相关论文: HiF-DTA: Hierarchical Feature Learning Network for…

Topological data analysis (TDA) provides insight into data shape. The summaries obtained by these methods are principled global descriptions of multi-dimensional data whilst exhibiting stable properties such as robustness to deformation and…

Hyperspectral image (HSI) and synthetic aperture radar (SAR) data joint classification is a crucial and yet challenging task in the field of remote sensing image interpretation. However, feature modeling in existing methods is deficient to…

Hierarchical latent tree analysis (HLTA) is recently proposed as a new method for topic detection. It differs fundamentally from the LDA-based methods in terms of topic definition, topic-document relationship, and learning method. It has…

Annotation scarcity and cross-modality/stain data distribution shifts are two major obstacles hindering the application of deep learning models for nuclei analysis, which holds a broad spectrum of potential applications in digital…

We introduce Deep Linear Discriminant Analysis (DeepLDA) which learns linearly separable latent representations in an end-to-end fashion. Classic LDA extracts features which preserve class separability and is used for dimensionality…

Predicting protein-ligand binding affinity remains intractable for multi-domain proteins, where inter-domain dynamics govern molecular recognition. Existing geometric deep learning methods typically treat proteins as monolithic static…

We introduce a new method of performing high dimensional discriminant analysis, which we call multiDA. We achieve this by constructing a hybrid model that seamlessly integrates a multiclass diagonal discriminant analysis model and feature…

Knowledge distillation has become increasingly important in model compression. It boosts the performance of a miniaturized student network with the supervision of the output distribution and feature maps from a sophisticated teacher…

Accurate prediction of protein-ligand binding affinities is an essential challenge in structure-based drug design. Despite recent advances in data-driven methods for affinity prediction, their accuracy is still limited, partially because…

Accurate prediction of drug-target interactions (DTI) is pivotal for drug discovery, yet existing methods often fail to address challenges like cross-domain generalization, cold-start prediction, and interpretability. In this work, we…

Drug-target interaction (DTI) prediction plays a crucial role in drug discovery, and deep learning approaches have achieved state-of-the-art performance in this field. We introduce an ensemble of deep learning models (EnsembleDLM) for DTI…

Convolutional Neural Network (CNN) struggle to capture the multi-dimensional structural information of complex high-dimensional data, which limits their feature learning capability. This paper proposes a feature fusion method based on…

Identifying novel drug-target interactions (DTI) is a critical and rate limiting step in drug discovery. While deep learning models have been proposed to accelerate the identification process, we show that state-of-the-art models fail to…

In medical images, various types of lesions often manifest significant differences in their shape and texture. Accurate medical image segmentation demands deep learning models with robust capabilities in multi-scale and boundary feature…

Establishing the correct correspondence of feature points is a fundamental task in computer vision. However, the presence of numerous outliers among the feature points can significantly affect the matching results, reducing the accuracy and…

Precision pathology relies on detecting fine-grained morphological abnormalities within specific Regions of Interest (ROIs), as these local, texture-rich cues - rather than global slide contexts - drive expert diagnostic reasoning. While…

Utilizing hyperspectral remote sensing technology enables the extraction of fine-grained land cover classes. Typically, satellite or airborne images used for training and testing are acquired from different regions or times, where the same…

Data augmentation is an effective technique to improve the generalization of deep neural networks. Recently, AutoAugment proposed a well-designed search space and a search algorithm that automatically finds augmentation policies in a…

Drug combination therapy is a well-established strategy for disease treatment with better effectiveness and less safety degradation. However, identifying novel drug combinations through wet-lab experiments is resource intensive due to the…

Source-free Unsupervised Domain Adaptation (SFDA) aims to classify target samples by only accessing a pre-trained source model and unlabelled target samples. Since no source data is available, transferring the knowledge from the source…