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Recent advancements in single-cell genomics necessitate precision in gene panel selection to interpret complex biological data effectively. Those methods aim to streamline the analysis of scRNA-seq data by focusing on the most informative…

人工智能 · 计算机科学 2024-06-12 Weiliang Zhang , Zhen Meng , Dongjie Wang , Min Wu , Kunpeng Liu , Yuanchun Zhou , Meng Xiao

Although tremendous strides have been made in uncontrolled face detection, efficient face detection with a low computation cost as well as high precision remains an open challenge. In this paper, we point out that training data sampling and…

计算机视觉与模式识别 · 计算机科学 2021-05-12 Jia Guo , Jiankang Deng , Alexandros Lattas , Stefanos Zafeiriou

Differentiating signals from the background in micrographs is a critical initial step for cryogenic electron microscopy (cryo-EM), yet it remains laborious due to low signal-to-noise ratio (SNR), the presence of contaminants and densely…

图像与视频处理 · 电气工程与系统科学 2025-09-30 Szu-Chi Chung , Po-Cheng Chou

Advances in high-throughput sequencing technology have led to significant progress in measuring gene expressions at the single-cell level. The amount of publicly available single-cell RNA-seq (scRNA-seq) data is already surpassing 50M…

机器学习 · 计算机科学 2024-02-27 Jing Gong , Minsheng Hao , Xingyi Cheng , Xin Zeng , Chiming Liu , Jianzhu Ma , Xuegong Zhang , Taifeng Wang , Le Song

We introduce a machine learning-based method for fully automated diagnosis of sickle cell disease of poor-quality unstained images of a mobile microscope. Our method is capable of distinguishing between diseased, trait (carrier), and normal…

计算机视觉与模式识别 · 计算机科学 2021-03-31 Sahar A. Nasser , Debjani Paul , Suyash P. Awate

Foundation models for single-cell RNA sequencing (scRNA-seq) have shown promising capabilities in capturing gene expression patterns. However, current approaches face critical limitations: they ignore biological prior knowledge encoded in…

机器学习 · 计算机科学 2025-03-04 Mufan Qiu , Xinyu Hu , Fengwei Zhan , Sukwon Yun , Jie Peng , Ruichen Zhang , Bhavya Kailkhura , Jiekun Yang , Tianlong Chen

Single-cell RNA sequencing (scRNA-seq) has revolutionized biological discovery, providing an unbiased picture of cellular heterogeneity in tissues. While scRNA-seq has been used extensively to provide insight into both healthy systems and…

基因组学 · 定量生物学 2020-03-16 Neal G. Ravindra , Arijit Sehanobish , Jenna L. Pappalardo , David A. Hafler , David van Dijk

Random Forests (RF) are among the state-of-the-art in many machine learning applications. With the ongoing integration of ML models into everyday life, the deployment and continuous application of models becomes more and more an important…

机器学习 · 计算机科学 2021-10-20 Sebastian Buschjäger , Katharina Morik

This paper addresses the problem of depth estimation from a single still image. Inspired by recent works on multi- scale convolutional neural networks (CNN), we propose a deep model which fuses complementary information derived from…

计算机视觉与模式识别 · 计算机科学 2017-04-10 Dan Xu , Elisa Ricci , Wanli Ouyang , Xiaogang Wang , Nicu Sebe

Identification and quantification of condition-specific transcripts using RNA-Seq is vital in transcriptomics research. While initial efforts using mathematical or statistical modeling of read counts or per-base exonic signal have been…

定量方法 · 定量生物学 2013-02-26 Tin Chi Nguyen , Nan Deng , Dongxiao Zhu

Random forest (RF) stands out as a highly favored machine learning approach for classification problems. The effectiveness of RF hinges on two key factors: the accuracy of individual trees and the diversity among them. In this study, we…

机器学习 · 计算机科学 2024-10-28 Ye-eun Kim , Seoung Yun Kim , Hyunjoong Kim

In recommendation systems, the traditional multi-stage paradigm, which includes retrieval and ranking, often suffers from information loss between stages and diminishes performance. Recent advances in generative models, inspired by natural…

信息检索 · 计算机科学 2025-04-24 Luankang Zhang , Kenan Song , Yi Quan Lee , Wei Guo , Hao Wang , Yawen Li , Huifeng Guo , Yong Liu , Defu Lian , Enhong Chen

Across many areas, from neural tracking to database entity resolution, manual assessment of clusters by human experts presents a bottleneck in rapid development of scalable and specialized clustering methods. To solve this problem we…

机器学习 · 统计学 2020-03-20 Hanlin Zhu , Xue Li , Liuyang Sun , Fei He , Zhengtuo Zhao , Lan Luan , Ngoc Mai Tran , Chong Xie

Spiking Neural Networks (SNNs) have garnered substantial attention in brain-like computing for their biological fidelity and the capacity to execute energy-efficient spike-driven operations. As the demand for heightened performance in SNNs…

计算机视觉与模式识别 · 计算机科学 2024-07-09 Yimeng Shan , Xuerui Qiu , Rui-jie Zhu , Jason K. Eshraghian , Malu Zhang , Haicheng Qu

Single-cell RNA-seq provides detailed molecular snapshots of individual cells but is notoriously noisy. Variability stems from biological differences and technical factors, such as amplification bias and limited RNA capture efficiency,…

机器学习 · 计算机科学 2026-02-27 Victor Chardès

Spiking neural networks (SNNs) are bio-inspired neural networks with asynchronous discrete and sparse characteristics, which have increasingly manifested their superiority in low energy consumption. Recent research is devoted to utilizing…

神经与进化计算 · 计算机科学 2023-04-20 Lang Feng , Qianhui Liu , Huajin Tang , De Ma , Gang Pan

Single-cell RNA sequencing (scRNA-seq) data exhibit strong and reproducible statistical structure. This has motivated the development of large-scale foundation models, such as TranscriptFormer, that use transformer-based architectures to…

基因组学 · 定量生物学 2026-02-19 Huan Souza , Pankaj Mehta

Unsupervised cell type identification is crucial for uncovering and characterizing heterogeneous populations in single cell omics studies. Although a range of clustering methods have been developed, most focus exclusively on intrinsic…

人工智能 · 计算机科学 2025-12-12 Liang Peng , Haopeng Liu , Yixuan Ye , Cheng Liu , Wenjun Shen , Si Wu , Hau-San Wong

We propose a simple, data-efficient pipeline that augments an implicit reconstruction network based on neural SDF-based CAD parts with a part-segmentation head trained under PartField-generated supervision. Unlike methods tied to fixed…

图形学 · 计算机科学 2025-10-07 Shen Fan , Przemyslaw Musialski

Multi-modal image segmentation faces real-world deployment challenges from incomplete/corrupted modalities degrading performance. While existing methods address training-inference modality gaps via specialized per-combination models, they…

计算机视觉与模式识别 · 计算机科学 2025-09-22 Xiaoqi Zhao , Youwei Pang , Chenyang Yu , Lihe Zhang , Huchuan Lu , Shijian Lu , Georges El Fakhri , Xiaofeng Liu