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Alzheimer's disease progression prediction is critical for patients with early Mild Cognitive Impairment (MCI) to enable timely intervention and improve their quality of life. While existing progression prediction techniques demonstrate…

计算机视觉与模式识别 · 计算机科学 2025-11-18 Zhongying Deng , Shujun Wang , Angelica I Aviles-Rivero , Zoe Kourtzi , Carola-Bibiane Schönlieb

Alzheimer's disease is a progressive neurological disorder characterized by cognitive impairment and memory loss. With the increasing aging population, the incidence of AD is continuously rising, making early diagnosis and intervention an…

图像与视频处理 · 电气工程与系统科学 2023-11-23 Guian Fang , Mengsha Liu , Yi Zhong , Zhuolin Zhang , Jiehui Huang , Zhenchao Tang , Calvin Yu-Chian Chen

This paper is a submission to the Alzheimer's Dementia Recognition through Spontaneous Speech (ADReSS) challenge, which aims to develop methods that can assist in the automated prediction of severity of Alzheimer's Disease from speech data.…

机器学习 · 计算机科学 2021-06-18 Morteza Rohanian , Julian Hough , Matthew Purver

An interpretable machine learning (ML) framework is introduced to enhance the diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) by ensuring robustness of the ML models' interpretations. The dataset used comprises…

Alzheimer's disease (AD) progresses heterogeneously across individuals, motivating subject-specific synthesis of follow-up magnetic resonance imaging (MRI) to support progression assessment. While Diffusion Transformers (DiT), an emerging…

计算机视觉与模式识别 · 计算机科学 2026-04-16 Juneyong Lee , Geonwoo Baek , Ikbeom Jang

Background: The increasing availability of databases containing both magnetic resonance imaging (MRI) and genetic data allows researchers to utilize multimodal data to better understand the characteristics of dementia of Alzheimer's type…

Transfer learning represents a recent paradigm shift in the way we build artificial intelligence (AI) systems. In contrast to training task-specific models, transfer learning involves pre-training deep learning models on a large corpus of…

Alzheimer's disease (AD) constitutes a complex neurocognitive disease and is the main cause of dementia. Although many studies have been proposed targeting at diagnosing dementia through spontaneous speech, there are still limitations.…

计算与语言 · 计算机科学 2023-08-24 Loukas Ilias , Dimitris Askounis

Alzheimer's disease (AD) constitutes a neurodegenerative disease with serious consequences to peoples' everyday lives, if it is not diagnosed early since there is no available cure. Alzheimer's is the most common cause of dementia, which…

计算与语言 · 计算机科学 2023-01-18 Loukas Ilias , Dimitris Askounis , John Psarras

Early diagnosis of Alzheimer's disease (AD) is critical for intervention before irreversible neurodegeneration occurs. Structural MRI (sMRI) is widely used for AD diagnosis, but conventional deep learning approaches primarily rely on…

图像与视频处理 · 电气工程与系统科学 2025-03-04 Shijia Zhang , Xiyu Ding , Brian Caffo , Junyu Chen , Cindy Zhang , Hadi Kharrazi , Zheyu Wang

Magnetic Resonance Imaging (MRI) provides detailed structural information, while functional MRI (fMRI) captures temporal brain activity. In this work, we present a multimodal deep learning framework that integrates MRI and fMRI for…

计算机视觉与模式识别 · 计算机科学 2026-03-17 Anima Kujur , Zahra Monfared

Timely and accurate diagnosis of neurodegenerative disorders, such as Alzheimer's disease, is central to disease management. Existing deep learning models require large-scale annotated datasets and often function as "black boxes".…

计算机视觉与模式识别 · 计算机科学 2025-04-15 Duy-Cat Can , Quang-Huy Tang , Huong Ha , Binh T. Nguyen , Oliver Y. Chén

Detection of Alzheimer's Disease (AD) from neuroimaging data such as MRI through machine learning have been a subject of intense research in recent years. Recent success of deep learning in computer vision have progressed such research…

计算机视觉与模式识别 · 计算机科学 2017-12-01 Marcia Hon , Naimul Khan

Deep learning has become an important tool for Alzheimer's disease (AD) classification from structural MRI. Many existing studies analyze individual 2D slices extracted from MRI volumes, while clinical neuroimaging practice typically relies…

计算机视觉与模式识别 · 计算机科学 2026-03-19 Md Sifat , Sania Akter , Akif Islam , Md. Ekramul Hamid , Abu Saleh Musa Miah , Najmul Hassan , Md Abdur Rahim , Jungpil Shin

Unveiling pathological brain changes associated with Alzheimer's disease (AD) is a challenging task especially that people do not show symptoms of dementia until it is late. Over the past years, neuroimaging techniques paved the way for…

定量方法 · 定量生物学 2018-08-07 Mayssa Soussia , Islem Rekik

Alzheimer's disease (AD) is a progressive neurodegenerative disorder in which pathological changes begin many years before the onset of clinical symptoms, making early detection essential for timely intervention. T1-weighted (T1w) Magnetic…

计算机视觉与模式识别 · 计算机科学 2026-01-21 Jason Qiu

This paper explores deterioration in Alzheimers Disease using Machine Learning. Subjects were split into two datasets based on baseline diagnosis (Cognitively Normal, Mild Cognitive Impairment), with outcome of deterioration at final visit…

机器学习 · 计算机科学 2023-06-21 Henry Musto , Daniel Stamate , Ida Pu , Daniel Stahl

FDG-PET reveals altered brain metabolism in individuals with mild cognitive impairment (MCI) and Alzheimer's disease (AD). Some biomarkers derived from FDG-PET by computer-aided-diagnosis (CAD) technologies have been proved that they can…

图像与视频处理 · 电气工程与系统科学 2021-11-10 Wenju Cui , Caiying Yan , Zhuangzhi Yan , Yunsong Peng , Yilin Leng , Chenlu Liu , Shuangqing Chen , Xi Jiang

The ability to accurately detect onset of dementia is important in the treatment of the disease. Clinically, the diagnosis of Alzheimer Disease (AD) and Mild Cognitive Impairment (MCI) patients are based on an integrated assessment of…

信号处理 · 电气工程与系统科学 2022-11-18 Wan-Ting Hsieh , Jeremy Lefort-Besnard , Hao-Chun Yang , Li-Wei Kuo , Chi-Chun Lee

In the realm of audio-language pre-training (ALP), the challenge of achieving cross-modal alignment is significant. Moreover, the integration of audio inputs with diverse distributions and task variations poses challenges in developing…

声音 · 计算机科学 2024-06-13 Hang Zhao , Yifei Xin , Zhesong Yu , Bilei Zhu , Lu Lu , Zejun Ma