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Purpose: In recent years, Non-Local based methods have been successfully applied to lung nodule classification. However, these methods offer 2D attention or limited 3D attention to low-resolution feature maps. Moreover, they still depend on…

While deep learning methods are increasingly being applied to tasks such as computer-aided diagnosis, these models are difficult to interpret, do not incorporate prior domain knowledge, and are often considered as a "black-box." The lack of…

The 3D simulation model of the lung was established by using the reconstruction method. A computer aided pulmonary nodule detection model was constructed. The process iterates over the images to refine the lung nodule recognition model…

Purpose: To develop high throughput multi-label annotators for body (chest, abdomen, and pelvis) Computed Tomography (CT) reports that can be applied across a variety of abnormalities, organs, and disease states. Approach: We used a…

Pre-trained deep language models~(LM) have advanced the state-of-the-art of text retrieval. Rerankers fine-tuned from deep LM estimates candidate relevance based on rich contextualized matching signals. Meanwhile, deep LMs can also be…

Deep learning-based segmentation and classification are crucial to large-scale biomedical imaging, particularly for 3D data, where manual analysis is impractical. Although many methods exist, selecting suitable models and tuning parameters…

The delivery of appropriate targeted therapies to cancer patients requires the complete analysis of the molecular profiling of tumors and the patient's clinical characteristics in the context of existing knowledge and recent findings…

Lung cancer is the leading cause of cancer-related death worldwide. Early diagnosis of pulmonary nodules in Computed Tomography (CT) chest scans provides an opportunity for designing effective treatment and making financial and care plans.…

Accurate segmentation for medical images is important for clinical diagnosis. Existing automatic segmentation methods are mainly based on fully supervised learning and have an extremely high demand for precise annotations, which are very…

Recent advances in named entity recognition (NER) have pushed the boundary of the task to incorporate visual signals, leading to many variants, including multi-modal NER (MNER) or grounded MNER (GMNER). A key challenge to these tasks is…

Since radiologists have different training and clinical experiences, they may provide various segmentation annotations for a lung nodule. Conventional studies choose a single annotation as the learning target by default, but they waste…

Clinical information extraction (e.g., 2010 i2b2/VA challenge) usually presents tasks of concept recognition, assertion classification, and relation extraction. Jointly modeling the multi-stage tasks in the clinical domain is an…

Computed tomography (CT) generates a stack of cross-sectional images covering a region of the body. The visual assessment of these images for the identification of potential abnormalities is a challenging and time consuming task due to the…

Lung cancer remains one of the leading causes of cancer-related mortality worldwide. Conventional computed tomography (CT) imaging, while essential for detection and staging, has limitations in distinguishing benign from malignant lesions…

We propose a novel Deep Active Learning (DeepAL) model-3D Wasserstein Discriminative UNet (WD-UNet) for reducing the annotation effort of medical 3D Computed Tomography (CT) segmentation. The proposed WD-UNet learns in a semi-supervised way…

While microscopic analysis of histopathological slides is generally considered as the gold standard method for performing cancer diagnosis and grading, the current method for analysis is extremely time consuming and labour intensive as it…

In this study, we propose a lung nodule detection scheme which fully incorporates the clinic workflow of radiologists. Particularly, we exploit Bi-Directional Maximum intensity projection (MIP) images of various thicknesses (i.e., 3, 5 and…

Efforts to utilize growing volumes of clinical imaging data to generate tumor evaluations continue to require significant manual data wrangling owing to the data heterogeneity. Here, we propose an artificial intelligence-based solution for…

Interpretability is often an essential requirement in medical imaging. Advanced deep learning methods are required to address this need for explainability and high performance. In this work, we investigate whether additional information…

The efficacy of Multimodal Transformers in visually-rich document understanding (VrDU) is critically constrained by two inherent limitations: the lack of explicit modeling for logical reading order and the interference of visual tokens that…