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A class of multivariate mixed survival models for continuous and discrete time with a complex covariance structure is introduced in a context of quantitative genetic applications. The methods introduced can be used in many applications in…

应用统计 · 统计学 2014-05-06 Rafael Pimentel Maia , Per Madsen , Rodrigo Labouriau

The computational cost associated with high-fidelity CFD simulations remains a significant bottleneck in the automotive design and optimization cycle. While ML-based surrogate models have emerged as a promising alternative to accelerate…

机器学习 · 计算机科学 2025-09-01 Mohammad Amin Nabian , Sanjay Choudhry

Healthcare systems generate diverse multimodal data, including Electronic Health Records (EHR), clinical notes, and medical images. Effectively leveraging this data for clinical prediction is challenging, particularly as real-world samples…

机器学习 · 计算机科学 2025-09-01 Xiaoyang Wang , Christopher C. Yang

Researchers are usually interested in examining the impact of covariates when separating heterogeneous samples into latent classes that are more homogeneous. The majority of theoretical and empirical studies with such aims have focused on…

统计方法学 · 统计学 2022-05-10 Jin Liu , Robert A. Perera

Scaling large language models has driven remarkable advancements across various domains, yet the continual increase in model size presents significant challenges for real-world deployment. The Mixture of Experts (MoE) architecture offers a…

机器学习 · 计算机科学 2025-03-18 Shwai He , Daize Dong , Liang Ding , Ang Li

The advancement of deep learning has led to the emergence of Mixture-of-Experts (MoEs) models, known for their dynamic allocation of computational resources based on input. Despite their promise, MoEs face challenges, particularly in terms…

计算与语言 · 计算机科学 2024-04-09 Alexandre Muzio , Alex Sun , Churan He

As in many fields of medical research, survival analysis has witnessed a growing interest in the application of deep learning techniques to model complex, high-dimensional, heterogeneous, incomplete, and censored medical data. Current…

机器学习 · 计算机科学 2023-12-25 Patricia A. Apellániz , Juan Parras , Santiago Zazo

In many clinical contexts, estimating effects of treatment in time-to-event data is complicated not only by confounding, censoring, and heterogeneity, but also by the presence of a cured subpopulation in which the event of interest never…

统计方法学 · 统计学 2026-02-06 Yuqi Li , Quinn Lanners , Matthew M. Engelhard

The Mixture-of-Experts (MoE) model has succeeded in deep learning (DL). However, its complex architecture and advantages over dense models in image classification remain unclear. In previous studies, MoE performance has often been affected…

机器学习 · 计算机科学 2025-03-13 Bakary Badjie , José Cecílio , António Casimiro

Machine learning applications for longitudinal electronic health records often forecast the risk of events at fixed time points, whereas survival analysis achieves dynamic risk prediction by estimating time-to-event distributions. Here, we…

机器学习 · 计算机科学 2024-11-26 Munib Mesinovic , Peter Watkinson , Tingting Zhu

Conventional survival analysis methods are typically ineffective to characterize heterogeneity in the population while such information can be used to assist predictive modeling. In this study, we propose a hybrid survival analysis method,…

机器学习 · 计算机科学 2024-04-09 Bojian Hou , Hongming Li , Zhicheng Jiao , Zhen Zhou , Hao Zheng , Yong Fan

Mixture of Experts (MoE) offers remarkable performance and computational efficiency by selectively activating subsets of model parameters. Traditionally, MoE models use homogeneous experts, each with identical capacity. However, varying…

We propose Preferential MoE, a novel human-ML mixture-of-experts model that augments human expertise in decision making with a data-based classifier only when necessary for predictive performance. Our model exhibits an interpretable gating…

机器学习 · 计算机科学 2021-01-15 Melanie F. Pradier , Javier Zazo , Sonali Parbhoo , Roy H. Perlis , Maurizio Zazzi , Finale Doshi-Velez

Mixture of Experts (MoE) is a popular framework for modeling heterogeneity in data for regression, classification, and clustering. For regression and cluster analyses of continuous data, MoE usually use normal experts following the Gaussian…

统计方法学 · 统计学 2017-01-26 Faicel Chamroukhi

Mixture-of-Experts (MoE) architectures achieve parameter efficiency through conditional computation, yet contemporary designs suffer from two fundamental limitations: structural parameter isolation that causes catastrophic forgetting, and…

机器学习 · 计算机科学 2026-01-21 Yuxing Gan , Ziyu Lei

Survival analysis is a challenging variation of regression modeling because of the presence of censoring, where the outcome measurement is only partially known, due to, for example, loss to follow up. Such problems come up frequently in…

机器学习 · 计算机科学 2022-06-28 Chirag Nagpal , Steve Yadlowsky , Negar Rostamzadeh , Katherine Heller

Mixture-of-Experts (MoE) models have shown remarkable capability in instruction tuning, especially when the number of tasks scales. However, previous methods simply merge all training tasks (e.g. creative writing, coding, and mathematics)…

计算与语言 · 计算机科学 2024-06-18 Tong Zhu , Daize Dong , Xiaoye Qu , Jiacheng Ruan , Wenliang Chen , Yu Cheng

Understanding consumer choice is fundamental to marketing and management research, as firms increasingly seek to personalize offerings and optimize customer engagement. Traditional choice modeling frameworks, such as multinomial logit (MNL)…

机器学习 · 计算机科学 2025-03-11 Diego Vallarino

Integrating the different data modalities of cancer patients can significantly improve the predictive performance of patient survival. However, most existing methods ignore the simultaneous utilization of rich semantic features at different…

计算机视觉与模式识别 · 计算机科学 2024-05-14 Liangrui Pan , Yijun Peng , Yan Li , Yiyi Liang , Liwen Xu , Qingchun Liang , Shaoliang Peng

Real-world time series exhibit complex and evolving dynamics, making accurate forecasting extremely challenging. Recent multi-modal forecasting methods leverage textual information such as news reports to improve prediction, but most rely…

机器学习 · 计算机科学 2026-01-30 Lige Zhang , Ali Maatouk , Jialin Chen , Leandros Tassiulas , Rex Ying