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Recent advances in large language models have enabled AI systems to achieve expert-level performance on domain-specific scientific tasks, yet these systems remain narrow and handcrafted. We introduce SciAgent, a unified multi-agent system…

Predicting the responses of a cell under perturbations may bring important benefits to drug discovery and personalized therapeutics. In this work, we propose a novel graph variational Bayesian causal inference framework to predict a cell's…

Autonomous agents driven by Large Language Models (LLMs) offer enormous potential for automation. Early proof of this technology can be found in various demonstrations of agents solving complex tasks, interacting with external systems to…

The increasing complexity of regulatory updates from global authorities presents significant challenges for medical device manufacturers, necessitating agile strategies to sustain compliance and maintain market access. Concurrently,…

人工智能 · 计算机科学 2024-12-24 Yu Han , Zekun Guo

Medication recommendation predicts medications for patient visits, but existing methods still face two key challenges. At the model level, traditional drug recommendation methods only predict structured drug codes with limited evidence…

计算与语言 · 计算机科学 2026-05-29 Xinyu Wang , Hanwei Wu , Zhenghan Tai , Sicheng Lyu , Qincheng Lu , Ziyu Zhao , Jijun Chi , Jingrui Tian , Xiao-Wen Chang , Ziyang Song

As large language models (LLMs) transition from static tools to fully agentic systems, their potential for transforming social science research has become increasingly evident. This paper introduces a structured framework for understanding…

多智能体系统 · 计算机科学 2026-05-19 Jennifer Haase , Sebastian Pokutta

We present a new experimental-computational technology of inferring network models that predict the response of cells to perturbations and that may be useful in the design of combinatorial therapy against cancer. The experiments are…

Urban causal research is essential for understanding the complex, dynamic processes that shape cities and for informing evidence-based policies. However, current practices are often constrained by inefficient and biased hypothesis…

Proactive agents that anticipate user intentions without explicit prompts represent a significant evolution in human-AI interaction, promising to reduce cognitive load and streamline workflows. However, existing datasets suffer from two…

人机交互 · 计算机科学 2026-02-11 Yuanbo Tang , Huaze Tang , Tingyu Cao , Lam Nguyen , Anping Zhang , Xinwen Cao , Chunkang Liu , Wenbo Ding , Yang Li

The concept of the 'agent' has profoundly shaped Artificial Intelligence (AI) research, guiding development from foundational theories to contemporary applications like Large Language Model (LLM)-based systems. This paper critically…

人工智能 · 计算机科学 2025-09-16 Jesse Gardner , Vladimir A. Baulin

Large Language Model (LLM)-based agents have recently shown impressive capabilities in complex reasoning and tool use via multi-step interactions with their environments. While these agents have the potential to tackle complicated tasks,…

Large Language Models have recently gained significant attention in scientific discovery for their extensive knowledge and advanced reasoning capabilities. However, they encounter challenges in effectively simulating observational feedback…

Large language models (LLMs) have shown promise in medical domains, but their ability to handle specialized neurological reasoning requires systematic evaluation. We developed a comprehensive benchmark using 305 questions from Israeli Board…

信息检索 · 计算机科学 2025-08-21 Moran Sorka , Alon Gorenshtein , Dvir Aran , Shahar Shelly

Personalized digital health support requires long-horizon, cross-dimensional reasoning over heterogeneous lifestyle signals, and recent advances in mobile sensing and large language models (LLMs) make such support increasingly feasible.…

人工智能 · 计算机科学 2026-01-21 Ye Tian , Zihao Wang , Onat Gungor , Xiaoran Fan , Tajana Rosing

Large language models (LLMs) exhibit strong symbolic and compositional reasoning, yet they struggle with time series question answering as the data is typically transformed into an LLM-compatible modality, e.g., serialized text, plotted…

Recent advances in large language models (LLMs) have enabled a new class of AI agents that automate multiple stages of the data science workflow by integrating planning, tool use, and multimodal reasoning across text, code, tables, and…

Large-scale telecom and datacenter infrastructures rely on multi-layered service and resource models, where failures propagate across physical and logical components and affect multiple customers. Traditional approaches to root cause…

人工智能 · 计算机科学 2026-01-13 Nicolas Tacheny

Despite the wealth of single-cell multi-omics data, it remains challenging to predict the consequences of novel genetic and chemical perturbations in the human body. It requires knowledge of molecular interactions at all biological levels,…

人工智能 · 计算机科学 2025-01-22 You Wu , Lei Xie

Proactive large language model (LLM) agents aim to actively plan, query, and interact over multiple turns, enabling efficient task completion beyond passive instruction following and making them essential for real-world, user-centric…

人工智能 · 计算机科学 2026-02-13 Yihang Yao , Zhepeng Cen , Haohong Lin , Shiqi Liu , Zuxin Liu , Jiacheng Zhu , Zhang-Wei Hong , Laixi Shi , Ding Zhao

Accurate prediction of traffic crash severity is critical for improving emergency response and public safety planning. Although recent large language models (LLMs) exhibit strong reasoning capabilities, their single-agent architectures…

人工智能 · 计算机科学 2026-02-03 Zhichao Yang , Jiashu He , Jinxuan Fan , Cirillo Cinzia