相关论文: Active Force Dynamics in Red Blood Cells Under Non…
Red blood cells possess unique biomechanical ability to squeeze through capillaries smaller than their size to enable gas and ion exchange. A key signature of their active biomechanics is the out-of-equilibrium fluctuation of the plasma…
The reversible aggregation of red blood cells (RBCs) is a process of erythrocytes clumping that strongly influences the rheological properties of blood. The adhesion of RBCs has been studied extensively in the frame of cell-to-cell…
Red Blood Cells (RBCs) are the simplest cell types with complex dynamical and viscoelastic phenomenology. While the mechanical rigidity and the flickering noise of RBCs have been extensively investigated, an accurate determination of the…
The dynamics of red blood cells (RBCs) in simple shear flow was studied using a theoretical approach based on three variables: a shape parameter, the inclination angle $\theta$, and phase angle $\phi$ of the membrane rotation. At high shear…
Computational Fluid Dynamics (CFD) is currently used to design and improve the hydraulic properties of biomedical devices, wherein the large scale blood circulation needs to be simulated by accounting for the mechanical response of red…
The dynamics of red blood cells (RBCs) in oscillatory shear flow was studied using differential equations of three variables: a shape parameter, the inclination angle $\theta$, and phase angle $\phi$ of the membrane rotation. In steady…
The red blood cell (RBC) membrane is composed of a lipid bilayer and a cytoskeleton interconnected by protein junction complexes, allowing for potential sliding between the lipid bilayer and the cytoskeleton. Despite this biological…
We measure the dynamical mechanical properties of human red blood cells. Single cell response is measured with optical tweezers. We investigate both the stress relaxation following a fast deformation, and the effect of varying the strain…
We present a rigorous procedure to derive coarse-grained red blood cell (RBC) models, which lead to accurate mechanical properties of realistic RBCs. Based on a semi-analytic theory linear and non-linear elastic properties of the RBC…
We investigate the physics of an optically-driven micromotor of biological origin. A single, live red blood cell, when placed in an optical trap folds into a rod-like shape. If the trapping laser beam is circularly polarized, the folded RBC…
We consider the motion of red blood cells and other non-spherical microcapsules dilutely suspended in a simple shear flow. Our analysis indicates that depending on the viscosity, membrane elasticity, geometry and shear rate, the particle…
We use mesoscale numerical simulations to investigate the unsteady dynamics of a single red blood cell (RBC) subjected to an external mechanical load. We carry out a detailed comparison between the {\it loading} (L) dynamics, following the…
The study of vesicles under flow, a model system for red blood cells (RBCs), is an essential step in understanding various intricate dynamics exhibited by RBCs in vivo and in vitro. Quantitative 3D analyses of vesicles under flow are…
This study investigates the dynamics of red blood cells (RBCs) under the influence of evanescent waves generated by total internal reflection (TIR). Using a 1064 nm laser system and a dual-chamber prism setup, we quantified the mobility of…
We investigate the dynamics of the Red Blood Cell (RBC) in microfluidic channels under oscillatory flows. The simulations employ a hybrid continuum-particle approach, in which the cell membrane and cytosol fluid are modeled using…
We reveal that under moderate shear stress (of the order of 0.1 Pa) red blood cells present an oscillation of their inclination (swinging) superimposed to the long-observed steady tanktreading (TT) motion. A model based on a fluid ellipsoid…
The flow dynamics of red blood cells in vivo in blood capillaries and in vitro in microfluidic channels is complex. Cells can obtain differnet shapes such as discoid, parachute, slipper-like shapes and various intermediate states depending…
Optical tweezers are a technique in which microscopic-sized particles, including living cells and bacteria, can be non-intrusively trapped with high accuracy solely using focused light. The technique has therefore become a powerful tool in…
Normal thermal fluctuations of the cell membrane have been studied extensively using high resolution microscopy and focused light, particularly at the peripheral regions of a cell. We use a single probe particle attached non-specifically to…
Active contributions to fluctuations are a direct consequence of metabolic energy consumption in living cells. Such metabolic processes continuously create active forces, which deform the membrane to control motility, proliferation as well…