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Purpose: To evaluate a proposed method to reconstruct CT numbers that accurately mimic conventional CT numbers from spectral CT data, as would have been produced by a conventional system without effects of beam hardening. Approach: We…

医学物理 · 物理学 2022-08-10 Fredrik Grönberg , Hans Bornefalk

Many clinical applications depend critically on the accurate differentiation and classification of different types of materials in patient anatomy. This work introduces a unified framework for accurate nonlinear material decomposition and…

医学物理 · 物理学 2018-03-19 Wei Zhao , Don Vernekohl , Fei Han , Bin Han , Hao Peng , Lei Xing , James K Min

Relative location prediction in computed tomography (CT) scan images is a challenging problem. In this paper, a regression model based on one-dimensional convolutional neural networks is proposed to determine the relative location of a CT…

计算机视觉与模式识别 · 计算机科学 2017-11-22 Jiajia Guo , Hongwei Du , Bensheng Qiu , Xiao Liang

Proton computed tomography (pCT) is a novel medical imaging modality for mapping the distribution of proton relative stopping power (RSP) in medical objects of interest. Compared to conventional X-ray computed tomography, where range…

Purpose: Following the clinical success of 177Lu-based therapies, accurate quantification of 177Lu using radionuclide calibrators (RNCs) and SPECT/CT is gaining importance as prerequisite for accurate treatment delivery and dosimetry.…

The production cross section of a top quark pair in association with a photon is measured in proton-proton collisions at a center-of-mass energy of 13 TeV. The data set, corresponding to an integrated luminosity of 137 fb$^{-1}$, was…

高能物理 - 实验 · 物理学 2021-12-30 CMS Collaboration

Clinical SPECT-MPI images of 345 patients acquired from a dedicated cardiac SPECT in list-mode format were retrospectively employed to predict normal-dose images from low-dose data at the half, quarter, and one-eighth-dose levels. A…

Radiotherapy is one of the main methods in the successful treatment of cancer. The tumor is irradiated with photons or charged particles (e.g. protons), and in the case of massive charged particles, the treatment results in less unnecessary…

医学物理 · 物理学 2019-03-20 Monika Varga-Kofarago

Upright position CT scans make it possible for full-length-body imaging at conditions more relevant to daily situations, but the substantial weight of the upright CT scanners increases the risks to floor's stability and patients'safety.…

医学物理 · 物理学 2023-11-13 Tong Lin , Tianling Lyu , Zhan Wu , Yan Xi , Wentao Zhu , Yang Chen

A new set of fluence-to-dose conversion coefficients based on the Chinese reference adult voxel phantoms CRAM and CRAF are presented for six idealized external neutron exposures from 10-8 MeV to 20 MeV. The voxel phantoms CRAM and CRAF were…

医学物理 · 物理学 2015-12-03 Huan Liu , Jun-Li Li , Rui Qiu , Yue Yang , Yu-Xi Pan , Li-Ye Liu

Cone-beam computed tomography (CBCT) is widely used for image-guided radiotherapy (IGRT). It provides real time visualization at low cost and dose. However, photon scattering and beam hindrance cause artifacts in CBCT. These include…

医学物理 · 物理学 2025-09-29 Alzahra Altalib , Chunhui Li , Alessandro Perelli

Proton therapy is a cancer treatment technique currently in growth worldwide. It offers advantages with respect to conventional X-ray and $\gamma$-ray radiotherapy, in particular, a better control of the dose deposition allowing to reach a…

PURPOSE: To develop an automated algorithm allowing extraction of quantitative corneal transparency parameters from clinical spectral-domain OCT images. To establish a representative dataset of normative transparency values from healthy…

Quantitative estimation of contrast agent concentration is made possible by spectral CT and material decomposition. There are several approaches to modulate the sensitivity of the imaging system to obtain the different spectral channels…

医学物理 · 物理学 2020-10-16 Matthew Tivnan , Wenying Wang , Grace Gang , Eleni Liapi , Peter Noel , J. Webster Stayman

Purpose: In some proton therapy facilities, patient alignment relies on two 2D orthogonal kV images, taken at fixed, oblique angles, as no 3D on-the-bed imaging is available. The visibility of the tumor in kV images is limited since the…

计算机视觉与模式识别 · 计算机科学 2023-10-19 Yuzhen Ding , Hongying Feng , Yunze Yang , Jason Holmes , Zhengliang Liu , David Liu , William W. Wong , Nathan Y. Yu , Terence T. Sio , Steven E. Schild , Baoxin Li , Wei Liu

Ultra sparse-view computed tomography (CT) algorithms can reduce radiation exposure of patients, but those algorithms lack an explicit cycle consistency loss minimization and an explicit log-likelihood maximization in testing. Here, we…

图像与视频处理 · 电气工程与系统科学 2021-10-04 Hisaichi Shibata , Shouhei Hanaoka , Yukihiro Nomura , Takahiro Nakao , Tomomi Takenaga , Naoto Hayashi , Osamu Abe

CBCT images suffer from acute shading artifacts primarily due to scatter. Numerous image-domain correction algorithms have been proposed in the literature that use patient-specific planning CT images to estimate shading contributions in…

计算机视觉与模式识别 · 计算机科学 2018-01-18 Awais Ashfaq , Jonas Adler

Introduction: Terbium-149 ($^{149}$Tb) is a promising radionuclide for targeted $\alpha$ therapy that has a non-zero branching ratio (BR) for positron decay. However, its relatively low positron branching fraction and multiple prompt…

Objective: To develop and validate an independent Monet Carlo dose calculation engine to support for software verification of treatment planning systems and quality assurance workflow. Method: GATE Monte Carlo toolkit was employed to…

医学物理 · 物理学 2021-07-27 A. Asadi , A. Akhavanallaf , S. A. Hosseini , N. vosoughi , H. Zaidi

FLASH-RT has proven beneficial in preclinical studies. However, the lack of accurate real time 2D dosimetry is a limiting factor. In this work, an innovative solution for 2D real time dosimetry in UHDR electron beams is presented. The…