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Formation of bacterial colonies as biofilm on the surface/interface of various objects has the potential to impact not only human health and disease but also energy and environmental considerations. Biofilms can be regarded as soft…

流体动力学 · 物理学 2015-09-15 Pallab Barai , Aloke Kumar , Partha P. Mukherjee

We focused on polydimethylsiloxane (PDMS) as a substrate for replication, micropatterning, and construction of biologically active surfaces. The novelty of this study is based on the combina-tion of argon plasma exposure of micropatterned…

We derive a physiologically structured multiscale model for biofilm development. The model has components on two spatial scales, which induce different time scales into the problem. The macroscopic behavior of the system is modeled using…

细胞行为 · 定量生物学 2023-02-14 Bruce P. Ayati , Isaac Klapper

The anchoring biofilm layer is expected to exhibit a different response to environmental stresses than for portions in the bulk, due to the protection from other strata and the proximity to the attachment surface. The effect of hydrodynamic…

生物物理 · 物理学 2021-10-22 Mirpouyan Zarabadi , François Paquet-Mercier , Steve J. Charette , Jesse Greener

Soft surfaces, spanning vastly different environmental and biomedical settings, are frequently colonised by surface-associated bacteria. Yet, how soft surfaces govern bacterial dynamics and their self-organisation into colonies remains…

生物物理 · 物理学 2025-12-29 Garima Rani , G. H. Philipp Nguyen , René Wittmann , Hartmut Löwen , Anupam Sengupta

The present paper proposes a novel method of quantification of the variation in biofilm architecture, in correlation with the alteration of growth conditions that include, variations of substrate and conditioning layer. The polymeric…

生物物理 · 物理学 2018-01-30 Suparna Dutta Sinha , Saptarshi Das , Sujata Tarafdar , Tapati Dutta

Bacterial communities such as biofilms are widely recognised as being important for survival and persistence of bacteria in harsh environments. Mechanistic models of biofilm growth indicate that the way in which the surface is seeded can…

定量方法 · 定量生物学 2007-05-23 Leah R. Johnson

How morphogenesis depends on cell properties is an active direction of research. Here, we focus on mechanical models of growing plant tissues, where microscopic (sub)cellular structure is taken into account. In order to establish links…

偏微分方程分析 · 数学 2023-11-21 Arezki Boudaoud , Annamaria Kiss , Mariya Ptashnyk

A distinguishing feature of a multicellular living system is that it operates at various scales, from the intracellular to organismal. Very little is known at present on how tissue level properties are related to cell and subcellular…

生物物理 · 物理学 2007-06-26 Elijah Flenner , Francoise Marga , Adrian Neagu , Ioan Kosztin , Gabor Forgacs

Multiscale phenomena exhibit complex structure-function relationships, and predicting their macroscopic behavior requires deducing differential equations at different scales. The complexity of these equations and the number of essential…

数学物理 · 物理学 2023-07-25 Vincenzo Fazio , Nicola Maria Pugno , Orazio Giustolisi , Giuseppe Puglisi

Many bacterial species readily develop biofilms that act as a protective matrix against external challenge, e.g. from antimicrobial treatment. Therefore, biofilms are often responsible for persistent and recurring infections. Established…

Inter-surface forces mediated by polymer films are important in a range of technological and industrial situations. In cosmetics, applications such as hair conditioning typically rely on the adsorption of polyelectrolyte films onto the…

软凝聚态物质 · 物理学 2025-04-03 Lionel Bureau , Simon Trouille , Gustavo S Luengo

Inspired by the natural defence strategies of insect wings and plant leaves, nanostructured surfaces have emerged as a promising tool in various fields, including engineering, biomedical sciences, and materials science to combat bacterial…

生物物理 · 物理学 2025-03-04 Vladimir A. Baulin , Denver P. Linklater , Saulius Juodkazis , Elena P. Ivanova

Soft solids and their surface deformations control the response of many natural and artificial systems. Yet, their underlying properties are vigorously debated, particularly for polymer networks. While molecular-scale theories predict no…

From multicellular tissues to bacterial colonies, three dimensional cellular structures arise through the interaction of cellular activities and mechanical forces. Simple bacterial communities provide model systems for analyzing such…

软凝聚态物质 · 物理学 2024-01-11 Ana Carpio , Elena Cebrian , David R. Espeso , Perfecto Vidal

For three-dimensional mono-layer molecularly thin-film lubrication, it is found that elasticity of the substrate affects tribological behaviors of a thin fluid film confined by two solid substrates.To account for the elastic effects, a…

化学物理 · 物理学 2023-06-16 Zuo-Bing Wu

Constructing a surface that is an integral part of the function of tribosystems (deterministic surface) is an intriguing goal. Inspirations for such surfaces come from studying natural systems and deducing design rules. The major attraction…

生物物理 · 物理学 2010-01-28 H. A. Abdel-Aal , M. El Mansori , S. Mezghani

Molecular-scale interactions between solvated macromolecules and solid surfaces govern a large number of processes, from biology to engineering. Yet, despite extensive characterization at the macroscopic level, our molecular understanding…

软凝聚态物质 · 物理学 2026-05-07 Malo Velay , Jean Comtet

Biomaterial surface engineering and integrating cell-adhesive ligands are crucial in biological research and biotechnological applications. The interplay between cells and their microenvironment, influenced by chemical and physical cues,…

The structure and degree of order in soft matter and other materials is intimately connected to the nature of the interactions between the particles. One important research goal is to find suitable control mechanisms, to enhance or suppress…

软凝聚态物质 · 物理学 2020-09-16 A. Scacchi , M. G. Mazza , A. J. Archer
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