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Multimodal pathology-genomic analysis has become increasingly prominent in cancer survival prediction. However, existing studies mainly utilize multi-instance learning to aggregate patch-level features, neglecting the information loss of…

计算机视觉与模式识别 · 计算机科学 2025-05-21 Mingcheng Qu , Guang Yang , Donglin Di , Tonghua Su , Yue Gao , Yang Song , Lei Fan

Multimodal representation learning is a challenging task in which previous work mostly focus on either uni-modality pre-training or cross-modality fusion. In fact, we regard modeling multimodal representation as building a skyscraper, where…

计算与语言 · 计算机科学 2024-08-15 Ronghao Lin , Haifeng Hu

Medical vision-and-language pre-training provides a feasible solution to extract effective vision-and-language representations from medical images and texts. However, few studies have been dedicated to this field to facilitate medical…

计算机视觉与模式识别 · 计算机科学 2022-09-16 Zhihong Chen , Yuhao Du , Jinpeng Hu , Yang Liu , Guanbin Li , Xiang Wan , Tsung-Hui Chang

Electronic Health Record (EHR) datasets from Intensive Care Units (ICU) contain a diverse set of data modalities. While prior works have successfully leveraged multiple modalities in supervised settings, we apply advanced self-supervised…

机器学习 · 计算机科学 2024-03-28 Fabian Baldenweg , Manuel Burger , Gunnar Rätsch , Rita Kuznetsova

Defining and separating cancer subtypes is essential for facilitating personalized therapy modality and prognosis of patients. The definition of subtypes has been constantly recalibrated as a result of our deepened understanding. During…

机器学习 · 计算机科学 2022-07-21 Zheng Chen , Ziwei Yang , Lingwei Zhu , Guang Shi , Kun Yue , Takashi Matsubara , Shigehiko Kanaya , MD Altaf-Ul-Amin

Multi-modal entity alignment aims to identify equivalent entities between two different multi-modal knowledge graphs, which consist of structural triples and images associated with entities. Most previous works focus on how to utilize and…

计算与语言 · 计算机科学 2022-09-05 Zhenxi Lin , Ziheng Zhang , Meng Wang , Yinghui Shi , Xian Wu , Yefeng Zheng

Understanding relationships across multiple imaging modalities is central to neuroimaging research. We introduce the Integrative Variational Autoencoder (InVA), the first hierarchical VAE framework for image-on-image regression in…

图像与视频处理 · 电气工程与系统科学 2025-09-15 Bowen Lei , Yeseul Jeon , Rajarshi Guhaniyogi , Aaron Scheffler , Bani Mallick , Alzheimer's Disease Neuroimaging Initiatives

Major pathological response (pR) following neoadjuvant therapy is a clinically meaningful endpoint in non-small cell lung cancer, strongly associated with improved survival. However, accurate preoperative prediction of pR remains…

An active challenge in developing multimodal machine learning (ML) models for healthcare is handling missing modalities during training and deployment. As clinical datasets are inherently temporal and sparse in terms of modality presence,…

机器学习 · 计算机科学 2026-05-08 Andrew Wang , Ellie Pavlick , Ritambhara Singh

Multiview clustering (MVC) segregates data samples into meaningful clusters by synthesizing information across multiple views. Moreover, deep learning-based methods have demonstrated their strong feature learning capabilities in MVC…

机器学习 · 计算机科学 2024-03-22 Hao Yang , Hua Mao , Wai Lok Woo , Jie Chen , Xi Peng

State-of-the-art high-spectral-efficiency communication systems employ high-order modulation formats coupled with high symbol rates to accommodate the ever-growing demand for data rate-hungry applications. However, such systems are more…

Aiming at exploiting the rich information in user behaviour sequences, sequential recommendation has been widely adopted in real-world recommender systems. However, current methods suffer from the following issues: 1) sparsity of user-item…

信息检索 · 计算机科学 2022-12-06 Yu Wang , Hengrui Zhang , Zhiwei Liu , Liangwei Yang , Philip S. Yu

Neuroimaging studies often involve the collection of multiple data modalities. These modalities contain both shared and mutually exclusive information about the brain. This work aims at finding a scalable and interpretable method to fuse…

机器学习 · 计算机科学 2021-05-05 Eloy Geenjaar , Noah Lewis , Zening Fu , Rohan Venkatdas , Sergey Plis , Vince Calhoun

A new maximum likelihood estimation approach for blind channel equalization, using variational autoencoders (VAEs), is introduced. Significant and consistent improvements in the error rate of the reconstructed symbols, compared to constant…

信号处理 · 电气工程与系统科学 2018-03-06 Avi Caciularu , David Burshtein

Biomedical imaging and RNA sequencing with single-cell resolution improves our understanding of white blood cell diseases like leukemia. By combining morphological and transcriptomic data, we can gain insights into cellular functions and…

计算机视觉与模式识别 · 计算机科学 2024-08-26 Gizem Mert , Ario Sadafi , Raheleh Salehi , Nassir Navab , Carsten Marr

Multimodal deep learning has shown strong potential in medical applications by integrating heterogeneous data sources such as medical images and structured clinical variables. However, most existing approaches implicitly assume complete…

机器学习 · 计算机科学 2026-05-13 Camillo Maria Caruso , Valerio Guarrasi , Paolo Soda

Building scalable models to learn from diverse, multimodal data remains an open challenge. For vision-language data, the dominant approaches are based on contrastive learning objectives that train a separate encoder for each modality. While…

计算机视觉与模式识别 · 计算机科学 2022-10-24 Xinyang Geng , Hao Liu , Lisa Lee , Dale Schuurmans , Sergey Levine , Pieter Abbeel

With the rapid advances in high-throughput sequencing technologies, the focus of survival analysis has shifted from examining clinical indicators to incorporating genomic profiles with pathological images. However, existing methods either…

图像与视频处理 · 电气工程与系统科学 2023-09-25 Fengtao Zhou , Hao Chen

Effective treatment for rectal cancer relies on accurate lymph node metastasis (LNM) staging. However, radiological criteria based on lymph node (LN) size, shape and texture morphology have limited diagnostic accuracy. In this work, we…

计算机视觉与模式识别 · 计算机科学 2025-07-17 Benjamin Keel , Aaron Quyn , David Jayne , Maryam Mohsin , Samuel D. Relton

Multimodal MRI offers complementary information for brain tumor segmentation, but clinical scans often lack one or more modalities, which degrades segmentation performance. In this paper, we propose UniME (Uni-Encoder Meets Multi-Encoders),…

计算机视觉与模式识别 · 计算机科学 2026-04-27 Peibo Song , Xiaotian Xue , Jinshuo Zhang , Zihao Wang , Jinhua Liu , Shujun Fu , Fangxun Bao , Si Yong Yeo