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Biomedical ontology refers to a shared conceptualization for a biomedical domain of interest that has vastly improved data management and data sharing through the open data movement. The rapid growth and availability of biomedical data make…

数据库 · 计算机科学 2018-02-13 Feichen Shen , Yugyung Lee

LLMs have demonstrated impressive performance in answering medical questions, such as achieving passing scores on medical licensing examinations. However, medical board exams or general clinical questions do not capture the complexity of…

计算与语言 · 计算机科学 2026-02-19 Hanjie Chen , Zhouxiang Fang , Yash Singla , Mark Dredze

Rule-based reasoning over natural language input arises in domains where decisions must be auditable and justifiable: clinical protocols specify eligibility criteria in prose, evidence rules define admissibility through textual conditions,…

人工智能 · 计算机科学 2026-01-06 Albert Sadowski , Jarosław A. Chudziak

LIME is a popular approach for explaining a black-box prediction through an interpretable model that is trained on instances in the vicinity of the predicted instance. To generate these instances, LIME randomly selects a subset of the…

机器学习 · 统计学 2019-11-01 Amir Hossein Akhavan Rahnama , Henrik Boström

Concept Bottleneck Models (CBMs) offer interpretable alternatives to black-box predictors by introducing human-relatable concepts before the final output. However, existing CBMs struggle to verify whether predicted concepts correspond to…

机器学习 · 计算机科学 2026-05-15 Yingying Fang , Haijie Xu , Shuang Wu , Mariathasan Anish , Guang Yang

Large language models (LLMs) face significant challenges in specialized biomedical tasks due to the inherent complexity of medical reasoning and the sensitive nature of clinical data. Existing LLMs often struggle with intricate medical…

计算与语言 · 计算机科学 2026-05-12 Zongxian Yang , Jiayu Qian , Kay Chen Tan , Hau-San Wong , Yulong Chen , Haoyu Zhang , Zhi-An Huang

The need for reliable model explanations is prominent for many machine learning applications, particularly for tabular and time-series data as their use cases often involve high-stakes decision making. Towards this goal, we introduce a…

机器学习 · 计算机科学 2023-05-29 Aya Abdelsalam Ismail , Sercan Ö. Arik , Jinsung Yoon , Ankur Taly , Soheil Feizi , Tomas Pfister

We introduce CEMTM, a context-enhanced multimodal topic model designed to infer coherent and interpretable topic structures from both short and long documents containing text and images. CEMTM builds on fine-tuned large vision language…

计算与语言 · 计算机科学 2025-10-07 Amirhossein Abaskohi , Raymond Li , Chuyuan Li , Shafiq Joty , Giuseppe Carenini

Current methods for embedding-based query answering over incomplete Knowledge Graphs (KGs) only focus on inductive reasoning, i.e., predicting answers by learning patterns from the data, and lack the complementary ability to do deductive…

人工智能 · 计算机科学 2023-09-01 Medina Andresel , Trung-Kien Tran , Csaba Domokos , Pasquale Minervini , Daria Stepanova

This work presents an ontology-integrated large language model (LLM) framework for chemical engineering that unites structured domain knowledge with generative reasoning. The proposed pipeline aligns model training and inference with the…

机器学习 · 计算机科学 2025-12-15 Crystal Su , Kuai Yu , Jingrui Zhang , Mingyuan Shao , Daniel Bauer

We introduce a novel contextual embedding model med-gte-hybrid that was derived from the gte-large sentence transformer to extract information from unstructured clinical narratives. Our model tuning strategy for med-gte-hybrid combines…

计算与语言 · 计算机科学 2025-12-02 Aditya Kumar , Simon Rauch , Mario Cypko , Oliver Amft

Question answering is a natural language understanding task that involves reasoning over both explicit context, and unstated relevant domain knowledge. Despite the high cost of training, large language models (LLMs) -- the backbone of most…

计算与语言 · 计算机科学 2025-04-24 Laura Cabello , Carmen Martin-Turrero , Uchenna Akujuobi , Anders Søgaard , Carlos Bobed

Universal multimodal embedding (UME) maps heterogeneous inputs into a shared retrieval space with a single model. Recent approaches improve UME by generating explicit chain-of-thought (CoT) rationales before extracting embeddings, enabling…

计算机视觉与模式识别 · 计算机科学 2026-04-21 Chenwei He , Xiangzhao Hao , Tianyu Yang , Yuxiang Ma , Yuheng Jia , Lingxiang Wu , Chaoyang Zhao , Haiyun Guo , Jinqiao Wang

Automatic Question Answering (QA) has been successfully applied in various domains such as search engines and chatbots. Biomedical QA (BQA), as an emerging QA task, enables innovative applications to effectively perceive, access and…

计算与语言 · 计算机科学 2024-01-17 Qiao Jin , Zheng Yuan , Guangzhi Xiong , Qianlan Yu , Huaiyuan Ying , Chuanqi Tan , Mosha Chen , Songfang Huang , Xiaozhong Liu , Sheng Yu

Accurate uncertainty quantification is a critical challenge in machine learning. While neural networks are highly versatile and capable of learning complex patterns, they often lack interpretability due to their ``black box'' nature. On the…

机器学习 · 计算机科学 2025-11-18 Pragatheeswaran Vipulananthan , Kamal Premaratne , Dilip Sarkar , Manohar N. Murthi

Simulating quantum imaginary-time evolution (QITE) is a major promise of quantum computation. However, the known algorithms are either probabilistic (repeat until success) with impractically small success probabilities or coherent (quantum…

量子物理 · 物理学 2023-11-02 Thais de Lima Silva , Márcio M. Taddei , Stefano Carrazza , Leandro Aolita

Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the…

计算机视觉与模式识别 · 计算机科学 2025-05-13 Chao Ding , Mouxiao Bian , Pengcheng Chen , Hongliang Zhang , Tianbin Li , Lihao Liu , Jiayuan Chen , Zhuoran Li , Yabei Zhong , Yongqi Liu , Haiqing Huang , Dongming Shan , Junjun He , Jie Xu

Although explainability is essential in the clinical diagnosis, most deep learning models still function as black boxes without elucidating their decision-making process. In this study, we investigate the explainable model development that…

计算机视觉与模式识别 · 计算机科学 2024-09-20 Yunhe Gao , Difei Gu , Mu Zhou , Dimitris Metaxas

Unsupervised methods are widely used to induce latent semantic structure from large text collections, yet their outputs often contain incoherent, redundant, or poorly grounded clusters that are difficult to validate without labeled data. We…

计算与语言 · 计算机科学 2026-04-21 Tunazzina Islam

The amount of publicly available biomedical literature has been growing rapidly in recent years, yet question answering systems still struggle to exploit the full potential of this source of data. In a preliminary processing step, many…

信息检索 · 计算机科学 2018-01-10 Ferenc Galkó , Carsten Eickhoff