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Single-cell sequencing has a significant role to explore biological processes such as embryonic development, cancer evolution, and cell differentiation. These biological properties can be presented by a two-dimensional scatter plot.…

基因组学 · 定量生物学 2021-10-19 Ziyi Liu , Minghui Liao , Fulin luo , Bo Du

Data are not only ubiquitous in society, but are increasingly complex both in size and dimensionality. Dimension reduction offers researchers and scholars the ability to make such complex, high dimensional data spaces simpler and more…

机器学习 · 计算机科学 2021-03-15 Philip D. Waggoner

Support Vector Data Description (SVDD) provides a useful approach to construct a description of multivariate data for single-class classification and outlier detection with various practical applications. Gaussian kernel used in SVDD…

机器学习 · 计算机科学 2018-11-02 Sergiy Peredriy , Deovrat Kakde , Arin Chaudhuri

The Gaussian kernel plays a central role in machine learning, uncertainty quantification and scattered data approximation, but has received relatively little attention from a numerical analysis standpoint. The basic problem of finding an…

数值分析 · 数学 2021-04-02 Toni Karvonen , Chris J. Oates , Mark Girolami

This work is concerned with the continuum limit of a graph-based data visualization technique called the t-Distributed Stochastic Neighbor Embedding (t-SNE), which is widely used for visualizing data in a variety of applications, but is…

机器学习 · 统计学 2026-04-15 Jeff Calder , Zhonggan Huang , Ryan Murray , Adam Pickarski

Single-cell RNA-seq datasets are growing in size and complexity, enabling the study of cellular composition changes in various biological/clinical contexts. Scalable dimensionality reduction techniques are in need to disentangle biological…

This paper develops an in-depth treatment concerning the problem of approximating the Gaussian smoothing and Gaussian derivative computations in scale-space theory for application on discrete data. With close connections to previous…

计算机视觉与模式识别 · 计算机科学 2024-06-25 Tony Lindeberg

Scientific datasets often have hierarchical structure: for example, in surveys, individual participants (samples) might be grouped at a higher level (units) such as their geographical region. In these settings, the interest is often in…

机器学习 · 计算机科学 2024-06-06 Fynn Bachmann , Philipp Hennig , Dmitry Kobak

Convolutional neural networks (CNNs) are essential tools for computer vision tasks, but they lack traditionally desired properties of extracted features that could further improve model performance, e.g., rotational equivariance. Such…

计算机视觉与模式识别 · 计算机科学 2025-01-17 Yuexi Du , Jiazhen Zhang , Tal Zeevi , Nicha C. Dvornek , John A. Onofrey

Gaussian processes offers a convenient way to perform nonparametric reconstructions of observational data assuming only a kernel which describes the covariance between neighbouring points in a data set. We approach the ambiguity in the…

宇宙学与河外天体物理 · 物理学 2021-08-17 Reginald Christian Bernardo , Jackson Levi Said

Stochastic Neighbor Embedding (SNE) algorithms like UMAP and tSNE often produce visualizations that do not preserve the geometry of noisy and high dimensional data. In particular, they can spuriously separate connected components of the…

机器学习 · 计算机科学 2025-09-05 Tristan Luca Saidi , Abigail Hickok , Bastian Rieck , Andrew J. Blumberg

Kernel methods are powerful tools in machine learning. They have to be computationally efficient. In this paper, we present a novel Geometric-based approach to compute efficiently the string subsequence kernel (SSK). Our main idea is that…

机器学习 · 计算机科学 2015-03-02 Slimane Bellaouar , Hadda Cherroun , Djelloul Ziadi

Single-cell sequencing is revolutionizing biology by enabling detailed investigations of cell-state transitions. Many biological processes unfold along continuous trajectories, yet it remains challenging to extract smooth, low-dimensional…

机器学习 · 统计学 2025-06-30 Rong Ma , Xi Li , Jingyuan Hu , Bin Yu

Large photometric surveys provide a rich source of observations of quiescent galaxies, including a surprisingly large population at z>1. However, identifying large, but clean, samples of quiescent galaxies has proven difficult because of…

Group convolutional neural networks (G-CNNs) have been shown to increase parameter efficiency and model accuracy by incorporating geometric inductive biases. In this work, we investigate the properties of representations learned by regular…

计算机视觉与模式识别 · 计算机科学 2022-04-05 David M. Knigge , David W. Romero , Erik J. Bekkers

Self-attention (SA) based models have recently achieved significant performance improvements in hybrid and end-to-end automatic speech recognition (ASR) systems owing to their flexible context modeling capability. However, it is also known…

音频与语音处理 · 电气工程与系统科学 2021-02-19 Yosuke Kashiwagi , Emiru Tsunoo , Shinji Watanabe

t-distributed Stochastic Neighborhood Embedding (t-SNE), a clustering and visualization method proposed by van der Maaten & Hinton in 2008, has rapidly become a standard tool in a number of natural sciences. Despite its overwhelming…

机器学习 · 计算机科学 2017-06-09 George C. Linderman , Stefan Steinerberger

We present a Gaussian kernel loss function and training algorithm for convolutional neural networks that can be directly applied to both distance metric learning and image classification problems. Our method treats all training features…

计算机视觉与模式识别 · 计算机科学 2018-07-03 Benjamin J. Meyer , Ben Harwood , Tom Drummond

A fundamental step in many data-analysis techniques is the construction of an affinity matrix describing similarities between data points. When the data points reside in Euclidean space, a widespread approach is to from an affinity matrix…

机器学习 · 统计学 2021-01-27 Boris Landa , Ronald R. Coifman , Yuval Kluger

Stochastic Neighbor Embedding (SNE) methods minimize the divergence between the similarity matrix of a high-dimensional data set and its counterpart from a low-dimensional embedding, leading to widely applied tools for data visualization.…

机器学习 · 计算机科学 2018-09-13 Yao Lu , Jukka Corander , Zhirong Yang