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In 2015 the US federal government sponsored a dengue forecasting competition using historical case data from Iquitos, Peru and San Juan, Puerto Rico. Competitors were evaluated on several aspects of out-of-sample forecasts including the…
Longitudinal and time-to-event data are often analyzed in biomarker research to study the association between the longitudinal biomarker measurements and the event-time outcome, in which the longitudinal information contributes to the…
Modeling response surfaces with abrupt jumps and discontinuities remains a major challenge across scientific and engineering domains. Although Gaussian process models excel at capturing smooth nonlinear relationships, their stationarity…
Epilepsy is a chronic neurological disorder that affects a significant portion of the human population and imposes serious risks in the daily life of patients. Despite advances in machine learning and IoT, small, nonstigmatizing wearable…
The development of robust generative models for highly varied non-stationary time series data is a complex yet important problem. Traditional models for time series data prediction, such as Long Short-Term Memory (LSTM), are inefficient and…
High-frequency physiological waveform modality offers deep, real-time insights into patient status. Recently, physiological foundation models based on Photoplethysmography (PPG), such as PPG-GPT, have been shown to predict critical events,…
Gaussian Processes (GPs) are widely used for regression and system identification due to their flexibility and ability to quantify uncertainty. However, their computational complexity limits their applicability to small datasets. Moreover…
Longitudinal data are important in numerous fields, such as healthcare, sociology and seismology, but real-world datasets present notable challenges for practitioners because they can be high-dimensional, contain structured missingness…
Objective: In this paper, we develop a personalized real-time risk scoring algorithm that provides timely and granular assessments for the clinical acuity of ward patients based on their (temporal) lab tests and vital signs; the proposed…
In several countries, including Italy, a prominent approach to population health surveillance involves conducting repeated cross-sectional surveys at short intervals of time. These surveys gather information on the health status of…
With the increased awareness of situations of mental crisis and their societal impact, online services providing emergency support are becoming commonplace in many countries. Computational models, trained on discussions between help-seekers…
Even when aggregate accuracy is high, state-of-the-art NLP models often fail systematically on specific subgroups of data, resulting in unfair outcomes and eroding user trust. Additional data collection may not help in addressing these…
In many biomedical applications, outcome is measured as a ``time-to-event'' (eg. disease progression or death). To assess the connection between features of a patient and this outcome, it is common to assume a proportional hazards model,…
We propose a similarity measure for sparsely sampled time course data in the form of a log-likelihood ratio of Gaussian processes (GP). The proposed GP similarity is similar to a Bayes factor and provides enhanced robustness to noise in…
Clinical time series data from electronic health records and medical registries offer unprecedented opportunities to understand patient trajectories and inform medical decision-making. However, leveraging such data presents significant…
Survival analysis provides a well-established framework for modeling time-to-event data, with hazard and survival functions formally defined as population-level quantities. In applied work, however, these quantities are often interpreted as…
Type 2 diabetes case reports describe complex clinical courses, but their timelines are often expressed in language that is difficult to reuse in longitudinal modeling. To address this gap, we developed a textual time-series corpus of 136…
A probabilistic expert system emulates the decision-making ability of a human expert through a directional graphical model. The first step in building such systems is to understand data generation mechanism. To this end, one may try to…
Latent Gaussian models (LGMs) are perhaps the most commonly used class of models in statistical applications. Nevertheless, in areas ranging from longitudinal studies in biostatistics to geostatistics, it is easy to find datasets that…
Heteroscedastic regression considering the varying noises among observations has many applications in the fields like machine learning and statistics. Here we focus on the heteroscedastic Gaussian process (HGP) regression which integrates…