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With the rapid evolution of Natural Language Processing (NLP), Large Language Models (LLMs) like ChatGPT have emerged as powerful tools capable of transforming various sectors. Their vast knowledge base and dynamic interaction capabilities…

Universal healthcare access is critically needed, especially in resource-limited settings. Large Language Models (LLMs) offer promise for democratizing healthcare with advanced diagnostics, but their reliability requires thorough…

While Large Language Models (LLMs) are being quickly adapted to many domains, including healthcare, their strengths and pitfalls remain under-explored. In our study, we examine the effects of prompt engineering to guide Large Language…

Recent advances in large language models (LLMs) have led to the development of powerful AI chatbots capable of engaging in natural and human-like conversations. However, these chatbots can be potentially harmful, exhibiting manipulative,…

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Large language models (LLMs) have demonstrated capabilities across diverse domains, yet their performance on rare disease diagnosis from narrative medical cases remains underexplored. We introduce a novel dataset of 176 symptom-diagnosis…

In this survey, we address the key challenges in Large Language Models (LLM) research, focusing on the importance of interpretability. Driven by increasing interest from AI and business sectors, we highlight the need for transparency in…

Explainable disease diagnosis, which leverages patient information (e.g., signs and symptoms) and computational models to generate probable diagnoses and reasonings, offers clear clinical values. However, when clinical notes encompass…

Advancements in deep learning have generated a large-scale interest in the development of foundational deep learning models. The development of Large Language Models (LLM) has evolved as a transformative paradigm in conversational tasks,…

In the rapidly evolving landscape of artificial intelligence (AI), generative large language models (LLMs) stand at the forefront, revolutionizing how we interact with our data. However, the computational intensity and memory consumption of…

Genetic programming (GP) has the potential to generate explainable results, especially when used for dimensionality reduction. In this research, we investigate the potential of leveraging eXplainable AI (XAI) and large language models…

Electronic health records (EHRs) house crucial patient data in clinical notes. As these notes grow in volume and complexity, manual extraction becomes challenging. This work introduces a natural language interface using large language…

Large Language Models (LLMs) have demonstrated promise in medical knowledge assessments, yet their practical utility in real-world clinical decision-making remains underexplored. In this study, we evaluated the performance of three…

The shortage of doctors is creating a critical squeeze in access to medical expertise. While conversational Artificial Intelligence (AI) holds promise in addressing this problem, its safe deployment in patient-facing roles remains largely…

Large language models (LLMs) have shown remarkable progress in encoding clinical knowledge and responding to complex medical queries with appropriate clinical reasoning. However, their applicability in subspecialist or complex medical…

Large Language Models (LLMs) like GPT-4, MedPaLM-2, and Med-Gemini achieve performance competitively with human experts across various medical benchmarks. However, they still face challenges in making professional diagnoses akin to…

In recent years, Large Language Models (LLMs) have emerged as a transformative development in artificial intelligence (AI), drawing significant attention from industry and academia. Trained on vast datasets, these sophisticated AI systems…

In recent years, large language models (e.g., Open AI's GPT-4, Meta's LLaMa, Google's PaLM) have become the dominant approach for building AI systems to analyze and generate language online. However, the automated systems that increasingly…

Large Language Models (LLMs) deliver powerful AI capabilities but face deployment challenges due to high resource costs and latency, whereas Small Language Models (SLMs) offer efficiency and deployability at the cost of reduced performance.…

The use of large language model (LLM)-powered chatbots, such as ChatGPT, has become popular across various domains, supporting a range of tasks and processes. However, due to the intrinsic complexity of LLMs, effective prompting is more…