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Objective: The advent of High-Performance Computing (HPC) in recent years has led to its increasing use in brain study through computational models. The scale and complexity of such models are constantly increasing, leading to challenging…

Foundation models are transforming neuroscience but are often prohibitively large, data-hungry, and difficult to deploy. Here, we introduce BrainSymphony, a lightweight and parameter-efficient foundation model with plug-and-play integration…

定量方法 · 定量生物学 2026-02-13 Moein Khajehnejad , Forough Habibollahi , Devon Stoliker , Adeel Razi

Neuroscience research has expanded dramatically over the past 30 years by advancing standardization and tool development to support rigor and transparency. Consequently, the complexity of the data pipeline has also increased, hindering…

We present Brain Harmony (BrainHarmonix), the first multimodal brain foundation model that unifies structural morphology and functional dynamics into compact 1D token representations. The model was pretrained on two of the largest…

The rapid evolution of artificial intelligence (AI) has shifted from static, data-driven models to dynamic systems capable of perceiving and interacting with real-world environments. Despite advancements in pattern recognition and symbolic…

We present a multi-scale differentiable brain modeling workflow utilizing BrainPy, a unique differentiable brain simulator that combines accurate brain simulation with powerful gradient-based optimization. We leverage this capability of…

神经与进化计算 · 计算机科学 2024-09-26 Chaoming Wang , Muyang Lyu , Tianqiu Zhang , Sichao He , Si Wu

Neuromorphic computing seeks to replicate the remarkable efficiency, flexibility, and adaptability of the human brain in artificial systems. Unlike conventional digital approaches, which suffer from the Von Neumann bottleneck and depend on…

人工智能 · 计算机科学 2025-11-04 Marcel van Gerven

For decades, neuroscientists and computer scientists have pursued a shared ambition: to understand intelligence and build it. Modern artificial neural networks now rival humans in language, perception, and reasoning, yet it is still largely…

Foundation models in artificial intelligence (AI) are transforming medical imaging by enabling general-purpose feature learning from large-scale, unlabeled datasets. In this work, we introduce BrainFound, a self-supervised foundation model…

计算机视觉与模式识别 · 计算机科学 2026-01-01 Moona Mazher , Geoff J. M. Parker , Daniel C. Alexander

Foundation models pretrained on large-scale datasets via self-supervised learning demonstrate exceptional versatility across various tasks. Due to the heterogeneity and hard-to-collect medical data, this approach is especially beneficial…

计算工程、金融与科学 · 计算机科学 2024-03-05 Yanwu Yang , Chenfei Ye , Guinan Su , Ziyao Zhang , Zhikai Chang , Hairui Chen , Piu Chan , Yue Yu , Ting Ma

Neuromorphic devices represent an attempt to mimic aspects of the brain's architecture and dynamics with the aim of replicating its hallmark functional capabilities in terms of computational power, robust learning and energy efficiency. We…

As humans advance toward a higher level of artificial intelligence, it is always at the cost of escalating computational resource consumption, which requires developing novel solutions to meet the exponential growth of AI computing demand.…

Brain foundation models (BFMs) have emerged as a transformative paradigm in computational neuroscience, offering a revolutionary framework for processing diverse neural signals across different brain-related tasks. These models leverage…

机器学习 · 计算机科学 2025-07-22 Xinliang Zhou , Chenyu Liu , Zhisheng Chen , Kun Wang , Yi Ding , Ziyu Jia , Qingsong Wen

Biological neural networks are often modeled as systems of coupled, nonlinear, ordinary or partial differential equations. The number of differential equations used to model a network increases with the size of the network and the level of…

神经元与认知 · 定量生物学 2022-08-09 Rishika Mohanta , Collins Assisi

Multimodal learning enhances the perceptual capabilities of cognitive systems by integrating information from different sensory modalities. However, existing multimodal fusion research typically assumes static integration, not fully…

神经与进化计算 · 计算机科学 2025-05-16 Xiang He , Dongcheng Zhao , Yang Li , Qingqun Kong , Xin Yang , Yi Zeng

Current multimodal medical image fusion typically assumes that source images are of high quality and perfectly aligned at the pixel level. Its effectiveness heavily relies on these conditions and often deteriorates when handling misaligned…

计算机视觉与模式识别 · 计算机科学 2025-07-01 Dayong Su , Yafei Zhang , Huafeng Li , Jinxing Li , Yu Liu

Neural network frameworks such as PyTorch and TensorFlow are the workhorses of numerous machine learning applications ranging from object recognition to machine translation. While these frameworks are versatile and straightforward to use,…

分布式、并行与集群计算 · 计算机科学 2018-04-24 Nicolas Weber , Florian Schmidt , Mathias Niepert , Felipe Huici
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