相关论文: HiF-DTA: Hierarchical Feature Learning Network for…

Over the last two decades, topological data analysis (TDA) has emerged as a very powerful data analytic approach which can deal with various data modalities of varying complexities. One of the most commonly used tools in TDA is persistent…

Accurate prediction of drug-target interactions (DTI) is pivotal in drug discovery. However, existing approaches often fail to capture deep intra-modal feature interactions or achieve effective cross-modal alignment, limiting predictive…

Recently, deep neural network (DNN)-based drug-target interaction (DTI) models were highlighted for their high accuracy with affordable computational costs. Yet, the models' insufficient generalization remains a challenging problem in the…

High Content Imaging (HCI) plays a vital role in modern drug discovery and development pipelines, facilitating various stages from hit identification to candidate drug characterization. Applying machine learning models to these datasets can…

Multisource domain adaptation (MDA) aims to use multiple source datasets with available labels to infer labels on a target dataset without available labels for target supervision. Prior works on MDA in the literature is ad-hoc as the…

Infrared small object detection is an important computer vision task involving the recognition and localization of tiny objects in infrared images, which usually contain only a few pixels. However, it encounters difficulties due to the…

Hyperspectral anomaly detection (HAD) aims to identify rare and irregular targets in high-dimensional hyperspectral images (HSIs), which are often noisy and unlabelled data. Existing deep learning methods either fail to capture long-range…

Machine learning has emerged as a powerful tool for predicting molecular properties in chemical reaction networks with reduced computational cost. However, accurately predicting energies of transition state (TS) structures remains a…

Early and accurate diagnosis of Alzheimer's disease (AD) remains a critical challenge in neuroimaging-based clinical decision support systems. In this work, we propose a novel hybrid deep learning framework that integrates Topological Data…

Topological data analysis (TDA) is a relatively new field that is gaining rapid adoption due to its robustness and ability to effectively describe complex datasets by quantifying geometric information. In imaging contexts, TDA typically…

Accurate taxonomic identification of diatoms is essential for aquatic ecosystem monitoring, yet conventional methods depend heavily on expert taxonomists. Recent deep learning approaches improve automation, but most treat diatom recognition…

Discovering molecules with desirable molecular properties, including ADMET profiles, is of great importance in drug discovery. Existing approaches typically employ deep learning models, such as Graph Neural Networks (GNNs) and Transformers,…

The emerging research shows that lncRNAs are associated with a series of complex human diseases. However, most of the existing methods have limitations in identifying nonlinear lncRNA-disease associations (LDAs), and it remains a huge…

Latent Dirichlet Allocation (LDA) is a three-level hierarchical Bayesian model for topic inference. In spite of its great success, inferring the latent topic distribution with LDA is time-consuming. Motivated by the transfer learning…

The rapid development of deep learning provides a better solution for the end-to-end reconstruction of hyperspectral image (HSI). However, existing learning-based methods have two major defects. Firstly, networks with self-attention usually…

Dynamic Facial Expression Recognition (DFER) plays a critical role in affective computing and human-computer interaction. Although existing methods achieve comparable performance, they inevitably suffer from performance degradation under…

Unsupervised Domain Adaptation (UDA) is essential for enabling semantic segmentation in new domains without requiring costly pixel-wise annotations. State-of-the-art (SOTA) UDA methods primarily use self-training with architecturally…

Considerable research attention has been paid to table detection by developing not only rule-based approaches reliant on hand-crafted heuristics but also deep learning approaches. Although recent studies successfully perform table detection…

Prediction and discovery of new materials with desired properties are at the forefront of quantum science and technology research. A major bottleneck in this field is the computational resources and time complexity related to finding new…

Rich data and powerful machine learning models allow us to design drugs for a specific protein target \textit{in silico}. Recently, the inclusion of 3D structures during targeted drug design shows superior performance to other target-free…