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Background - Pulmonary insufficiency is a consequence of transannular patch repair in Tetralogy of Fallot (ToF), leading to late morbidity and mortality. Transcatheter native outflow tract pulmonary valve replacement (TPVR) has become…

Advances in three-dimensional imaging provide the ability to construct and analyze finite element (FE) models to evaluate the biomechanical behavior and function of atrioventricular valves. However, while obtaining patient-specific valve…

This work reports on a study to develop a patient-specific finite element model of the Transcatheter Aortic Valve Implantation procedure, using a model of a balloon-expandable percutaneous prosthetic aortic valve as a framework for the…

医学物理 · 物理学 2019-10-02 Mehdi Shirzadi , B. Daya Reddy , Harish Appa

Reversible pump turbines are praised for their operational flexibility leading to their recent wide adoption within pumped storage hydropower plants. However, frequently imposed off-design operating conditions in these plants give rise to…

流体动力学 · 物理学 2023-10-18 Maxime Binama , Kan Kan , Hui-Xiang Chen , Yuan Zheng , Daqing Zhou , Wen-Tao Su , Alexis Muhirwa , James Ntayomba

Tissue-engineered vascular grafts (TEVG) have shown promise in advancing vascular reconstructions. However, precise in vivo implantation is challenging, and it is unclear how deviations in location and size affect hemodynamics. This study…

We report three-dimensional and time-dependent numerical simulations of the propagation of electrical action potentials in a model of rabbit ventricular tissue. The simulations are performed using a finite-element method for the solution of…

定量方法 · 定量生物学 2021-05-20 Peter Mortensen , Muhamad H. N. Aziz , Hao Gao , Radostin D. Simitev

Air entrapment during mold filling critically affects porosity and overall casting quality in High Pressure Die Casting. This study assesses the feasibility of applying the vof method within OpenFOAM to simulate compressible, turbulent mold…

流体动力学 · 物理学 2026-01-22 Mehran Shazedeh , Fabian Teichmann , Sebastian Müller

Purpose: Transcatheter edge-to-edge repair (TEER) and annuloplasty devices are increasingly used to treat mitral valve regurgitation, yet their mechanical effects and interactions remain poorly understood. This study aimed to establish an…

Hepatic fibrosis causes an increase in liver stiffness, a parameter measured by elastography and widely used as a diagnosis method. The concomitant presence of portal vein thrombosis (PVT) implies a change in hepatic portal inflow that…

The simulation of a short fibre reinforced structure by means of the FEM requires the knowledge of the material behaviour at every Gauss point. In order to obtain such information, a representative volume element (RVE) containing…

材料科学 · 物理学 2014-08-21 N. Goldberg , H. Donner , J. Ihlemann

Stress concentration due to flaws in any material are very dangerous. Its understanding is thus very important before practical application of the material. As Fiber Reinforced Composite (FRC) is gaining wide range of application it is…

应用物理 · 物理学 2022-09-20 A. V. Sirsat , S. S Padhee

In this study, we delve into the intricacies of elastoviscoplastic (EVP) fluids, particularly focusing on how polymer additives influence their extensional behavior. Our findings reveal that polymer additives significantly alter the…

流体动力学 · 物理学 2024-06-11 Mohamed S. Abdelgawad , Simon J. Haward , Amy Q. Shen , Marco E. Rosti

Accurate assessment of myocardial tissue stiffness is pivotal for the diagnosis and prognosis of heart diseases. Left ventricular diastolic stiffness ($\beta$) obtained from the end-diastolic pressure-volume relationship (EDPVR) has…

Myocardial infarction significantly degrades heart function, and current treatments can bring forth serious cost and complications including blood clots and infections. To improve the current state of treatment, researchers are developing…

We systematically investigate the influence of polyvinyl formal (PVFM), commonly known as Formvar, in comparison to polycarbonate (PC) and polymethyl methacrylate (PMMA), as encapsulation materials on the strain performance of MoS2…

This study investigates the influence of fiber spatial distribution on the transverse mechanical properties of unidirectionally reinforced continuous-fiber composites. A Swelling & Random Migration algorithm was employed to generate…

计算工程、金融与科学 · 计算机科学 2026-05-28 Sergejs Tarasovs , Janis Modniks , Andrea Bercini Martins , Christina Scheffler , Janis Andersons

We present a physics-based model that accurately predicts the performance of Medtronic's implantable medical device battery lithium/carbon monofluoride (CF$_x$) - silver vanadium oxide (SVO) under both low-rate background monitoring and…

Vertical field effect transistors (VOFETs) can offer short channel architecture which can further enhance the performance at low operating voltages which makes it more viable for organic electronics applications. VOFETs can be prepared with…

应用物理 · 物理学 2023-01-24 Ramesh Singh Bisht , Pramod Kumar

The left ventricular end-systolic pressure-volume relationship (ESPVr) is a key indicator of cardiac contractility. Despite its established importance, several studies suggested that the mechanical mode of contraction, such as isovolumetric…

医学物理 · 物理学 2024-11-12 Francesco Regazzoni , Corrado Poggesi , Cecilia Ferrantini

Introduction: Stenotic aortic valve disease (AS) causes pressure overload of the left ventricle (LV) that may trigger adverse remodeling and precipitate progression towards heart failure (HF). As myocardial energetics can be impaired during…

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