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Generalist pathology foundation models (PFMs), pretrained on large-scale multi-organ datasets, have demonstrated remarkable predictive capabilities across diverse clinical applications. However, their proficiency on the full spectrum of…

Explainable AI (XAI) in medical histopathology is essential for enhancing the interpretability and clinical trustworthiness of deep learning models in cancer diagnosis. However, the black-box nature of these models often limits their…

图像与视频处理 · 电气工程与系统科学 2025-05-06 Raktim Kumar Mondol , Ewan K. A. Millar , Peter H. Graham , Lois Browne , Arcot Sowmya , Erik Meijering

High dose-rate brachytherapy (HDRBT) is widely used for gynecological cancer treatment. Although commercial treatment planning systems (TPSs) have inverse optimization modules, it takes several iterations to adjust planning objectives to…

医学物理 · 物理学 2021-09-14 Huan Liu , Chang M Ma , Xun Jia , Chenyang Shen , Peter Klages , Kevin Albuquerque

Most commercially available treatment planning systems for brachytherapy operate based on physical dose and do not incorporate fractionation or tissue-specific response. The purpose of this study is to investigate the potential for…

医学物理 · 物理学 2017-12-04 Kaelyn Seeley , I-Chow J. Hsu , Tae Min Hong , J. Adam Cunha

We present Spectral GUI, a multiplatform breast MR image analysis tool designed to facilitate the segmentation of fibro glandular tissues and lesions in T1 weighted breast MR images via a graphical user interface (GUI). Spectral GUIR uses…

图像与视频处理 · 电气工程与系统科学 2020-04-21 Prajval Koul

German text, english abstract: Mortality in gynecologic cancers, including cervical, ovarian, vaginal and vulvar cancers, is more than 6% internationally [1]. In many countries external radiotherapy is supplemented by brachytherapy with…

医学物理 · 物理学 2018-03-13 Andre Mastmeyer

Recently, a new form of magnetic resonance imaging (MRI) called synthetic correlated diffusion (CDI$^s$) imaging was introduced and showed considerable promise for clinical decision support for cancers such as prostate cancer when compared…

图像与视频处理 · 电气工程与系统科学 2023-04-13 Chi-en Amy Tai , Hayden Gunraj , Alexander Wong

Gynecologic malignancies are a leading cause of death in women worldwide. Standard treatment for many primary and recurrent gynecologic cancer cases includes a combination of external beam radiation, followed by brachytherapy. Magnetic…

医学物理 · 物理学 2017-08-24 Tina Kapur , Jan Egger , Antonio Damato , Ehud J. Schmidt , Akila N. Viswanathan

The Multi-Objective Real-Valued Gene-pool Optimal Mixing Evolutionary Algorithm (MO-RV-GOMEA) has been proven effective and efficient in solving real-world problems. A prime example is optimizing treatment plans for prostate cancer…

Objective: Radiotherapy treatment planning is a time-consuming and potentially subjective process that requires the iterative adjustment of model parameters to balance multiple conflicting objectives. Recent advancements in frontier…

Around half of all cancer patients, world-wide, will receive some form of radiotherapy (RT) as part of their treatment. And yet, despite the rapid advance of high-throughput screening to identify successful chemotherapy drug candidates,…

医学物理 · 物理学 2023-04-07 Wojciech Ozimek , Rafał Banaś , Paweł Gora , Simon D. Angus , Monika J. Piotrowska

Gastric endoscopic screening is an effective way to decide appropriate gastric cancer (GC) treatment at an early stage, reducing GC-associated mortality rate. Although artificial intelligence (AI) has brought a great promise to assist…

图像与视频处理 · 电气工程与系统科学 2023-08-16 Yujin Oh , Go Eun Bae , Kyung-Hee Kim , Min-Kyung Yeo , Jong Chul Ye

In 2020, according to WHO, breast cancer affected 2.3 million women worldwide, resulting in 685,000 fatalities. By the end of the year, approximately 7.8 million women worldwide had survived their breast cancer making it the most widespread…

人机交互 · 计算机科学 2023-09-29 Niki Najafi , Miranda Addie , Sarkis Meterissian , Marta Kersten-Oertel

Cervical Cancer continues to be the leading gynecological malignancy, posing a persistent threat to women's health on a global scale. Early screening via cytology Whole Slide Image (WSI) diagnosis is critical to prevent this Cancer…

计算机视觉与模式识别 · 计算机科学 2024-07-30 Honglin Li , Yusuan Sun , Chenglu Zhu , Yunlong Zhang , Shichuan Zhang , Zhongyi Shui , Pingyi Chen , Jingxiong Li , Sunyi Zheng , Can Cui , Lin Yang

Medical image segmentation continues to advance rapidly, yet rigorous comparison between methods remains challenging due to a lack of standardized and customizable tooling. In this work, we present the current state of the Medical Imaging…

计算机视觉与模式识别 · 计算机科学 2025-07-29 Adrian Celaya , Tucker Netherton , Dawid Schellingerhout , Caroline Chung , Beatrice Riviere , David Fuentes

Detecting fraudulent transactions is an essential component to control risk in e-commerce marketplaces. Apart from rule-based and machine learning filters that are already deployed in production, we want to enable efficient real-time…

机器学习 · 计算机科学 2022-08-25 Mingxuan Lu , Zhichao Han , Susie Xi Rao , Zitao Zhang , Yang Zhao , Yinan Shan , Ramesh Raghunathan , Ce Zhang , Jiawei Jiang

Cancer treatments require personalized approaches based on a patient's clinical condition, medical history, and evidence-based guidelines. The National Comprehensive Cancer Network (NCCN) provides frequently updated, complex guidelines…

信息检索 · 计算机科学 2025-02-25 Abdul M. Mohammed , Iqtidar Mansoor , Sarah Blythe , Dennis Trujillo

Breast cancer is the most commonly diagnosed cancer and registers the highest number of deaths for women with cancer. Recent advancements in diagnostic activities combined with large-scale screening policies have significantly lowered the…

Pathology foundation models have shown strong retrospective performance, but whether such systems can support clinically relevant use remains unclear. This challenge is particularly important in breast cancer, where pathological assessment…

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