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Glioblastoma is profoundly heterogeneous in microstructure and vasculature, which may lead to tumor regional diversity and distinct treatment response. Although successful in tumor sub-region segmentation and survival prediction, radiomics…

图像与视频处理 · 电气工程与系统科学 2021-09-30 Yifan Li , Chao Li , Stephen Price , Carola-Bibiane Schönlieb , Xi Chen

Wide heterogeneity exists in cancer patients' survival, ranging from a few months to several decades. To accurately predict clinical outcomes, it is vital to build an accurate predictive model that relates patients' molecular profiles with…

机器学习 · 统计学 2023-10-12 Yaohua Rong , Sihai Dave Zhao , Xia Zheng , Yi Li

GBM (Glioblastoma multiforme) is the most aggressive type of brain tumor in adults that has a short survival rate even after aggressive treatment with surgery and radiation therapy. The changes on magnetic resonance imaging (MRI) for…

图像与视频处理 · 电气工程与系统科学 2023-06-07 M. S. Sadique , W. Farzana , A. Temtam , E. Lappinen , A. Vossough , K. M. Iftekharuddin

The research paper presents a novel approach to optimizing the tensile stress of Triply Periodic Minimal Surface (TPMS) structures through machine learning and Simulated Annealing (SA). The study evaluates the performance of Random Forest,…

材料科学 · 物理学 2024-06-11 Akshansh Mishra

Multi-state survival analysis (MSA) uses multi-state models for the analysis of time-to-event data. In medical applications, MSA can provide insights about the complex disease progression in patients. A key challenge in MSA is the accurate…

机器学习 · 计算机科学 2022-07-13 Md Mahmudur Rahman , Sanjay Purushotham

This research addresses the critical lack of comprehensive studies on feature scaling by systematically evaluating 12 scaling techniques - including several less common transformations - across 14 different Machine Learning algorithms and…

With an increasing focus on precision medicine in medical research, numerous studies have been conducted in recent years to clarify the relationship between treatment effects and patient characteristics. The treatment effects for patients…

统计方法学 · 统计学 2023-09-22 Ke Wan , Kensuke Tanioka , Toshio Shimokawa

We have applied a little-known data transformation to subsets of the Surveillance, Epidemiology, and End Results (SEER) publically available data of the National Cancer Institute (NCI) to make it suitable input to standard machine learning…

应用统计 · 统计学 2016-06-24 David Dooling , Angela Kim , Barbara McAneny , Jennifer Webster

As machine learning (ML)-based decision support tools proliferate in clinical practice, understanding how clinicians integrate personalized ML predictions alongside randomized controlled trial (RCT) evidence is critical. We designed a…

Prognostic information is essential for decision-making in breast cancer management. Recently trials have predominantly focused on genomic prognostication tools, even though clinicopathological prognostication is less costly and more widely…

The value of raw data is unlocked by converting it into information and knowledge that drives decision-making. Machine Learning (ML) algorithms are capable of analysing large datasets and making accurate predictions. Market segmentation,…

机器学习 · 统计学 2023-08-29 Diego Vallarino

Survival analysis plays a crucial role in understanding time-to-event (survival) outcomes such as disease progression. Despite recent advancements in causal mediation frameworks for survival analysis, existing methods are typically based on…

统计方法学 · 统计学 2026-05-07 Seungjun Ahn , Weijia Fu , Maaike van Gerwen , Lei Liu , Zhigang Li

Risk prediction models are widely used to guide real-world decision-making in areas such as healthcare and economics, and they also play a key role in estimating nuisance parameters in semiparametric inference. The super learner is a…

统计方法学 · 统计学 2025-09-05 Anders Munch , Thomas A. Gerds

Survival prediction models can potentially be used to guide treatment of glioblastoma patients. However, currently available MR imaging biomarkers holding prognostic information are often challenging to interpret, have difficulties…

图像与视频处理 · 电气工程与系统科学 2021-09-28 Sveinn Pálsson , Stefano Cerri , Hans Skovgaard Poulsen , Thomas Urup , Ian Law , Koen Van Leemput

In this work, we aim to predict the survival time (ST) of glioblastoma (GBM) patients undergoing different treatments based on preoperative magnetic resonance (MR) scans. The personalized and precise treatment planning can be achieved by…

计算机视觉与模式识别 · 计算机科学 2024-02-13 Xiaofeng Liu , Nadya Shusharina , Helen A Shih , C. -C. Jay Kuo , Georges El Fakhri , Jonghye Woo

Survival prediction of cancers is crucial for clinical practice, as it informs mortality risks and influences treatment plans. However, a static model trained on a single dataset fails to adapt to the dynamically evolving clinical…

机器学习 · 计算机科学 2026-01-21 Dianzhi Yu , Conghao Xiong , Yankai Chen , Wenqian Cui , Xinni Zhang , Yifei Zhang , Hao Chen , Joseph J. Y. Sung , Irwin King

In this paper, we describe a dataset relating to cellular and physical conditions of patients who are operated upon to remove colorectal tumours. This data provides a unique insight into immunological status at the point of tumour removal,…

机器学习 · 计算机科学 2016-11-15 Chris Roadknight , Uwe Aickelin , John Scholefield , Lindy Durrant

The paper proposes a novel approach of survival transformers and extreme gradient boosting models in predicting cognitive deterioration in individuals with mild cognitive impairment (MCI) using metabolomics data in the ADNI cohort. By…

机器学习 · 计算机科学 2024-09-25 Henry Musto , Daniel Stamate , Doina Logofatu , Daniel Stahl

Cardiovascular disease remains a leading cause of mortality in the contemporary world. Its association with smoking, elevated blood pressure, and cholesterol levels underscores the significance of these risk factors. This study addresses…

机器学习 · 计算机科学 2023-11-02 Jonayet Miah , Duc M Ca , Md Abu Sayed , Ehsanur Rashid Lipu , Fuad Mahmud , S M Yasir Arafat

As machine learning has become increasingly popular over the last few decades, so too has the number of machine learning interfaces for implementing these models. Whilst many R libraries exist for machine learning, very few offer extended…

统计计算 · 统计学 2021-03-19 Raphael Sonabend , Franz J. Király , Andreas Bender , Bernd Bischl , Michel Lang