy (WBRT) is a common treatment due to its simplicity and effectiveness. While automated Field-in-Field (Auto-FiF) functions assist WBRT planning in modern treatment planning systems, it still requires manual…

医学物理 · 物理学 2026-01-05 Adnan Jafar , An Qin , Gavin Atkins , Xiaoyu Hu , Yin Gao , Xun Jia

Stereotactic body radiotherapy (SBRT) is characterized by delivering a high amount of dose in a short period of time. In SBRT the dose is delivered using open fields (e.g., beam's-eye-view) known as "apertures". Mathematical methods can be…

医学物理 · 物理学 2015-06-15 Hamed Yarmand , David Craft

Online adaptive radiation therapy (ART) has great promise to significantly reduce normal tissue toxicity and/or improve tumor control through real-time treatment adaptations based on the current patient anatomy. However, the major technical…

医学物理 · 物理学 2015-05-18 Chunhua Men , Xun Jia , Steve. B. Jiang

Objective: Machine learning (ML) based radiation treatment (RT) planning addresses the iterative and time-consuming nature of conventional inverse planning. Given the rising importance of Magnetic resonance (MR) only treatment planning…

医学物理 · 物理学 2022-06-13 Aly Khalifa , Jeff Winter , Inmaculada Navarro , Chris McIntosh , Thomas G. Purdie

Online adaptive radiation therapy (ART) is an attractive concept that promises the ability to deliver an optimal treatment in response to the inter-fraction variability in patient anatomy. However, it has yet to be realized due to technical…

医学物理 · 物理学 2015-05-14 Xuejun Gu , Dongju Choi , Chunhua Men , Hubert Pan , Amitava Majumdar , Steve B. Jiang

Traditionally, optimization of radiation therapy (RT) treatment plans has been done before the initiation of RT course, using population-wide estimates for patients' response to therapy. However, recent technological advancements have…

医学物理 · 物理学 2021-02-15 Stefan C. M. ten Eikelder , Ali Ajdari , Thomas Bortfeld , Dick den Hertog

Using inverse planning tools to create radiotherapy treatment plans is an iterative process, where clinical trade-offs are explored by changing the relative importance of different objectives and rerunning the optimizer until a desirable…

Radiation therapy is the mainstay treatment for cervical cancer, and its ultimate goal is to ensure the planning target volume (PTV) reaches the prescribed dose while reducing dose deposition of organs-at-risk (OARs) as much as possible. To…

计算机视觉与模式识别 · 计算机科学 2024-08-27 Lu Wen , Wenxia Yin , Zhenghao Feng , Xi Wu , Deng Xiong , Yan Wang

Head-and-neck cancer (HNC) planning is difficult because multiple critical organs-at-risk (OARs) are close to complex targets. Intensity-modulated carbon-ion therapy (IMCT) offers superior dose conformity and OAR sparing but remains slow…

The aim is to evaluate whether smart worklist prioritization by artificial intelligence (AI) can optimize the radiology workflow and reduce report turnaround times (RTAT) for critical findings in chest radiographs (CXRs). Furthermore, we…

We highlight emerging uses of artificial intelligence (AI) in the field of theranostics, focusing on its significant potential to enable routine and reliable personalization of radiopharmaceutical therapies (RPTs). Personalized RPTs require…

With the advancement of treatment modalities in radiation therapy for cancer patients, outcomes have improved, but at the cost of increased treatment plan complexity and planning time. The accurate prediction of dose distributions would…

医学物理 · 物理学 2018-12-03 Dan Nguyen , Troy Long , Xun Jia , Weiguo Lu , Xuejun Gu , Zohaib Iqbal , Steve Jiang

Radiologists face increasing workload pressures amid growing imaging volumes, creating risks of burnout and delayed reporting times. While artificial intelligence (AI) based automated radiology report generation shows promise for reporting…

Pancreas stereotactic body radiotherapy treatment planning requires planners to make sequential, time consuming interactions with the treatment planning system (TPS) to reach the optimal dose distribution. We seek to develop a reinforcement…

We propose Artificial Intelligence Prospective Randomized Observer Blinding Evaluation (AI-PROBE) for quantitative clinical performance evaluation of radiology AI systems within prospective randomized clinical trials. AI-PROBE encompasses a…

医学物理 · 物理学 2020-03-02 Axel Wismüller , Larry Stockmaster

Objective: Radiation therapy treatment planning is a time-consuming process involving iterative adjustments of hyperparameters. To automate the treatment planning process, we propose a meta-optimization framework, called MetaPlanner (MP).…

医学物理 · 物理学 2022-02-22 Charles Huang , Yusuke Nomura , Yong Yang , Lei Xing

Radiation therapy (RT) is a medical treatment to kill cancer cells or shrink tumors. To manually schedule patients for RT is a time-consuming and challenging task. By the use of optimization, patient schedules for RT can be created…

最优化与控制 · 数学 2023-05-04 Sara Frimodig , Per Enqvist , Mats Carlsson , Carole Mercier