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Generative models such as Generative Adversarial Networks (GANs) and Variational Auto-Encoders (VAEs) are widely utilized to model the generative process of user interactions. However, these generative models suffer from intrinsic…

信息检索 · 计算机科学 2025-06-26 Wenjie Wang , Yiyan Xu , Fuli Feng , Xinyu Lin , Xiangnan He , Tat-Seng Chua

Graph is a prevalent discrete data structure, whose generation has wide applications such as drug discovery and circuit design. Diffusion generative models, as an emerging research focus, have been applied to graph generation tasks.…

机器学习 · 计算机科学 2024-11-05 Zhe Xu , Ruizhong Qiu , Yuzhong Chen , Huiyuan Chen , Xiran Fan , Menghai Pan , Zhichen Zeng , Mahashweta Das , Hanghang Tong

Near the beginning of the century, Wright and Fisher devised an elegant, mathematically tractable model of gene reproduction and replacement that laid the foundation for contemporary population genetics. The Wright-Fisher model and its…

概率论 · 数学 2013-12-23 Todd L. Parsons

Demographic models built from genetic data play important roles in illuminating prehistorical events and serving as null models in genome scans for selection. We introduce an inference method based on the joint frequency spectrum of genetic…

种群与进化 · 定量生物学 2010-05-10 Ryan N. Gutenkunst , Ryan D. Hernandez , Scott H. Williamson , Carlos D. Bustamante

This paper delves into the study of 3D point cloud reconstruction from a single image. Our objective is to develop the Consistency Diffusion Model, exploring synergistic 2D and 3D priors in the Bayesian framework to ensure superior…

计算机视觉与模式识别 · 计算机科学 2025-02-03 Chenru Jiang , Chengrui Zhang , Xi Yang , Jie Sun , Yifei Zhang , Bin Dong , Kaizhu Huang

Diffusion probabilistic models have quickly become a major approach for generative modeling of images, 3D geometry, video and other domains. However, to adapt diffusion generative modeling to these domains the denoising network needs to be…

计算机视觉与模式识别 · 计算机科学 2023-03-02 Peiye Zhuang , Samira Abnar , Jiatao Gu , Alex Schwing , Joshua M. Susskind , Miguel Ángel Bautista

The goal of this paper is to develop a theory of graphon-valued stochastic processes, and to construct and analyse a natural class of such processes arising from population genetics. We consider finite populations where individuals change…

概率论 · 数学 2019-08-20 Siva Athreya , Frank den Hollander , Adrian Röllin

Starting from the dynamical system model capturing the splitting-differentiation process of populations, we extend this notion to show how the speciation mechanism from a single species leads to the consideration of several well known…

偏微分方程分析 · 数学 2024-01-29 Gonzalo Galiano , Virginia Selgas

We propose TaxaDiffusion, a taxonomy-informed training framework for diffusion models to generate fine-grained animal images with high morphological and identity accuracy. Unlike standard approaches that treat each species as an independent…

计算机视觉与模式识别 · 计算机科学 2025-06-27 Amin Karimi Monsefi , Mridul Khurana , Rajiv Ramnath , Anuj Karpatne , Wei-Lun Chao , Cheng Zhang

The transition distribution of a sample taken from a Wright-Fisher diffusion with general small mutation rates is found using a coalescent approach. The approximation is equivalent to having at most one mutation in the coalescent tree of…

种群与进化 · 定量生物学 2019-09-12 Conrad J. Burden , Robert C. Griffiths

Diffusions are a successful technique to sample from high-dimensional distributions. The target distribution can be either explicitly given or learnt from a collection of samples. They implement a diffusion process whose endpoint is a…

机器学习 · 计算机科学 2025-09-03 Andrea Montanari

We consider two processes that have been used to study gene duplication, Watterson's [Genetics 105 (1983) 745--766] double recessive null model and Lynch and Force's [Genetics 154 (2000) 459--473] subfunctionalization model. Though the…

概率论 · 数学 2009-03-02 Rick Durrett , Lea Popovic

Characterizing time-evolution of allele frequencies in a population is a fundamental problem in population genetics. In the Wright-Fisher diffusion, such dynamics is captured by the transition density function, which satisfies well-known…

概率论 · 数学 2013-08-06 Matthias Steinrücken , Y. X. Rachel Wang , Yun S. Song

In real-life conversations, the content is diverse, and there exists the one-to-many problem that requires diverse generation. Previous studies attempted to introduce discrete or Gaussian-based continuous latent variables to address the…

计算与语言 · 计算机科学 2024-04-11 Jianxiang Xiang , Zhenhua Liu , Haodong Liu , Yin Bai , Jia Cheng , Wenliang Chen

Diffusion models have emerged as powerful generative frameworks by progressively adding noise to data through a forward process and then reversing this process to generate realistic samples. While these models have achieved strong…

机器学习 · 计算机科学 2025-03-04 Xingzhuo Guo , Yu Zhang , Baixu Chen , Haoran Xu , Jianmin Wang , Mingsheng Long

Diffusion models that are based on iterative denoising have been recently proposed and leveraged in various generation tasks like image generation. Whereas, as a way inherently built for continuous data, existing diffusion models still have…

计算与语言 · 计算机科学 2023-04-11 Jiaao Chen , Aston Zhang , Mu Li , Alex Smola , Diyi Yang

We present a novel simulation-free framework for training continuous-time diffusion processes over very general objective functions. Existing methods typically involve either prescribing the optimal diffusion process -- which only works for…

机器学习 · 计算机科学 2025-06-24 Mengjian Hua , Eric Vanden-Eijnden , Ricky T. Q. Chen

For the sake of computational efficiency and for theoretical purposes, in mathematical modelling, the Dirac Delta distributions are often utilized as a replacement for cells or vesicles, since the size of cells or vesicles is much smaller…

数值分析 · 数学 2023-11-09 Qiyao Peng , Sander C. Hille

Kernel methods on discrete domains have shown great promise for many challenging data types, for instance, biological sequence data and molecular structure data. Scalable kernel methods like Support Vector Machines may offer good predictive…

机器学习 · 统计学 2021-05-27 Vincent Fortuin , Gideon Dresdner , Heiko Strathmann , Gunnar Rätsch

Mathematical models of biological populations commonly use discrete structure classes to capture trait variation among individuals (e.g. age, size, phenotype, intracellular state). Upscaling these discrete models into continuum descriptions…

种群与进化 · 定量生物学 2026-03-18 Eleonora Agostinelli , Keith L. Chambers , Helen M. Byrne , Mohit P. Dalwadi