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Alzheimer's disease (AD) is a neurodegenerative disorder marked by memory loss and cognitive decline, making early detection vital for timely intervention. However, early diagnosis is challenging due to the heterogeneous presentation of…

神经元与认知 · 定量生物学 2025-09-24 Ali Khazaee , Abdolreza Mohammadi , Ruairi O'Reilly

Alzheimer's disease is estimated to affect around 50 million people worldwide and is rising rapidly, with a global economic burden of nearly a trillion dollars. This calls for scalable, cost-effective, and robust methods for detection of…

音频与语音处理 · 电气工程与系统科学 2020-09-03 Utkarsh Sarawgi , Wazeer Zulfikar , Nouran Soliman , Pattie Maes

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia, affecting memory, reasoning, communication, and daily functioning. Early diagnosis is particularly important, as timely intervention may…

声音 · 计算机科学 2026-05-26 Loukas Ilias , Dimitris Askounis

Alzheimer's disease is one of the diseases that mostly affects older people without being a part of aging. The most common symptoms include problems with communicating and abstract thinking, as well as disorientation. It is important to…

图像与视频处理 · 电气工程与系统科学 2020-12-01 Fatih Altay , Guillermo Ramon Sanchez , Yanli James , Stephen V. Faraone , Senem Velipasalar , Asif Salekin

At present, the vast majority of human subjects with neurological disease are still diagnosed through in-person assessments and qualitative analysis of patient data. In this paper, we propose to use Topological Data Analysis (TDA) together…

机器学习 · 计算机科学 2020-05-07 Afra Nawar , Farhan Rahman , Narayanan Krishnamurthi , Anirudh Som , Pavan Turaga

With the increasing amounts of high-dimensional heterogeneous data to be processed, multi-modality feature selection has become an important research direction in medical image analysis. Traditional methods usually depict the data structure…

计算机视觉与模式识别 · 计算机科学 2022-04-11 Yuang Shi , Chen Zu , Mei Hong , Luping Zhou , Lei Wang , Xi Wu , Jiliu Zhou , Daoqiang Zhang , Yan Wang

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and a major cause of dementia. Structural MRI is widely used to analyze AD-related brain atrophy; however, most deep learning methods rely on computationally expensive 3D…

计算机视觉与模式识别 · 计算机科学 2026-04-28 Towhidul Islam , Mufti Mahmud

Accurate and early diagnosis of Alzheimer's disease (AD) is critical for effective intervention and requires integrating complementary information from multimodal neuroimaging data. However, conventional fusion approaches often rely on…

Existing research has shown the potential of classifying Alzheimers Disease (AD) from eye-tracking (ET) data with classifiers that rely on task-specific engineered features. In this paper, we investigate whether we can improve on existing…

计算机视觉与模式识别 · 计算机科学 2023-09-25 Harshinee Sriram , Cristina Conati , Thalia Field

Alzheimer's disease (AD) is the most common long-term illness in elderly people. In recent years, deep learning has become popular in the area of medical imaging and has had a lot of success there. It has become the most effective way to…

计算机视觉与模式识别 · 计算机科学 2023-10-16 Mahin Khan Mahadi , Abdullah Abdullah , Jamal Uddin , Asif Newaz

Nowadays, due to tremendous improvements in high performance computing, it has become easier to train Neural Networks. We intend to take advantage of this situation and apply this technology in solving real world problems. There was a need…

计算机视觉与模式识别 · 计算机科学 2019-10-15 Gururaj Awate , Sunil Bangare , G Pradeepini , S Patil

Dementia is a neurological syndrome marked by cognitive decline. Alzheimer's disease (AD) and Frontotemporal dementia (FTD) are the common forms of dementia, each with distinct progression patterns. EEG, a non-invasive tool for recording…

信号处理 · 电气工程与系统科学 2024-08-21 Shivani Ranjan , Ayush Tripathi , Harshal Shende , Robin Badal , Amit Kumar , Pramod Yadav , Deepak Joshi , Lalan Kumar

Collecting and accessing a large amount of medical data is very time-consuming and laborious, not only because it is difficult to find specific patients but also because it is required to resolve the confidentiality of a patient's medical…

声音 · 计算机科学 2021-03-04 Junghyun Koo , Jie Hwan Lee , Jaewoo Pyo , Yujin Jo , Kyogu Lee

In the last decade, computer-aided early diagnostics of Alzheimer's Disease (AD) and its prodromal form, Mild Cognitive Impairment (MCI), has been the subject of extensive research. Some recent studies have shown promising results in the AD…

计算机视觉与模式识别 · 计算机科学 2018-09-12 Alexander Khvostikov , Karim Aderghal , Andrey Krylov , Gwenaelle Catheline , Jenny Benois-Pineau

More than 10.7% of people aged 65 and older are affected by Alzheimer's disease. Early diagnosis and treatment are crucial as most Alzheimer's patients are unaware of having it until the effects become detrimental. AI has been known to use…

图像与视频处理 · 电气工程与系统科学 2023-09-19 Audrey Paleczny , Shubham Parab , Maxwell Zhang

The identification of Alzheimer's disease (AD) and its early stages using structural magnetic resonance imaging (MRI) has been attracting the attention of researchers. Various data-driven approaches have been introduced to capture subtle…

人工智能 · 计算机科学 2021-08-11 Changhyun Park , Heung-Il Suk

Background: The increasing availability of databases containing both magnetic resonance imaging (MRI) and genetic data allows researchers to utilize multimodal data to better understand the characteristics of dementia of Alzheimer's type…

Predicting conversion from Mild Cognitive Impairment (MCI) to Alzheimer's Disease (AD) is critical for early intervention. Current deep learning paradigms predominantly rely on cross-sectional structural MRI, neglecting prognostic value in…

计算机视觉与模式识别 · 计算机科学 2026-05-28 Alireza Moayedikia , Sara Fin , Alicia Troncoso Lora , Uffe Kock Wiil

Identification of brain regions related to the specific neurological disorders are of great importance for biomarker and diagnostic studies. In this paper, we propose an interpretable Graph Convolutional Network (GCN) framework for the…

机器学习 · 计算机科学 2022-04-29 Houliang Zhou , Lifang He , Yu Zhang , Li Shen , Brian Chen