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Alzheimer's Disease (AD) is a progressive neurodegenerative disorder that poses significant diagnostic challenges due to its complex etiology. Graph Convolutional Networks (GCNs) have shown promise in modeling brain connectivity for AD…

计算机视觉与模式识别 · 计算机科学 2025-04-02 Tianqi Ding , Dawei Xiang , Keith E Schubert , Liang Dong

Clinical studies reveal disruptions in brain structural connectivity (SC) and functional connectivity (FC) in neuropsychiatric disorders such as schizophrenia (SZ). Traditional approaches might rely solely on SC due to limited functional…

图像与视频处理 · 电气工程与系统科学 2026-01-27 Badhan Mazumder , Ayush Kanyal , Lei Wu , Vince D. Calhoun , Dong Hye Ye

Knowledge graphs offer a structured representation of real-world entities and their relationships, enabling a wide range of applications from information retrieval to automated reasoning. In this paper, we conduct a systematic comparison…

机器学习 · 计算机科学 2025-07-31 Thanh Hoang-Minh

Depression is a widespread mental health issue, affecting an estimated 3.8% of the global population. It is also one of the main contributors to disability worldwide. Recently it is becoming popular for individuals to use social media…

计算与语言 · 计算机科学 2024-03-21 Ziyi Chen , Ren Yang , Sunyang Fu , Nansu Zong , Hongfang Liu , Ming Huang

Cardiovascular disease (CVD) remains the leading cause of mortality worldwide, underscoring the need for reliable and efficient predictive tools that support early intervention. Traditional diagnostic approaches rely on handcrafted features…

机器学习 · 计算机科学 2025-12-17 Tejaswani Dash , Gautam Datla , Anudeep Vurity , Tazeem Ahmad , Mohd Adnan , Saima Rafi , Saisha Patro , Saina Patro

Heterogeneous information network (HIN) embedding, aiming to map the structure and semantic information in a HIN to distributed representations, has drawn considerable research attention. Graph neural networks for HIN embeddings typically…

社会与信息网络 · 计算机科学 2020-07-07 Di Jin , Zhizhi Yu , Dongxiao He , Carl Yang , Philip S. Yu , Jiawei Han

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

机器学习 · 计算机科学 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

This study integrates causal inference, graph analysis, temporal complexity measures, and machine learning to examine whether individual symptom trajectories can reveal meaningful diagnostic patterns. Testing on a longitudinal dataset of…

应用统计 · 统计学 2025-07-22 Eleonora Vitanza , Pietro DeLellis , Chiara Mocenni , Manuel Ruiz Marin

We propose a novel deep neural network architecture to integrate imaging and genetics data, as guided by diagnosis, that provides interpretable biomarkers. Our model consists of an encoder, a decoder and a classifier. The encoder learns a…

Graph deep learning (GDL) has demonstrated impressive performance in predicting population-based brain disorders (BDs) through the integration of both imaging and non-imaging data. However, the effectiveness of GDL based methods heavily…

计算机视觉与模式识别 · 计算机科学 2025-03-31 Luhui Cai , Weiming Zeng , Hongyu Chen , Hua Zhang , Yueyang Li , Yu Feng , Hongjie Yan , Lingbin Bian , Wai Ting Siok , Nizhuan Wang

Emotional support conversation aims at reducing the emotional distress of the help-seeker, which is a new and challenging task. It requires the system to explore the cause of help-seeker's emotional distress and understand their…

计算与语言 · 计算机科学 2022-11-09 Wei Peng , Yue Hu , Luxi Xing , Yuqiang Xie , Yajing Sun , Yunpeng Li

Computer-aided early diagnosis of Alzheimer's disease (AD) and its prodromal form mild cognitive impairment (MCI) based on structure Magnetic Resonance Imaging (sMRI) has provided a cost-effective and objective way for early prevention and…

图像与视频处理 · 电气工程与系统科学 2021-11-16 Xin Zhang , Liangxiu Han , Wenyong Zhu , Liang Sun , Daoqiang Zhang

In this paper, we propose REASON, a novel framework that enables the automatic discovery of both intra-level (i.e., within-network) and inter-level (i.e., across-network) causal relationships for root cause localization. REASON consists of…

机器学习 · 计算机科学 2023-02-07 Dongjie Wang , Zhengzhang Chen , Jingchao Ni , Liang Tong , Zheng Wang , Yanjie Fu , Haifeng Chen

Brain networks has attracted the interests of many neuroscientists. From functional MRI (fMRI) data, statistical tools have been developed to recover brain networks. However, the dimensionality of whole-brain fMRI, usually in hundreds of…

统计方法学 · 统计学 2014-04-08 Xi Luo

Depression is a major global public health challenge and its early identification is crucial. Social media data provides a new perspective for depression detection, but existing methods face limitations such as insufficient accuracy,…

人工智能 · 计算机科学 2026-01-12 Yukun Yang

Major depressive disorder (MDD) is a heterogeneous condition; multiple underlying neurobiological substrates could be associated with treatment response variability. Understanding the sources of this variability and predicting outcomes has…

Prioritizing disease-associated genes is central to understanding the molecular mechanisms of complex disorders such as Alzheimer's disease (AD). Traditional network-based approaches rely on static centrality measures and often fail to…

机器学习 · 计算机科学 2026-03-04 Binon Teji , Subhajit Bandyopadhyay , Swarup Roy

Depression is a common mental disorder. Automatic depression detection tools using speech, enabled by machine learning, help early screening of depression. This paper addresses two limitations that may hinder the clinical implementations of…

计算与语言 · 计算机科学 2023-10-09 Qingkun Deng , Saturnino Luz , Sofia de la Fuente Garcia

The medical image is characterized by the inter-class indistinction, high variability, and noise, where the recognition of pixels is challenging. Unlike previous self-attention based methods that capture context information from one level,…

计算机视觉与模式识别 · 计算机科学 2019-11-26 Fei Ding , Gang Yang , Jinlu Liu , Jun Wu , Dayong Ding , Jie Xv , Gangwei Cheng , Xirong Li

Background: A therapeutic intervention in psychiatry can be viewed as an attempt to influence the brain's large-scale, dynamic network state transitions underlying cognition and behavior. Building on connectome-based graph analysis and…