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相关论文: A Scientific Reasoning Model for Organic Synthesis…

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We propose cognitive prompting as a novel approach to guide problem-solving in large language models (LLMs) through structured, human-like cognitive operations, such as goal clarification, decomposition, filtering, abstraction, and pattern…

计算与语言 · 计算机科学 2024-12-03 Oliver Kramer , Jill Baumann

As large language models (LLMs) witness increasing deployment in complex, high-stakes decision-making scenarios, it becomes imperative to ground their reasoning in causality rather than spurious correlations. However, strong performance on…

人工智能 · 计算机科学 2026-02-24 Yuzhe Wang , Yaochen Zhu , Jundong Li

Unlocking deep and interpretable biological reasoning from complex genomic data remains a major AI challenge limiting scientific progress. While current DNA foundation models excel at representing sequences, they struggle with multi-step…

Numerical reasoning is an essential ability for NLP systems to handle numeric information. Recent research indicates that fine-tuning a small-scale model to learn generating reasoning processes alongside answers can significantly enhance…

计算与语言 · 计算机科学 2024-02-19 Dingzirui Wang , Longxu Dou , Xuanliang Zhang , Qingfu Zhu , Wanxiang Che

We propose a novel Chain Guided Retriever-reader ({\tt CGR}) framework to model the reasoning chain for multi-hop Science Question Answering. Our framework is capable of performing explainable reasoning without the need of any…

计算与语言 · 计算机科学 2021-09-08 Weiwen Xu , Yang Deng , Huihui Zhang , Deng Cai , Wai Lam

Effective code generation with language models hinges on two critical factors: accurately understanding the intent of the prompt and generating code that applies algorithmic reasoning to produce correct solutions capable of passing diverse…

人工智能 · 计算机科学 2025-10-21 Amir Jalilifard , Anderson de Rezende Rocha , Marcos Medeiros Raimundo

Generating novel and creative scientific hypotheses is a cornerstone in achieving Artificial General Intelligence. Large language and reasoning models have the potential to aid in the systematic creation, selection, and validation of…

计算与语言 · 计算机科学 2025-04-18 Charles O'Neill , Tirthankar Ghosal , Roberta Răileanu , Mike Walmsley , Thang Bui , Kevin Schawinski , Ioana Ciucă

Medical tasks such as diagnosis and treatment planning require precise and complex reasoning, particularly in life-critical domains. Unlike mathematical reasoning, medical reasoning demands meticulous, verifiable thought processes to ensure…

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

计算与语言 · 计算机科学 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

Large Reasoning Models (LRMs) exhibit remarkable reasoning abilities but rely primarily on parametric knowledge, limiting factual accuracy. While recent works equip reinforcement learning (RL)-based LRMs with retrieval capabilities, they…

计算与语言 · 计算机科学 2025-05-20 Zhicheng Lee , Shulin Cao , Jinxin Liu , Jiajie Zhang , Weichuan Liu , Xiaoyin Che , Lei Hou , Juanzi Li

Large language models (LLMs) are beginning to reshape how chemists plan and run reactions in organic synthesis. Trained on millions of reported transformations, these text-based models can propose synthetic routes, forecast reaction…

人工智能 · 计算机科学 2025-08-08 Kartar Kumar Lohana Tharwani , Rajesh Kumar , Sumita , Numan Ahmed , Yong Tang

Retrieval-augmented generation (RAG) has emerged as a powerful framework for enhancing large language models (LLMs) with external knowledge, particularly in scientific domains that demand specialized and dynamic information. Despite its…

计算与语言 · 计算机科学 2026-02-17 Xianrui Zhong , Bowen Jin , Siru Ouyang , Yanzhen Shen , Qiao Jin , Yin Fang , Zhiyong Lu , Jiawei Han

Emerging reasoning models hold promise for automating scientific discovery. However, their training is hindered by a critical supervision gap: experimental outcomes are abundant, whereas intermediate reasoning steps are rarely documented at…

生物大分子 · 定量生物学 2026-03-24 Zequn Liu , Kehan Wu , Shufang Xie , Zekun Guo , Wei Zhang , Tao Qin , Renhe Liu , Yingce Xia

Retrieval-augmented generation (RAG) systems have advanced large language models (LLMs) in complex deep search scenarios requiring multi-step reasoning and iterative information retrieval. However, existing approaches face critical…

We investigate how to teach large language models (LLMs) to perform scientific reasoning by leveraging expert discussions as a learning signal. Focusing on the genomics domain, we develop an automated pipeline to extract trainable data and…

人工智能 · 计算机科学 2025-06-04 Ming Yin , Yuanhao Qu , Ling Yang , Le Cong , Mengdi Wang

Large Language Models (LLMs) have shown promising performance on diverse medical benchmarks, highlighting their potential in supporting real-world clinical tasks. Retrieval-Augmented Generation (RAG) has emerged as a key approach for…

计算与语言 · 计算机科学 2025-09-30 Kaishuai Xu , Wenjun Hou , Yi Cheng , Wenjie Li

The evolution of Large Language Models (LLMs) from static instruction-followers to autonomous agents necessitates operating within complex, stateful environments to achieve precise state-transition objectives. However, this paradigm is…

The realization of autonomous scientific experimentation is currently limited by LLMs' struggle to grasp the strict procedural logic and accuracy required by biological protocols. To address this fundamental challenge, we present…

计算与语言 · 计算机科学 2026-01-22 Yuyang Liu , Liuzhenghao Lv , Xiancheng Zhang , Jingya Wang Li Yuan , Yonghong Tian

Program synthesis is the generation of a program from a specification. Correct synthesis is difficult, and methods that provide formal guarantees suffer from scalability issues. On the other hand, neural networks are able to generate…

计算机科学中的逻辑 · 计算机科学 2020-01-28 Elizabeth Polgreen , Ralph Abboud , Daniel Kroening

Process-Level Reward Models (PRMs) are essential for guiding complex reasoning in large language models, yet existing PRM benchmarks cover only general domains such as mathematics, failing to address medical reasoning -- which is uniquely…

计算与语言 · 计算机科学 2026-04-21 Lingyan Wu , Xiang Zheng , Weiqi Zhai , Wei Wang , Xuan Ren , Zifan Zhang , Hu Wei , Bing Zhao