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Generative pre-trained transformer (GPT) models have shown promise in clinical entity and relation extraction tasks because of their precise extraction and contextual understanding capability. In this work, we further leverage the Unified…

计算与语言 · 计算机科学 2024-07-16 Kriti Bhattarai , Inez Y. Oh , Zachary B. Abrams , Albert M. Lai

Objective: Our study aimed to construct an exhaustive Complementary and Integrative Health (CIH) Lexicon (CIHLex) to better represent the often underrepresented physical and psychological CIH approaches in standard terminologies. We also…

计算与语言 · 计算机科学 2023-11-15 Huixue Zhou , Robin Austin , Sheng-Chieh Lu , Greg Silverman , Yuqi Zhou , Halil Kilicoglu , Hua Xu , Rui Zhang

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

计算与语言 · 计算机科学 2025-07-10 Garapati Keerthana , Manik Gupta

The injection of domain-specific knowledge is crucial for adapting language models (LMs) to specialized fields such as biomedicine. While most current approaches rely on unstructured text corpora, this study explores two complementary…

计算与语言 · 计算机科学 2026-04-21 Jaafer Klila , Sondes Bannour Souihi , Rahma Boujelben , Nasredine Semmar , Lamia Hadrich Belguith

Clinical decision-making requires synthesizing heterogeneous evidence, including patient histories, clinical guidelines, and trajectories of comparable cases. While large language models (LLMs) offer strong reasoning capabilities, they…

人工智能 · 计算机科学 2026-03-03 Shuheng Chen , Namratha Patil , Haonan Pan , Angel Hsing-Chi Hwang , Yao Du , Ruishan Liu , Jieyu Zhao

We used MetaMap and YTEX as a basis for the construc- tion of two separate systems to participate in the 2013 ShARe/CLEF eHealth Task 1[9], the recognition of clinical concepts. No modifications were directly made to these systems, but…

信息检索 · 计算机科学 2014-02-10 John David Osborne , Binod Gyawali , Thamar Solorio

Clinicians are increasingly looking towards machine learning to gain insights about patient evolutions. We propose a novel approach named Multi-Modal UMLS Graph Learning (MMUGL) for learning meaningful representations of medical concepts…

机器学习 · 计算机科学 2024-02-07 Manuel Burger , Gunnar Rätsch , Rita Kuznetsova

Electronic health records (EHR) contain large volumes of unstructured text, requiring the application of Information Extraction (IE) technologies to enable clinical analysis. We present the open-source Medical Concept Annotation Toolkit…

Background: Widespread adoption of electronic health records (EHRs) has enabled secondary use of EHR data for clinical research and healthcare delivery. Natural language processing (NLP) techniques have shown promise in their capability to…

信息检索 · 计算机科学 2021-06-15 Sijia Liu , Yanshan Wang , Andrew Wen , Liwei Wang , Na Hong , Feichen Shen , Steven Bedrick , William Hersh , Hongfang Liu

Intensive Care Units (ICU) require comprehensive patient data integration for enhanced clinical outcome predictions, crucial for assessing patient conditions. Recent deep learning advances have utilized patient time series data, and fusion…

机器学习 · 计算机科学 2023-11-14 Samyak Jain , Manuel Burger , Gunnar Rätsch , Rita Kuznetsova

Automated knowledge curation for biomedical ontologies is key to ensure that they remain comprehensive, high-quality and up-to-date. In the era of foundational language models, this study compares and analyzes three NLP paradigms for…

机器学习 · 计算机科学 2023-12-21 Emily Groves , Minhong Wang , Yusuf Abdulle , Holger Kunz , Jason Hoelscher-Obermaier , Ronin Wu , Honghan Wu

We introduce a novel graph-based Retrieval-Augmented Generation (RAG) framework specifically designed for the medical domain, called \textbf{MedGraphRAG}, aimed at enhancing Large Language Model (LLM) capabilities for generating…

计算机视觉与模式识别 · 计算机科学 2024-10-17 Junde Wu , Jiayuan Zhu , Yunli Qi , Jingkun Chen , Min Xu , Filippo Menolascina , Vicente Grau

Despite the remarkable progress of Large Language Models (LLMs), their performance in question answering (QA) remains limited by the lack of domain-specific and up-to-date knowledge. Retrieval-Augmented Generation (RAG) addresses this…

信息检索 · 计算机科学 2025-09-17 Yaodong Su , Yixiang Fang , Yingli Zhou , Quanqing Xu , Chuanhui Yang

Contextual word embedding models, such as BioBERT and Bio_ClinicalBERT, have achieved state-of-the-art results in biomedical natural language processing tasks by focusing their pre-training process on domain-specific corpora. However, such…

计算与语言 · 计算机科学 2021-06-04 George Michalopoulos , Yuanxin Wang , Hussam Kaka , Helen Chen , Alexander Wong

Query Processing (QP) is optimized by a Cloud-based cache by storing the frequently accessed data closer to users. Nevertheless, the lack of focus on user intention type in queries affected the efficiency of QP in prevailing works. Thus, by…

机器学习 · 计算机科学 2024-06-10 Sakshi Mahendru

Machine Unlearning (MU) has recently attracted considerable attention as a solution to privacy and copyright issues in large language models (LLMs). Existing MU methods aim to remove specific target sentences from an LLM while minimizing…

计算与语言 · 计算机科学 2025-09-22 Tomoya Yamashita , Yuuki Yamanaka , Masanori Yamada , Takayuki Miura , Toshiki Shibahara , Tomoharu Iwata

Automated annotation of clinical text with standardized medical concepts is critical for enabling structured data extraction and decision support. SNOMED CT provides a rich ontology for labeling clinical entities, but manual annotation is…

计算与语言 · 计算机科学 2025-08-05 Ali Noori , Pratik Devkota , Somya Mohanty , Prashanti Manda

Large language models (LLMs) offer new opportunities for constructing knowledge graphs (KGs) from unstructured clinical narratives. However, existing approaches often rely on structured inputs and lack robust validation of factual accuracy…

人工智能 · 计算机科学 2026-01-06 Udiptaman Das , Krishnasai B. Atmakuri , Duy Ho , Chi Lee , Yugyung Lee

Effective data-driven biomedical discovery requires data curation: a time-consuming process of finding, organizing, distilling, integrating, interpreting, annotating, and validating diverse information into a structured form suitable for…

The effectiveness of artificial intelligence (AI) in healthcare is significantly hindered by unstructured clinical documentation, which results in noisy, inconsistent, and logically fragmented training data. To address this challenge, we…

机器学习 · 计算机科学 2025-10-21 Dun Liu , Qin Pang , Guangai Liu , Hongyu Mou , Jipeng Fan , Yiming Miao , Pin-Han Ho , Limei Peng
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