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相关论文: Foundation Models in Dermatopathology: Skin Tissue…

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Tissue detection is a crucial first step in most digital pathology applications. Details of the segmentation algorithm are rarely reported, and there is a lack of studies investigating the downstream effects of a poor segmentation…

Skin diseases are among the most prevalent health concerns worldwide, yet conventional diagnostic methods are often costly, complex, and unavailable in low-resource settings. Automated classification using deep learning has emerged as a…

计算机视觉与模式识别 · 计算机科学 2025-09-08 Asif Newaz , Masum Mushfiq Ishti , A Z M Ashraful Azam , Asif Ur Rahman Adib

Pathologists are facing an increasing workload due to a growing volume of cases and the need for more comprehensive diagnoses. Aiming to facilitate workload reduction and faster turnaround times, we developed an artificial intelligence (AI)…

计算机视觉与模式识别 · 计算机科学 2024-10-15 Ruben T. Lucassen , Nikolas Stathonikos , Gerben E. Breimer , Mitko Veta , Willeke A. M. Blokx

In recent years, foundation models such as CLIP, DINO,and CONCH have demonstrated remarkable domain generalization and unsupervised feature extraction capabilities across diverse imaging tasks. However, systematic and independent…

计算机视觉与模式识别 · 计算机科学 2026-02-24 Lavish Ramchandani , Aashay Tinaikar , Dev Kumar Das , Rohit Garg , Tijo Thomas

Tissue segmentation is a routine preprocessing step to reduce the computational cost of whole slide image (WSI) analysis by excluding background regions. Traditional image processing techniques are commonly used for tissue segmentation, but…

图像与视频处理 · 电气工程与系统科学 2024-01-25 Ruben T. Lucassen , Willeke A. M. Blokx , Mitko Veta

Whole slide images (WSIs) are the gold standard for pathological diagnosis and sub-typing. Current main-stream two-step frameworks employ offline feature encoders trained without domain-specific knowledge. Among them, attention-based…

计算机视觉与模式识别 · 计算机科学 2026-02-17 Mingrui Ma , Chentao Li , Pan Huang , Jing Qin

The process of digitising histology slides involves multiple factors that can affect a whole slide image's (WSI) final appearance, including the staining protocol, scanner, and tissue type. This variability constitutes a domain shift and…

计算机视觉与模式识别 · 计算机科学 2024-11-26 Manahil Raza , Saad Bashir , Talha Qaiser , Nasir Rajpoot

Representation learning of pathology whole-slide images (WSIs) has primarily relied on weak supervision with Multiple Instance Learning (MIL). This approach leads to slide representations highly tailored to a specific clinical task.…

计算机视觉与模式识别 · 计算机科学 2025-03-25 Tim Lenz , Peter Neidlinger , Marta Ligero , Georg Wölflein , Marko van Treeck , Jakob Nikolas Kather

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

定量方法 · 定量生物学 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

The field of computational pathology has recently seen rapid advances driven by the development of modern vision foundation models (FMs), typically trained on vast collections of pathology images. Recent studies demonstrate that increasing…

计算机视觉与模式识别 · 计算机科学 2025-04-08 Mikhail Karasikov , Joost van Doorn , Nicolas Känzig , Melis Erdal Cesur , Hugo Mark Horlings , Robert Berke , Fei Tang , Sebastian Otálora

Recent rapid progress in the field of computational pathology has been enabled by foundation models. These models are beginning to move beyond encoding image patches towards whole-slide understanding but their clinical utility remains…

Deep Learning approaches in dermatological image classification have shown promising results, yet the field faces significant methodological challenges that impede proper evaluation. This paper presents a dual contribution: first, a…

图像与视频处理 · 电气工程与系统科学 2025-02-05 Łukasz Miętkiewicz , Leon Ciechanowski , Dariusz Jemielniak

Cancer survival prediction from whole slide images (WSIs) is a challenging task in computational pathology due to the large size, irregular shape, and high granularity of the WSIs. These characteristics make it difficult to capture the full…

图像与视频处理 · 电气工程与系统科学 2025-03-05 Rustin Soraki , Huayu Wang , Joann G. Elmore , Linda Shapiro

Artificial intelligence foundation models are increasingly deployed for prostate cancer Gleason grading, where GP3/GP4 distinction directly impacts treatment decisions. However, these models may achieve high validation accuracy by learning…

计算机视觉与模式识别 · 计算机科学 2025-12-18 Joshua L. Ebbert , Dennis Della Corte

Whole Slide Image (WSI) classification poses unique challenges due to the vast image size and numerous non-informative regions, which introduce noise and cause data imbalance during feature aggregation. To address these issues, we propose…

计算机视觉与模式识别 · 计算机科学 2025-03-18 Jianwei Zhao , Xin Li , Fan Yang , Qiang Zhai , Ao Luo , Yang Zhao , Hong Cheng , Huazhu Fu

Automatic integration of whole slide images (WSIs) and gene expression profiles has demonstrated substantial potential in precision clinical diagnosis and cancer progression studies. However, most existing studies focus on individual gene…

计算机视觉与模式识别 · 计算机科学 2026-01-14 Junzhuo Liu , Xuemei Du , Daniel Reisenbuchler , Ye Chen , Markus Eckstein , Christian Matek , Friedrich Feuerhake , Dorit Merhof

Convolutional Neural Networks (CNN) are state-of-the-art models for many image classification tasks. However, to recognize cancer subtypes automatically, training a CNN on gigapixel resolution Whole Slide Tissue Images (WSI) is currently…

计算机视觉与模式识别 · 计算机科学 2016-03-10 Le Hou , Dimitris Samaras , Tahsin M. Kurc , Yi Gao , James E. Davis , Joel H. Saltz

Foundation models are reshaping computational pathology by enabling transfer learning, where models pre-trained on vast datasets can be adapted for downstream diagnostic, prognostic, and therapeutic response tasks. Despite these advances,…

Deep neural networks are increasingly applied in automated histopathology. Yet, whole-slide images (WSIs) are often acquired at gigapixel sizes, rendering them computationally infeasible to analyze entirely at high resolution. Diagnostic…

图像与视频处理 · 电气工程与系统科学 2026-02-10 Tarun G , Naman Malpani , Gugan Thoppe , Sridharan Devarajan

Artificial intelligence (AI) has transformed digital pathology by enabling biomarker prediction from high-resolution whole-slide images (WSIs). However, current methods are computationally inefficient, processing thousands of redundant…