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相关论文: Advances in Ontology--Based Mining of Adverse Drug…

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Monitoring the biomedical literature for cases of Adverse Drug Reactions (ADRs) is a critically important and time consuming task in pharmacovigilance. The development of computer assisted approaches to aid this process in different forms…

计算与语言 · 计算机科学 2018-04-25 Diego Saldana Miranda

Adverse drug reactions / events (ADR/ADE) have a major impact on patient health and health care costs. Detecting ADR's as early as possible and sharing them with regulators, pharma companies, and healthcare providers can prevent morbidity…

计算与语言 · 计算机科学 2022-01-07 Hasham Ul Haq , Veysel Kocaman , David Talby

Automatic monitoring of adverse drug events (ADEs) or reactions (ADRs) is currently receiving significant attention from the biomedical community. In recent years, user-generated data on social media has become a valuable resource for this…

计算与语言 · 计算机科学 2023-11-21 Ilseyar Alimova , Elena Tutubalina

Spontaneous reporting system databases are key resources for post-marketing surveillance, providing real-world evidence (RWE) on the adverse events (AEs) of regulated drugs or other medical products. Various statistical methods have been…

统计方法学 · 统计学 2026-03-24 Xin-Wei Huang , Saptarshi Chakraborty

Adverse Drug Event (ADE) extraction models can rapidly examine large collections of social media texts, detecting mentions of drug-related adverse reactions and trigger medical investigations. However, despite the recent advances in NLP, it…

计算与语言 · 计算机科学 2021-09-27 Simone Scaboro , Beatrice Portelli , Emmanuele Chersoni , Enrico Santus , Giuseppe Serra

Adverse drug events (ADEs) are an important aspect of drug safety. Various texts such as biomedical literature, drug reviews, and user posts on social media and medical forums contain a wealth of information about ADEs. Recent studies have…

计算与语言 · 计算机科学 2024-05-21 Shaoxiong Ji , Ya Gao , Pekka Marttinen

Adverse drug reactions (ADRs) are unwanted or harmful effects experienced after the administration of a certain drug or a combination of drugs, presenting a challenge for drug development and drug administration. In this paper, we present a…

计算与语言 · 计算机科学 2019-05-29 Maksim Belousov , Nikola Milosevic , William Dixon , Goran Nenadic

Adverse drug events (ADEs) are unexpected incidents caused by the administration of a drug or medication. To identify and extract these events, we require information about not just the drug itself but attributes describing the drug (e.g.,…

计算与语言 · 计算机科学 2021-04-23 Darshini Mahendran , Bridget T. McInnes

Vaccine safety is a concerning problem of the public, and many signal detecting methods have been developed to identify relative risks between vaccines and adverse events (AEs). Those methods usually focus on individual AEs, where the…

应用统计 · 统计学 2020-10-26 Bangyao Zhao , Lili Zhao

Adverse Drug Reaction (ADR) is a significant public health concern world-wide. Numerous graph-based methods have been applied to biomedical graphs for predicting ADRs in pre-marketing phases. ADR detection in post-market surveillance is no…

机器学习 · 计算机科学 2020-04-02 Heeyoung Kwak , Minwoo Lee , Seunghyun Yoon , Jooyoung Chang , Sangmin Park , Kyomin Jung

We present an algorithm based on multi-layer transformers for identifying Adverse Drug Reactions (ADR) in social media data. Our model relies on the properties of the problem and the characteristics of contextual word embeddings to extract…

计算与语言 · 计算机科学 2021-05-25 Payam Karisani , Jinho D. Choi , Li Xiong

Adverse drug events (ADE) are prevalent and costly. Clinical trials are constrained in their ability to identify potential ADEs, motivating the development of spontaneous reporting systems for post-market surveillance. Statistical methods…

计算与语言 · 计算机科学 2020-08-11 Xiruo Ding , Trevor Cohen

Adverse reaction caused by drugs is a potentially dangerous problem which may lead to mortality and morbidity in patients. Adverse Drug Event (ADE) extraction is a significant problem in biomedical research. We model ADE extraction as a…

计算与语言 · 计算机科学 2018-01-03 Suriyadeepan Ramamoorthy , Selvakumar Murugan

With the advancements in Artificial intelligence (AI) and the accumulation of healthrelated big data, it has become increasingly feasible and commonplace to leverage machine learning technologies to analyze clinical and omics metadata to…

基因组学 · 定量生物学 2022-04-14 Attayeb Mohsen , Lokesh P. Tripathi , Kenji Mizuguchi

Adverse drug reaction (ADR) prediction plays a crucial role in both health care and drug discovery for reducing patient mortality and enhancing drug safety. Recently, many studies have been devoted to effectively predict the drug-ADRs…

信息检索 · 计算机科学 2023-08-08 Haoxuan Li , Taojun Hu , Zetong Xiong , Chunyuan Zheng , Fuli Feng , Xiangnan He , Xiao-Hua Zhou

Social media is an useful platform to share health-related information due to its vast reach. This makes it a good candidate for public-health monitoring tasks, specifically for pharmacovigilance. We study the problem of extraction of…

信息检索 · 计算机科学 2017-09-07 Shashank Gupta , Sachin Pawar , Nitin Ramrakhiyani , Girish Palshikar , Vasudeva Varma

Adverse drug reactions (ADRs) are big concern for public health. ADRs are one of most common causes to withdraw some drugs from markets. Now two major methods for detecting ADRs are spontaneous reporting system (SRS), and prescription event…

计算工程、金融与科学 · 计算机科学 2013-09-02 Yihui Liu , Uwe Aickelin

Adverse drug interactions are a critical concern in pharmacovigilance, as both clinical trials and spontaneous reporting systems often lack the breadth to detect complex drug interactions. This study introduces a computational framework for…

应用统计 · 统计学 2025-04-02 Jules Bangard , Einar Holsbø , Kristian Svendsen , Vittorio Perduca , Etienne Birmelé

Adverse drug reactions (ADRs) are one of the leading causes of mortality in health care. Current ADR surveillance systems are often associated with a substantial time lag before such events are officially published. On the other hand,…

信息检索 · 计算机科学 2018-02-15 Shashank Gupta , Manish Gupta , Vasudeva Varma , Sachin Pawar , Nitin Ramrakhiyani , Girish K. Palshikar

Adverse drug events (ADEs) are a major safety issue in clinical trials. Thus, predicting ADEs is key to developing safer medications and enhancing patient outcomes. To support this effort, we introduce CT-ADE, a dataset for multilabel ADE…

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