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Survival analysis, as a challenging task, requires integrating Whole Slide Images (WSIs) and genomic data for comprehensive decision-making. There are two main challenges in this task: significant heterogeneity and complex inter- and…

图像与视频处理 · 电气工程与系统科学 2024-06-17 Conghao Xiong , Hao Chen , Hao Zheng , Dong Wei , Yefeng Zheng , Joseph J. Y. Sung , Irwin King

We introduce Matched Machine Learning, a framework that combines the flexibility of machine learning black boxes with the interpretability of matching, a longstanding tool in observational causal inference. Interpretability is paramount in…

统计方法学 · 统计学 2023-04-05 Marco Morucci , Cynthia Rudin , Alexander Volfovsky

Weighted model integration (WMI) extends weighted model counting (WMC) in providing a computational abstraction for probabilistic inference in mixed discrete-continuous domains. WMC has emerged as an assembly language for state-of-the-art…

人工智能 · 计算机科学 2020-01-14 Anton Fuxjaeger , Vaishak Belle

To tackle interpretability in deep learning, we present a novel framework to jointly learn a predictive model and its associated interpretation model. The interpreter provides both local and global interpretability about the predictive…

机器学习 · 计算机科学 2022-02-24 Jayneel Parekh , Pavlo Mozharovskyi , Florence d'Alché-Buc

Rapid progress in machine learning and deep learning has enabled a wide range of applications in the electricity load forecasting of power systems, for instance, univariate and multivariate short-term load forecasting. Though the strong…

机器学习 · 计算机科学 2024-02-20 Yuqi Jiang , Yan Li , Yize Chen

Sentence embeddings are central to modern NLP and AI systems, yet little is known about their internal structure. While we can compare these embeddings using measures such as cosine similarity, the contributing features are not…

计算与语言 · 计算机科学 2025-06-11 Matthieu Tehenan , Vikram Natarajan , Jonathan Michala , Milton Lin , Juri Opitz

Bayesian neural networks with latent variables are scalable and flexible probabilistic models: They account for uncertainty in the estimation of the network weights and, by making use of latent variables, can capture complex noise patterns…

A key barrier to interpreting large language models is polysemanticity, where neurons activate for multiple unrelated concepts. Sparse autoencoders (SAEs) have been proposed to mitigate this issue by transforming dense activations into…

机器学习 · 计算机科学 2025-10-20 Moghis Fereidouni , Muhammad Umair Haider , Peizhong Ju , A. B. Siddique

Deep learning has achieved remarkable success across many domains, but it has also created a growing demand for interpretability in model predictions. Although many explainable machine learning methods have been proposed, post-hoc…

机器学习 · 计算机科学 2026-01-28 Shijian Xu , Marcello Massimo Negri , Volker Roth

Brain decoding is a popular multivariate approach for hypothesis testing in neuroimaging. It is well known that the brain maps derived from weights of linear classifiers are hard to interpret because of high correlations between predictors,…

机器学习 · 统计学 2016-03-30 Seyed Mostafa Kia

It is well-known in the field of lossless data compression that probabilistic next-symbol prediction can be used to compress sequences of symbols. Deep neural networks are able to capture rich dependencies in data, offering a powerful means…

信息论 · 计算机科学 2026-03-10 Aviv Adler , Jennifer Tang

While deep learning offers powerful capabilities for scientific research, its application is often hindered by a lack of quantitative reliability. To address this, we introduce a probabilistic denoising framework that simultaneously…

强关联电子 · 物理学 2026-05-11 Younsik Kim , Changyoung Kim

Large Language Models (LLMs) have achieved unprecedented breakthroughs in various natural language processing domains. However, the enigmatic ``black-box'' nature of LLMs remains a significant challenge for interpretability, hampering…

计算与语言 · 计算机科学 2023-12-27 Zhen Tan , Tianlong Chen , Zhenyu Zhang , Huan Liu

Interpretation of deep learning remains a very challenging problem. Although the Class Activation Map (CAM) is widely used to interpret deep model predictions by highlighting object location, it fails to provide insight into the salient…

计算机视觉与模式识别 · 计算机科学 2024-05-30 Yuguang Yang , Runtang Guo , Sheng Wu , Yimi Wang , Juan Zhang , Xuan Gong , Baochang Zhang

Diffusion probabilistic models (DPMs) have achieved remarkable quality in image generation that rivals GANs'. But unlike GANs, DPMs use a set of latent variables that lack semantic meaning and cannot serve as a useful representation for…

计算机视觉与模式识别 · 计算机科学 2022-03-14 Konpat Preechakul , Nattanat Chatthee , Suttisak Wizadwongsa , Supasorn Suwajanakorn

Integrating heterogeneous biomedical data including imaging, omics, and clinical records supports accurate diagnosis and personalised care. Graph-based models fuse such non-Euclidean data by capturing spatial and relational structure, yet…

基因组学 · 定量生物学 2025-05-06 Alireza Sadeghi , Farshid Hajati , Ahmadreza Argha , Nigel H Lovell , Min Yang , Hamid Alinejad-Rokny

Precision cancer medicine aims to determine the optimal treatment for each patient. In-vitro cancer drug sensitivity screens combined with multi-omics characterization of the cancer cells have become an important tool to achieve this aim.…

统计方法学 · 统计学 2024-03-14 Zhi Zhao , Marco Banterle , Alex Lewin , Manuela Zucknick

The DEDICOM algorithm provides a uniquely interpretable matrix factorization method for symmetric and asymmetric square matrices. We employ a new row-stochastic variation of DEDICOM on the pointwise mutual information matrices of text…

计算与语言 · 计算机科学 2025-07-23 Lars Hillebrand , David Biesner , Christian Bauckhage , Rafet Sifa

Translating potential disease biomarkers between multi-species 'omics' experiments is a new direction in biomedical research. The existing methods are limited to simple experimental setups such as basic healthy-diseased comparisons. Most of…

机器学习 · 统计学 2010-12-16 Ilkka Huopaniemi , Tommi Suvitaival , Matej Orešič , Samuel Kaski

Recent work has demonstrated that complex visual stimuli can be decoded from human brain activity using deep generative models, offering new ways to probe how the brain represents real-world scenes. However, many existing approaches first…

计算机视觉与模式识别 · 计算机科学 2026-03-03 Pinyuan Feng , Hossein Adeli , Wenxuan Guo , Fan Cheng , Ethan Hwang , Nikolaus Kriegeskorte