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Early and accurate detection of Alzheimer's disease (AD) remains a major challenge in medical diagnosis due to its subtle onset and progressive nature. This research introduces an explainable ensemble learning Framework designed to classify…

机器学习 · 计算机科学 2026-03-06 Nishan Mitra

Automatically detecting Alzheimer's Disease (AD) from spontaneous speech plays an important role in its early diagnosis. Recent approaches highly rely on the Transformer architectures due to its efficiency in modelling long-range context…

声音 · 计算机科学 2024-05-08 Zhongren Dong , Zixing Zhang , Weixiang Xu , Jing Han , Jianjun Ou , Björn W. Schuller

Speech datasets for identifying Alzheimer's disease (AD) are generally restricted to participants performing a single task, e.g. describing an image shown to them. As a result, models trained on linguistic features derived from such…

机器学习 · 计算机科学 2018-11-30 Aparna Balagopalan , Jekaterina Novikova , Frank Rudzicz , Marzyeh Ghassemi

In this paper, we combined linguistic complexity and (dis)fluency features with pretrained language models for the task of Alzheimer's disease detection of the 2021 ADReSSo (Alzheimer's Dementia Recognition through Spontaneous Speech)…

计算与语言 · 计算机科学 2021-06-17 Yu Qiao , Xuefeng Yin , Daniel Wiechmann , Elma Kerz

Early detection of Alzheimer's Disease (AD) is greatly beneficial to AD patients, leading to early treatments that lessen symptoms and alleviating financial burden of health care. As one of the leading signs of AD, language capability…

计算与语言 · 计算机科学 2025-10-17 Yangyang Li

Robust strategies for Alzheimer's disease (AD) detection are important, given the high prevalence of AD. In this paper, we study the performance and generalizability of three approaches for AD detection from speech on the recent ADReSSo…

计算与语言 · 计算机科学 2022-09-16 Aparna Balagopalan , Jekaterina Novikova

Alzheimer's Disease (AD) has become an increasingly critical global health concern, which necessitates effective monitoring solutions in smart health applications. However, the development of such solutions is significantly hindered by the…

机器学习 · 计算机科学 2025-03-04 Heming Fu , Hongkai Chen , Shan Lin , Guoliang Xing

Alzheimer's Disease (AD) is a complex neurodegenerative disorder marked by memory loss, executive dysfunction, and personality changes. Early diagnosis is challenging due to subtle symptoms and varied presentations, often leading to…

计算机视觉与模式识别 · 计算机科学 2025-01-06 Yifei Chen , Shenghao Zhu , Zhaojie Fang , Chang Liu , Binfeng Zou , Yuhe Wang , Shuo Chang , Fan Jia , Feiwei Qin , Jin Fan , Yong Peng , Changmiao Wang

Alzheimer's disease (AD) is the most prevalent form of dementia, and its early diagnosis is essential for slowing disease progression. Recent studies on multimodal neuroimaging fusion using MRI and PET have achieved promising results by…

计算机视觉与模式识别 · 计算机科学 2025-11-05 Delin Ma , Menghui Zhou , Jun Qi , Yun Yang , Po Yang

Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by the progressive accumulation of misfolded proteins, leading to cognitive decline. This study presents a novel stochastic modelling approach to simulate the…

神经元与认知 · 定量生物学 2024-11-06 Alec MacIver , Hina Shaheen

Healthcare datasets present many challenges to both machine learning and statistics as their data are typically heterogeneous, censored, high-dimensional and have missing information. Feature selection is often used to identify the…

机器学习 · 计算机科学 2022-07-06 Annette Spooner , Gelareh Mohammadi , Perminder S. Sachdev , Henry Brodaty , Arcot Sowmya

Federated Learning (FL) enables multiple institutes to train models collaboratively without sharing private data. Current FL research focuses on communication efficiency, privacy protection, and personalization and assumes that the data of…

计算机视觉与模式识别 · 计算机科学 2024-06-18 Zhipeng Deng , Yuqiao Yang , Kenji Suzuki

Dementia is a progressive cognitive syndrome with Alzheimer's disease (AD) as the leading cause. Conversation-based AD detection offers a cost-effective alternative to clinical methods, as language dysfunction is an early biomarker of AD.…

计算与语言 · 计算机科学 2025-02-27 Arezo Shakeri , Mina Farmanbar , Krisztian Balog

Alzheimer's Disease (AD) is an irreversible neurodegenerative disease affecting 50 million people worldwide. Low-cost, accurate identification of key markers of AD is crucial for timely diagnosis and intervention. Language impairment is one…

计算与语言 · 计算机科学 2025-05-27 Tingyu Mo , Jacqueline C. K. Lam , Victor O. K. Li , Lawrence Y. L. Cheung

Accurate and early diagnosis of Alzheimer's disease (AD) is critical for effective intervention and requires integrating complementary information from multimodal neuroimaging data. However, conventional fusion approaches often rely on…

We present two multimodal fusion-based deep learning models that consume ASR transcribed speech and acoustic data simultaneously to classify whether a speaker in a structured diagnostic task has Alzheimer's Disease and to what degree,…

计算与语言 · 计算机科学 2021-07-01 Morteza Rohanian , Julian Hough , Matthew Purver

Neuropsychiatric disorders, such as Alzheimer's disease (AD), depression, and autism spectrum disorder (ASD), are characterized by linguistic and acoustic abnormalities, offering potential biomarkers for early detection. Despite the promise…

计算与语言 · 计算机科学 2025-12-25 Zhongren Dong , Haotian Guo , Weixiang Xu , Huan Zhao , Zixing Zhang

Alzheimer's disease (AD) presents a complex, multifaceted challenge to patients, caregivers, and the healthcare system, necessitating integrated and dynamic support solutions. While artificial intelligence (AI) offers promising avenues for…

多智能体系统 · 计算机科学 2025-10-13 Adib Bazgir , Amir Habibdoust , Xing Song , Yuwen Zhang

Alzheimer's disease (AD) is a neurodegenerative disease that affects nearly 50 million individuals across the globe and is one of the leading causes of deaths globally. It is projected that by 2050, the number of people affected by the…

机器学习 · 计算机科学 2021-10-26 Yash Kumar , Piyush Maheshwari , Shreyansh Joshi , Veeky Baths

Background: Alzheimer's disease and related dementias (ADRD) are progressive neurodegenerative conditions where early detection is vital for timely intervention and care. Spontaneous speech contains rich acoustic and linguistic markers that…

计算与语言 · 计算机科学 2025-06-16 Jingyu Li , Lingchao Mao , Hairong Wang , Zhendong Wang , Xi Mao , Xuelei Sherry Ni