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Histopathology, the current gold standard for cancer diagnosis, involves the manual examination of tissue samples after chemical staining, a time-consuming process requiring expert analysis. Raman spectroscopy is an alternative, stain-free…

Imaging through scattering is a pervasive and difficult problem in many biological applications. The high background and the exponentially attenuated target signals due to scattering fundamentally limits the imaging depth of fluorescence…

信号处理 · 电气工程与系统科学 2023-12-11 Jeffrey Alido , Joseph Greene , Yujia Xue , Guorong Hu , Yunzhe Li , Mitchell Gilmore , Kevin J. Monk , Brett T. DiBenedictis , Ian G. Davison , Lei Tian

Recently, the mainstream practice for training low-light raw image denoising methods has shifted towards employing synthetic data. Noise modeling, which focuses on characterizing the noise distribution of real-world sensors, profoundly…

图像与视频处理 · 电气工程与系统科学 2026-01-16 Hansen Feng , Lizhi Wang , Yiqi Huang , Yuzhi Wang , Lin Zhu , Hua Huang

Noise reduction techniques based on deep learning have demonstrated impressive performance in enhancing the overall quality of recorded speech. While these approaches are highly performant, their application in audio engineering can be…

声音 · 计算机科学 2023-10-18 Christian J. Steinmetz , Thomas Walther , Joshua D. Reiss

Image restoration has been an extensively researched topic in numerous fields. With the advent of deep learning, a lot of the current algorithms were replaced by algorithms that are more flexible and robust. Deep networks have demonstrated…

计算机视觉与模式识别 · 计算机科学 2019-04-30 Rohit Jena

Denoising is a fundamental challenge in scientific imaging. Deep convolutional neural networks (CNNs) provide the current state of the art in denoising natural images, where they produce impressive results. However, their potential has…

Raman spectroscopy is an important tool in the study of vibrational properties and composition of molecules, peptides and even proteins. Raman spectra can be simulated based on the change of the electronic polarizability with vibrations,…

计算物理 · 物理学 2024-04-30 Ethan Berger , Juha Niemelä , Outi Lampela , André H. Juffer , Hannu-Pekka Komsa

Fluorescence lifetime imaging microscopy (FLIM) systems are limited by their slow processing speed, low signal-to-noise ratio (SNR), and expensive and challenging hardware setups. In this work, we demonstrate applying a denoising…

图像与视频处理 · 电气工程与系统科学 2021-06-09 Varun Mannam , Yide Zhang , Xiaotong Yuan , Takashi Hato , Pierre C. Dagher , Evan L. Nichols , Cody J. Smith , Kenneth W. Dunn , Scott Howard

Ultrasound images are widespread in medical diagnosis for musculoskeletal, cardiac, and obstetrical imaging due to the efficiency and non-invasiveness of the acquisition methodology. However, the acquired images are degraded by acoustic…

图像与视频处理 · 电气工程与系统科学 2023-06-14 Hojat Asgariandehkordi , Sobhan Goudarzi , Adrian Basarab , Hassan Rivaz

Supervised learning-based methods yield robust denoising results, yet they are inherently limited by the need for large-scale clean/noisy paired datasets. The use of unsupervised denoisers, on the other hand, necessitates a more detailed…

图像与视频处理 · 电气工程与系统科学 2021-11-30 Nahyun Kim , Donggon Jang , Sunhyeok Lee , Bomi Kim , Dae-Shik Kim

Hyperspectral stimulated Raman scattering (SRS) microscopy is a label-free technique for biomedical and mineralogical imaging which can suffer from low signal to noise ratios. Here we demonstrate the use of an unsupervised deep learning…

Raman spectroscopy serves as a powerful and reliable tool for analyzing the chemical information of substances. The integration of Raman spectroscopy with deep learning methods enables rapid qualitative and quantitative analysis of…

信号处理 · 电气工程与系统科学 2025-04-24 Pengju Ren , Ri-gui Zhou , Yaochong Li

Capturing images under extremely low-light conditions poses significant challenges for the standard camera pipeline. Images become too dark and too noisy, which makes traditional image enhancement techniques almost impossible to apply. Very…

计算机视觉与模式识别 · 计算机科学 2020-06-19 Ahmet Serdar Karadeniz , Erkut Erdem , Aykut Erdem

Among the plethora of techniques devised to curb the prevalence of noise in medical images, deep learning based approaches have shown the most promise. However, one critical limitation of these deep learning based denoisers is the…

计算机视觉与模式识别 · 计算机科学 2018-12-03 Fahad Shamshad , Muhammad Awais , Muhammad Asim , Zain ul Aabidin Lodhi , Muhammad Umair , Ali Ahmed

While deep neural networks have been shown to perform remarkably well in many machine learning tasks, labeling a large amount of ground truth data for supervised training is usually very costly to scale. Therefore, learning robust…

计算机视觉与模式识别 · 计算机科学 2020-03-31 Jianbo Jiao , Linchao Bao , Yunchao Wei , Shengfeng He , Honghui Shi , Rynson Lau , Thomas S. Huang

Fingerprint image denoising is a very important step in fingerprint identification. to improve the denoising effect of fingerprint image,we have designs a fingerprint denoising algorithm based on deep encoder-decoder network,which encoder…

计算机视觉与模式识别 · 计算机科学 2020-05-05 Weiya Fan

Two-dimensional electronic spectroscopy (2DES) has enabled significant discoveries in both biological and synthetic energy-transducing systems. Although deriving chemical information from 2DES is a complex task, machine learning (ML) offers…

化学物理 · 物理学 2025-03-21 Jonathan D. Schultz , Kelsey A. Parker , Bashir Sbaiti , David N. Beratan

This work proposes a learning-based statistical refinement method for improving the denoising results of a given denoiser without knowing the precise noise distribution or accessing clean images or calibration data. While there are many…

机器学习 · 计算机科学 2026-05-07 Rihuan Ke

Enhancing the visibility in extreme low-light environments is a challenging task. Under nearly lightless condition, existing image denoising methods could easily break down due to significantly low SNR. In this paper, we systematically…

图像与视频处理 · 电气工程与系统科学 2021-08-05 Kaixuan Wei , Ying Fu , Yinqiang Zheng , Jiaolong Yang

Raman spectroscopy provides spectral information related to the specific molecular structures of substances and has been well established as a powerful tool for studying biological tissues and diagnosing diseases. This article reviews…