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Long-term outcomes of experimental evaluations are necessarily observed after long delays. We develop semiparametric methods for combining the short-term outcomes of experiments with observational measurements of short-term and long-term…

计量经济学 · 经济学 2023-08-21 Jiafeng Chen , David M. Ritzwoller

Patient-reported outcome (PRO) measures are increasingly collected as a means of measuring healthcare quality and value. The capability to predict such measures enables patient-provider shared decision making and the delivery of…

统计方法学 · 统计学 2023-03-01 Jaeyoung Park , Muxuan Liang , Ying-Qi Zhao , Xiang Zhong

We develop a novel method for personalized off-policy learning in scenarios with unobserved confounding. Thereby, we address a key limitation of standard policy learning: standard policy learning assumes unconfoundedness, meaning that no…

机器学习 · 计算机科学 2026-02-18 Konstantin Hess , Dennis Frauen , Valentyn Melnychuk , Stefan Feuerriegel

Observational studies are the primary source of data for causal inference, but it is challenging when existing unmeasured confounding. Missing data problems are also common in observational studies. How to obtain the causal effects from the…

统计方法学 · 统计学 2023-05-15 Renzhong Zheng

One of the major challenges in estimating conditional potential outcomes and conditional average treatment effects (CATE) is the presence of hidden confounders. Since testing for hidden confounders cannot be accomplished only with…

机器学习 · 计算机科学 2025-06-17 Ahmed Aloui , Juncheng Dong , Ali Hasan , Vahid Tarokh

Given only data generated by a standard confounding graph with unobserved confounder, the Average Treatment Effect (ATE) is not identifiable. To estimate the ATE, a practitioner must then either (a) collect deconfounded data;(b) run a…

机器学习 · 统计学 2021-03-09 Kyra Gan , Andrew A. Li , Zachary C. Lipton , Sridhar Tayur

We consider estimation and inference of the effects of a policy in the absence of an untreated or control group. We obtain unbiased estimators of individual (heterogeneous) treatment effects and a consistent and asymptotically normal…

计量经济学 · 经济学 2026-01-13 Irene Botosaru , Raffaella Giacomini , Martin Weidner

In this paper, we develop a semiparametric sensitivity analysis approach designed to address unmeasured confounding in observational studies with time-to-event outcomes. We target estimation of the marginal distributions of potential…

统计方法学 · 统计学 2025-11-21 Linda Amoafo , Shiyao Xu , Elizabeth Platz , Daniel Scharfstein

Although randomized experiments are widely regarded as the gold standard for estimating causal effects, missing data of the pretreatment covariates makes it challenging to estimate the subgroup causal effects. When the missing data…

统计理论 · 数学 2014-01-08 Peng Ding , Zhi Geng

Unobserved confounding is a key challenge when estimating causal effects from a treatment on an outcome in scientific applications. In this work, we assume that we observe a single, potentially multi-dimensional proxy variable of the…

机器学习 · 统计学 2026-04-13 Silvan Vollmer , Niklas Pfister , Sebastian Weichwald

Off-policy evaluation of sequential decision policies from observational data is necessary in applications of batch reinforcement learning such as education and healthcare. In such settings, however, unobserved variables confound observed…

机器学习 · 计算机科学 2020-07-14 Nathan Kallus , Angela Zhou

Identifying causal treatment (or exposure) effects in observational studies requires the data to satisfy the unconfoundedness assumption which is not testable using the observed data. With sensitivity analysis, one can determine how the…

统计方法学 · 统计学 2023-01-31 Yang Ou , Lu Tang , Chung-Chou H. Chang

When observed decisions depend only on observed features, off-policy policy evaluation (OPE) methods for sequential decision making problems can estimate the performance of evaluation policies before deploying them. This assumption is…

机器学习 · 统计学 2020-03-13 Hongseok Namkoong , Ramtin Keramati , Steve Yadlowsky , Emma Brunskill

We propose robust methods for inference on the effect of a treatment variable on a scalar outcome in the presence of very many controls. Our setting is a partially linear model with possibly non-Gaussian and heteroscedastic disturbances.…

统计方法学 · 统计学 2017-10-05 Alexandre Belloni , Victor Chernozhukov , Christian Hansen

Causal discovery from data affected by unobserved variables is an important but difficult problem to solve. The effects that unobserved variables have on the relationships between observed variables are more complex in nonlinear cases than…

机器学习 · 计算机科学 2021-06-07 Takashi Nicholas Maeda , Shohei Shimizu

Sensitivity analysis for unmeasured confounding under incremental propensity score interventions remains relatively underdeveloped. Incremental interventions define stochastic treatment regimes by multiplying the odds of treatment, offering…

统计方法学 · 统计学 2026-01-27 Shuying Shen , Valerio Bacak , Edward H. Kennedy

Surrogate endpoints are often used in place of expensive, delayed, or rare true endpoints in clinical trials. However, regulatory authorities require thorough evaluation to accept these surrogate endpoints as reliable substitutes. One…

统计方法学 · 统计学 2024-10-08 Gokce Deliorman , Florian Stijven , Wim Van der Elst , Maria del Carmen Pardo , Ariel Alonso

Performing causal inference in observational studies requires we assume confounding variables are correctly adjusted for. G-computation methods are often used in these scenarios, with several recent proposals using Bayesian versions of…

统计方法学 · 统计学 2021-10-25 Daniel Daly-Grafstein , Paul Gustafson

Causal inference is difficult in the presence of unobserved confounders. We introduce the instrumented common confounding (ICC) approach to (nonparametrically) identify causal effects with instruments, which are exogenous only conditional…

计量经济学 · 经济学 2022-09-20 Christian Tien

We propose a method for estimating long-term treatment effects with many short-term proxy outcomes: a central challenge when experimenting on digital platforms. We formalize this challenge as a latent variable problem where observed proxies…

计量经济学 · 经济学 2026-01-13 Apoorva Lal , Guido Imbens , Peter Hull