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Motivated by the gene co-expression pattern analysis, we propose a novel sample quantile-based contingency (squac) statistic to infer quantile associations conditioning on covariates. It features enhanced flexibility in handling variables…

统计方法学 · 统计学 2018-08-27 Jichun Xie , Ruosha Li

The recently proposed fixed-X knockoff is a powerful variable selection procedure that controls the false discovery rate (FDR) in any finite-sample setting, yet its theoretical insights are difficult to show beyond Gaussian linear models.…

统计方法学 · 统计学 2023-11-28 Han Su , Panxu Yuan , Qingyang Sun , Mengxi Yi , Gaorong Li

In modern scientific research, the objective is often to identify which variables are associated with an outcome among a large class of potential predictors. This goal can be achieved by selecting variables in a manner that controls the the…

统计方法学 · 统计学 2023-10-10 Yushu Shi , Michael Martens

The false discovery rate (FDR)---the expected fraction of spurious discoveries among all the discoveries---provides a popular statistical assessment of the reproducibility of scientific studies in various disciplines. In this work, we…

机器学习 · 统计学 2015-11-10 Weijie Su , Junyang Qian , Linxi Liu

The Multi-Kink Quantile Regression (MKQR) model is an important tool for analyzing data with heterogeneous conditional distributions, especially when quantiles of response variable are of interest, due to its robustness to outliers and…

统计方法学 · 统计学 2020-06-16 Wei Zhong , Chuang Wan , Wenyang Zhang

Instance segmentation plays a pivotal role in medical image analysis by enabling precise localization and delineation of lesions, tumors, and anatomical structures. Although deep learning models such as Mask R-CNN and BlendMask have…

计算机视觉与模式识别 · 计算机科学 2025-04-29 Mengxia Dai , Wenqian Luo , Tianyang Li

Conformalized Quantile Regression (CQR) is a recently proposed method for constructing prediction intervals for a response $Y$ given covariates $X$, without making distributional assumptions. However, existing constructions of CQR can be…

统计方法学 · 统计学 2024-05-16 Raphael Rossellini , Rina Foygel Barber , Rebecca Willett

Algorithms that ensure reproducible findings from large-scale, high-dimensional data are pivotal in numerous signal processing applications. In recent years, multivariate false discovery rate (FDR) controlling methods have emerged,…

统计方法学 · 统计学 2024-01-31 Jasin Machkour , Michael Muma , Daniel P. Palomar

Controlling the false discovery rate (FDR) in high-dimensional variable selection requires balancing rigorous error control with statistical power. Existing methods with provable guarantees are often overly conservative, creating a…

统计方法学 · 统计学 2026-02-06 Arnau Vilella , Jasin Machkour , Michael Muma , Daniel P. Palomar

Stability and reproducibility are essential considerations in various applications of statistical methods. False Discovery Rate (FDR) control methods are able to control false signals in scientific discoveries. However, many FDR control…

统计方法学 · 统计学 2025-12-22 Jiajun Sun , Zhanrui Cai , Wei Zhong

False discovery rate (FDR) control methods are essential for voxel-wise multiple testing in neuroimaging data analysis, where hundreds of thousands or even millions of tests are conducted to detect brain regions associated with…

机器学习 · 统计学 2025-05-30 Taehyo Kim , Qiran Jia , Mony J. de Leon , Hai Shu

Recently, the scheme of model-X knockoffs was proposed as a promising solution to address controlled feature selection under high-dimensional finite-sample settings. However, the procedure of model-X knockoffs depends heavily on the…

统计方法学 · 统计学 2022-03-10 Xuebin Zhao , Hong Chen , Yingjie Wang , Weifu Li , Tieliang Gong , Yulong Wang , Feng Zheng

The reduced-rank regression model is a popular model to deal with multivariate response and multiple predictors, and is widely used in biology, chemometrics, econometrics, engineering, and other fields. In the reduced-rank regression…

统计方法学 · 统计学 2022-07-05 Canhong Wen , Qin Wang , Yuan Jiang

The random feature (RF) approach is a well-established and efficient tool for scalable kernel methods, but existing literature has primarily focused on kernel ridge regression with random features (KRR-RF), which has limitations in handling…

机器学习 · 统计学 2025-03-18 Caixing Wang , Xingdong Feng

We introduce DiffKnock, a diffusion-based knockoff framework for high-dimensional feature selection with finite-sample false discovery rate (FDR) control. DiffKnock addresses two key limitations of existing knockoff methods: preserving…

统计方法学 · 统计学 2025-10-03 Heng Ge , Qing Lu

Model-X knockoff has garnered significant attention among various feature selection methods due to its guarantees for controlling the false discovery rate (FDR). Since its introduction in parametric design, knockoff techniques have evolved…

机器学习 · 计算机科学 2024-11-11 Hongyu Shen , Yici Yan , Zhizhen Zhao

Motivation: Detecting local correlations in expression between neighbor genes along the genome has proved to be an effective strategy to identify possible causes of transcriptional deregulation in cancer. It has been successfully used to…

Multiple comparisons in hypothesis testing often encounter structural constraints in various applications. For instance, in structural Magnetic Resonance Imaging for Alzheimer's Disease, the focus extends beyond examining atrophic brain…

统计方法学 · 统计学 2023-11-08 Yang Cao , Xinwei Sun , Yuan Yao

False discovery rate (FDR) controlling procedures provide important statistical guarantees for the replicability in signal identification based on multiple hypotheses testing. In many fields of study, FDR controlling procedures are used in…

统计方法学 · 统计学 2022-10-04 Ran Dai , Cheng Zheng

Identification of genes that initiate cell anomalies and cause cancer in humans is among the important fields in the oncology researches. The mutation and development of anomalies in these genes are then transferred to other genes in the…

分子网络 · 定量生物学 2023-03-03 Mostafa Akhavan Safar , Babak Teimourpour , Abbas Nozari-Dalini
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