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Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…

计算机视觉与模式识别 · 计算机科学 2026-04-08 Yujian Xiong , Mohammad Farazi , Yanxi Chen , Wenhui Zhu , Xuanzhao Dong , Natasha Lepore , Yi Su , Raza Mushtaq , Stephen Foldes , Andrew Yang , Yalin Wang

Modern recommender systems face critical challenges in handling information overload while addressing the inherent limitations of multimodal representation learning. Existing methods suffer from three fundamental limitations: (1) restricted…

信息检索 · 计算机科学 2025-08-15 Zheyu Chen , Jinfeng Xu , Hewei Wang , Shuo Yang , Zitong Wan , Haibo Hu

Neurodegenerative diseases are frequently associated with structural changes in the brain. Magnetic Resonance Imaging (MRI) scans can show these variations and therefore be used as a supportive feature for a number of neurodegenerative…

We present a longitudinal MR simulation framework which simulates the future neurodegenerative progression by outputting the predicted follow-up MR image and the voxel-based morphometry (VBM) map. This framework expects the patients to have…

计算机视觉与模式识别 · 计算机科学 2015-08-25 Siqi Liu , Sidong Liu , Sonia Pujol , Ron Kikinis , Dagan Feng , Michael Fulham , Weidong Cai

Graph-based medical image segmentation represents anatomical structures using boundary graphs, providing fixed-topology landmarks and inherent population-level correspondences. However, their clinical adoption has been hindered by a major…

计算机视觉与模式识别 · 计算机科学 2026-02-25 Nicolás Gaggion , Maria J. Ledesma-Carbayo , Stergios Christodoulidis , Maria Vakalopoulou , Enzo Ferrante

The hippocampus is a seminal structure in the most common surgically-treated form of epilepsy. Accurate segmentation of the hippocampus aids in establishing asymmetry regarding size and signal characteristics in order to disclose the likely…

We present a robust method to find region-level correspondences between shapes, which are invariant to changes in geometry and applicable across multiple shape representations. We generate simplified shape graphs by jointly decomposing the…

图形学 · 计算机科学 2018-03-06 Yanir Kleiman , Maks Ovsjanikov

We introduce a framework combining geometric modeling with disease progression analysis to investigate tau deposition in Alzheimer's disease (AD) using positron emission tomography (PET) data. Focusing on the hippocampus, we construct a…

应用统计 · 统计学 2025-12-03 Liangkang Wang , Akhil Ambekar , Ani Eloyan

The study of physiology demonstrates that the form (shape)of anatomical structures dictates their functions, and analyzing the form of anatomies plays a crucial role in clinical research. Statistical shape modeling (SSM) is a widely used…

计算机视觉与模式识别 · 计算机科学 2024-07-03 Krithika Iyer , Shireen Y. Elhabian

Detection and segmentation of the hippocampal structures in volumetric brain images is a challenging problem in the area of medical imaging. In this paper, we propose a two-stage 3D fully convolutional neural network that efficiently…

计算机视觉与模式识别 · 计算机科学 2019-02-13 Dengsheng Chen , Wenxi Liu , You Huang , Tong Tong , Yuanlong Yu

The brain has computational capabilities that surpass those of modern systems, being able to solve complex problems efficiently in a simple way. Neuromorphic engineering aims to mimic biology in order to develop new systems capable of…

Understanding individual cortical development is essential for identifying deviations linked to neurodevelopmental disorders. However, current normative modelling frameworks struggle to capture fine-scale anatomical details due to their…

Statistical shape modeling (SSM) is a valuable and powerful tool to generate a detailed representation of complex anatomy that enables quantitative analysis and the comparison of shapes and their variations. SSM applies mathematics,…

图像与视频处理 · 电气工程与系统科学 2022-09-14 Krithika Iyer , Alan Morris , Brian Zenger , Karthik Karanth , Benjamin A Orkild , Oleksandre Korshak , Shireen Elhabian

Understanding the intricate mappings between visual stimuli and neural responses is a fundamental challenge in cognitive neuroscience. While current approaches predominantly align images and functional magnetic resonance imaging (fMRI)…

计算机视觉与模式识别 · 计算机科学 2026-05-12 Zihan Ma , Tian Xia , Kexin Wang , Xiao Li , Xiaowei He , Yudan Ren

Statistical shape modeling (SSM) characterizes anatomical variations in a population of shapes generated from medical images. SSM requires consistent shape representation across samples in shape cohort. Establishing this representation…

计算机视觉与模式识别 · 计算机科学 2022-03-17 Riddhish Bhalodia , Shireen Elhabian , Jadie Adams , Wenzheng Tao , Ladislav Kavan , Ross Whitaker

Significant advancements have been made in developing parametric models for digital humans, with various approaches concentrating on parts such as the human body, hand, or face. Nevertheless, connectors such as the neck have been overlooked…

图形学 · 计算机科学 2023-05-09 Longwen Zhang , Zijun Zhao , Xinzhou Cong , Qixuan Zhang , Shuqi Gu , Yuchong Gao , Rui Zheng , Wei Yang , Lan Xu , Jingyi Yu

In clinical applications, the utility of segmentation models is often based on the accuracy of derived downstream metrics such as organ size, rather than by the pixel-level accuracy of the segmentation masks themselves. Thus, uncertainty…

图像与视频处理 · 电气工程与系统科学 2026-03-03 Matt Y. Cheung , Ashok Veeraraghavan , Guha Balakrishnan

We introduce a new regression framework designed to deal with large-scale, complex data that lies around a low-dimensional manifold with noises. Our approach first constructs a graph representation, referred to as the skeleton, to capture…

机器学习 · 计算机科学 2026-03-17 Zeyu Wei , Yen-Chi Chen

In order to thrive in hostile and ever-changing natural environments, mammalian brains evolved to store large amounts of knowledge about the world and continually integrate new information while avoiding catastrophic forgetting. Despite the…

计算与语言 · 计算机科学 2025-01-15 Bernal Jiménez Gutiérrez , Yiheng Shu , Yu Gu , Michihiro Yasunaga , Yu Su

Modeling 3D humans accurately and robustly from a single image is very challenging, and the key for such an ill-posed problem is the 3D representation of the human models. To overcome the limitations of regular 3D representations, we…

计算机视觉与模式识别 · 计算机科学 2020-12-16 Zerong Zheng , Tao Yu , Yebin Liu , Qionghai Dai