相关论文: Introns and Templates Matter: Rethinking Linkage i…
Graphical Transformation Models (GTMs) are introduced as a novel approach to effectively model multivariate data with intricate marginals and complex dependency structures semiparametrically, while maintaining interpretability through the…
The best-performing models in ML are not interpretable. If we can explain why they outperform, we may be able to replicate these mechanisms and obtain both interpretability and performance. One example are decision trees and their…
Fine-tuning large language models (LLMs) is computationally intensive because it requires updating all parameters. Low-Rank Adaptation (LoRA) improves efficiency by modifying only a subset of weights but introduces a trade-off between…
Gating mechanisms have emerged as an effective strategy integrated into model designs beyond recurrent neural networks for addressing long-range dependency problems. In a broad understanding, it provides adaptive control over the…
Gaussian processes (GPs) are powerful but computationally expensive machine learning models, requiring an estimate of the kernel covariance matrix for every prediction. In large and complex domains, such as graphs, sets, or images, the…
Knowledge graph representation learning approaches provide a mapping between symbolic knowledge in the form of triples in a knowledge graph (KG) and their feature vectors. Knowledge graph embedding (KGE) models often represent relations in…
A major goal in genomics is to properly capture the complex dynamical behaviors of gene regulatory networks (GRNs). This includes inferring the complex interactions between genes, which can be used for a wide range of genomics analyses,…
Decision-making in complex systems often relies on machine learning models, yet highly accurate models such as XGBoost and neural networks can obscure the reasoning behind their predictions. In operations research applications,…
Language models typically need to be trained or finetuned in order to acquire new knowledge, which involves updating their weights. We instead envision language models that can simply read and memorize new data at inference time, thus…
In recent years, large language models (LLMs) have achieved state-of-the-art results in various biological sequence analysis tasks, such as sequence classification, structure prediction, and function prediction. Similar to advancements in…
Machine learning is often applied in health science to obtain predictions and new understandings of complex phenomena and relationships, but an availability of sufficient data for model training is a widespread problem. Traditional machine…
Geometric morphometrics (GMM) is widely used to quantify shape variation, more recently serving as input for machine learning (ML) analyses. Standard practice aligns all specimens via Generalized Procrustes Analysis (GPA) prior to splitting…
Reward modeling has emerged as a crucial component in aligning large language models with human values. Significant attention has focused on using reward models as a means for fine-tuning generative models. However, the reward models…
Inferring latent interaction structures from observed dynamics is a fundamental inverse problem in many-body interacting systems. Most neural approaches rely on black-box surrogates over trainable graphs, achieving accuracy at the expense…
Natural language generation provides designers with methods for automatically generating text, e.g. for creating summaries, chatbots and game content. In practise, text generators are often either learned and hard to interpret, or created…
Decoder-only language models have the ability to dynamically switch between various computational tasks based on input prompts. Despite many successful applications of prompting, there is very limited understanding of the internal mechanism…
Evaluating large language models (LLMs) on their linguistic reasoning capabilities is an important task to understand the gaps in their skills that may surface during large-scale adoption. In this work, we investigate the abilities of such…
Gaussian graphical models are often used to infer gene networks based on microarray expression data. Many scientists, however, have begun using high-throughput sequencing technologies to measure gene expression. As the resulting…
Missing data imputation is a critical challenge in various domains, such as healthcare and finance, where data completeness is vital for accurate analysis. Large language models (LLMs), trained on vast corpora, have shown strong potential…
Standard models of biologically realistic or biologically inspired reinforcement learning employ a global error signal, which implies the use of shallow networks. On the other hand, error backpropagation allows the use of networks with…